4J8R
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![BU of 4j8r by Molmil](/molmil-images/mine/4j8r) | Structure of an octapeptide repeat of the prion protein bound to the POM2 Fab antibody fragment | Descriptor: | Heavy chain of POM2 Fab, Light chain of POM2 Fab, Major prion protein | Authors: | Swayampakula, M, Baral, P.K, Kav, N.N.V, Aguzzi, A, James, M.N.G. | Deposit date: | 2013-02-14 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody. Protein Sci., 22, 2013
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4DGI
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![BU of 4dgi by Molmil](/molmil-images/mine/4dgi) | Structure of POM1 FAB fragment complexed with human PrPc Fragment 120-230 | Descriptor: | Major prion protein, POM1 Fab Heavy chain, POM1 Fab Light chain, ... | Authors: | Baral, P.K, Wieland, B, Swayampakula, M, James, M.N. | Deposit date: | 2012-01-26 | Release date: | 2012-10-31 | Last modified: | 2013-01-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1. Acta Crystallogr.,Sect.D, 68, 2012
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6AQ7
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![BU of 6aq7 by Molmil](/molmil-images/mine/6aq7) | Structure of POM6 FAB fragment complexed with mouse PrPc | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Major prion protein, ... | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2017-08-18 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion. FEBS J., 285, 2018
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4MA8
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![BU of 4ma8 by Molmil](/molmil-images/mine/4ma8) | Crystal structure of mouse prion protein complexed with Chlorpromazine | Descriptor: | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, Major prion protein, POM1 heavy chain, ... | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2013-08-15 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of prion inhibition by phenothiazine compounds. Structure, 22, 2014
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4MA7
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![BU of 4ma7 by Molmil](/molmil-images/mine/4ma7) | Crystal structure of mouse prion protein complexed with Promazine | Descriptor: | Major prion protein, POM1 heavy chain, POM1 light chain, ... | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2013-08-15 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural basis of prion inhibition by phenothiazine compounds. Structure, 22, 2014
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4H88
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![BU of 4h88 by Molmil](/molmil-images/mine/4h88) | Structure of POM1 FAB fragment complexed with mouse PrPc Fragment 120-230 | Descriptor: | Major prion protein, POM1 FAB CHAIN H, POM1 FAB CHAIN L, ... | Authors: | Baral, P.K, Wieland, B, Swayampakula, M, James, M.N. | Deposit date: | 2012-09-21 | Release date: | 2013-07-31 | Last modified: | 2013-09-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature, 501, 2013
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4YXL
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![BU of 4yxl by Molmil](/molmil-images/mine/4yxl) | Crystal structure of Syrian hamster prion protein complexed with POM1 FAB | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2015-03-23 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. J.Struct.Biol., 192, 2015
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4YXH
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![BU of 4yxh by Molmil](/molmil-images/mine/4yxh) | Crystal structure of Deer prion protein complexed with POM1 FAB | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2015-03-23 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. J.Struct.Biol., 192, 2015
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4YXK
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![BU of 4yxk by Molmil](/molmil-images/mine/4yxk) | Crystal structure of Elk prion protein complexed with POM1 FAB | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2015-03-23 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. J.Struct.Biol., 192, 2015
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4YX2
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![BU of 4yx2 by Molmil](/molmil-images/mine/4yx2) | Crystal structure of Bovine prion protein complexed with POM1 FAB | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2015-03-22 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. J.Struct.Biol., 192, 2015
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