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4V3E
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BU of 4v3e by Molmil
The CIDRa domain from IT4var07 PfEMP1 bound to endothelial protein C receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOTHELIAL PROTEIN C RECEPTOR, ...
Authors:Lau, C.K.Y, Turner, L, Jespersen, J.S, Lowe, E.D, Petersen, B, Wang, C.W, Petersen, J.E.V, Lusingu, J, Theander, T.G, Lavstsen, T, Higgins, M.K.
Deposit date:2014-10-17
Release date:2014-12-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Conservation Despite Huge Sequence Diversity Allows Epcr Binding by the Pfemp1 Family Implicated in Severe Childhood Malaria.
Cell Host Microbe., 17, 2015
4V3D
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BU of 4v3d by Molmil
The CIDRa domain from HB3var03 PfEMP1 bound to endothelial protein C receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOTHELIAL PROTEIN C RECEPTOR, ...
Authors:Lau, C.K.Y, Turner, L, Jespersen, J.S, Lowe, E.D, Petersen, B, Wang, C.W, Petersen, J.E.V, Lusingu, J, Theander, T.G, Lavstsen, T, Higgins, M.K.
Deposit date:2014-10-17
Release date:2014-12-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Conservation Despite Huge Sequence Diversity Allows Epcr Binding by the Pfemp1 Family Implicated in Severe Childhood Malaria.
Cell Host Microbe., 17, 2015
8P2E
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BU of 8p2e by Molmil
Homotypic interacting B1 fab bound to Chondroitin Sulfate A
Descriptor: B1 fab heavy, B1 fab light
Authors:Raghavan, S.S.R, Dagil, R, Wang, K.T, Salanti, A.
Deposit date:2023-05-16
Release date:2024-06-05
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate.
Nat Commun, 15, 2024
7B52
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BU of 7b52 by Molmil
VAR2CSA full ectodomain
Descriptor: Erythrocyte membrane protein 1
Authors:Wang, K.T, Gourdon, P.E, Dagil, R, Salanti, A.
Deposit date:2020-12-03
Release date:2021-04-21
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding.
Nat Commun, 12, 2021
7B54
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BU of 7b54 by Molmil
VAR2CSA full ectodomain in present of plCS, DBL1-DBL4
Descriptor: VAR2CSA in presence of plCS, DBl1-DBL4,Erythrocyte membrane protein 1
Authors:Wang, K.T, Dagil, R, Gourdon, P.E, Salanti, A.
Deposit date:2020-12-03
Release date:2021-06-02
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding.
Nat Commun, 12, 2021
7NNH
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BU of 7nnh by Molmil
Cryo-EM structure of VAR2CSA FCR3 domain DBL5/6
Descriptor: Erythrocyte membrane protein 1
Authors:Wang, K.T, Dagil, R, Salanti, A, Gourdon, P.E.
Deposit date:2021-02-24
Release date:2021-06-02
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding.
Nat Commun, 12, 2021
8C3Y
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BU of 8c3y by Molmil
HB3VAR03 apo headstructure (PfEMP1 A)
Descriptor: PfEMP1
Authors:Raghavan, S.S.R, Lavstsen, T, Wang, K.T.
Deposit date:2022-12-29
Release date:2023-08-02
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1.
Structure, 31, 2023
8C44
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BU of 8c44 by Molmil
HB3VAR03 apo headstructure (PfEMP1 A) complexed with EPCR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, PHOSPHATIDYLETHANOLAMINE, ...
Authors:Raghavan, S.S.R, Lavstsen, T, Wang, K.T.
Deposit date:2022-12-31
Release date:2023-08-16
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1.
Structure, 31, 2023
5MZA
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BU of 5mza by Molmil
The DBLb domain of PF11_0521 PfEMP1 bound to human ICAM-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Erythrocyte membrane protein 1 (PfEMP1), ...
Authors:Lennartz, F, Higgins, M.K.
Deposit date:2017-01-31
Release date:2017-03-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.
Cell Host Microbe, 21, 2017

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數據於2024-10-30公開中

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