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2KFX
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BU of 2kfx by Molmil
Structure of the N-terminal domain of human cardiac troponin C bound to calcium ion and to the inhibitor W7
Descriptor: CALCIUM ION, N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE, Troponin C, ...
Authors:Hoffman, R.M.B, Sykes, B.D.
Deposit date:2009-02-28
Release date:2009-06-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the inhibitor W7 bound to the regulatory domain of cardiac troponin C.
Biochemistry, 48, 2009
5CJQ
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BU of 5cjq by Molmil
Crystal structure of a trimeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
Descriptor: CR9114 heavy chain, CR9114 light chain, Designed influenza hemagglutinin stem #4900, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-07-14
Release date:2015-09-09
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015
5CJS
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BU of 5cjs by Molmil
Crystal structure of a monomeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 heavy chain, CR9114 light chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-07-15
Release date:2015-09-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015
4M5Z
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BU of 4m5z by Molmil
Crystal structure of broadly neutralizing antibody 5J8 bound to 2009 pandemic influenza hemagglutinin, HA1 subunit
Descriptor: Fab 5J8 heavy chain, Fab 5J8 light chain, Hemagglutinin HA1 chain
Authors:Hong, M, Lee, P.S, Wilson, I.A.
Deposit date:2013-08-08
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site.
J.Virol., 87, 2013
4M5Y
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BU of 4m5y by Molmil
Crystal structure of broadly neutralizing Fab 5J8
Descriptor: DI(HYDROXYETHYL)ETHER, Fab 5J8 heavy chain, Fab 5J8 light chain, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-08-08
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site.
J.Virol., 87, 2013
4M4Y
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BU of 4m4y by Molmil
Crystal structure of a 2009 H1N1 influenza virus hemagglutinin with a stabilization mutation HA2 E47G
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-08-07
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site.
J.Virol., 87, 2013
4NM8
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BU of 4nm8 by Molmil
Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8043, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-11-14
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.0041 Å)
Cite:A common solution to group 2 influenza virus neutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NM4
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BU of 4nm4 by Molmil
Crystal structure of broadly neutralizing antibody CR8043
Descriptor: Antibody CR8043, Heavy Chain, Light Chain, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-11-14
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A common solution to group 2 influenza virus neutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
2O7C
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BU of 2o7c by Molmil
Crystal structure of L-methionine-lyase from Pseudomonas
Descriptor: Methionine gamma-lyase, SULFATE ION
Authors:Misaki, S, Takimoto, A, Takakura, T, Yoshioka, T, Yamashita, M, Tamura, T, Tanaka, H, Inagaki, K.
Deposit date:2006-12-10
Release date:2007-12-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the antitumour enzyme L-methionine gamma-lyase from Pseudomonas putida at 1.8 A resolution
J.Biochem.(Tokyo), 141, 2007
1PG8
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BU of 1pg8 by Molmil
Crystal Structure of L-methionine alpha-, gamma-lyase
Descriptor: DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Allen, T.W, Sridhar, V, Prasad, G.S, Han, Q, Xu, M, Tan, Y, Hoffman, R.M, Ramaswamy, S.
Deposit date:2003-05-28
Release date:2004-06-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:
To Be Published
1PFF
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BU of 1pff by Molmil
Crystal Structure of Homocysteine alpha-, gamma-lyase at 1.8 Angstroms
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, methionine gamma-lyase
Authors:Allen, T.W, Sridhar, V, Prasad, S.G, Han, Q, Xu, M, Tan, Y, Hoffman, R.M, Ramaswamy, S.
Deposit date:2003-05-26
Release date:2004-08-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:

6CNW
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BU of 6cnw by Molmil
STRUCTURE OF HUMANIZED SINGLE DOMAIN ANTIBODY SD84
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, humanized antibody SD84h
Authors:Luo, J, Obmolova, O.
Deposit date:2018-03-09
Release date:2018-11-14
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYT
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BU of 6fyt by Molmil
Structure of H1 (A/solomon Islands/3/06) Influenza Hemagglutinin in complex with SD38
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Laursen, N.S, Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYS
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BU of 6fys by Molmil
Structure of single domain antibody SD83
Descriptor: 1,2-ETHANEDIOL, Single domain antibody SD83
Authors:Laursen, N.S, Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2022-03-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYW
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BU of 6fyw by Molmil
Structure of B/Brisbane/60/2008 Influenza Hemagglutinin in complex with SD83
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Laursen, N.S, Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYU
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BU of 6fyu by Molmil
Structure of H7(A/Shanghai/2/2013) Influenza Hemagglutinin in complex SD36
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Laursen, N.S, Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.643 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6CNV
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BU of 6cnv by Molmil
INFLUENZA B/BRISBANE HEMAGGLUTININ FAB CR9115 SD84H COMPLEX
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 Fab heavy chain, ...
Authors:Luo, J, Obmolova, G.
Deposit date:2018-03-09
Release date:2018-11-14
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6CK8
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BU of 6ck8 by Molmil
Crystal structure of anti-influenza single-domain llama antibody SD38
Descriptor: GLYCEROL, Llama antibody SD38, PENTAETHYLENE GLYCOL, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2018-02-27
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6OAC
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BU of 6oac by Molmil
PQR530 [(S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine] bound to the PI3Ka catalytic subunit p110alpha
Descriptor: 4-(difluoromethyl)-5-{4-[(3S)-3-methylmorpholin-4-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}pyridin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Authors:Burke, J.E, McPhail, J.A.
Deposit date:2019-03-15
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:(S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase.
J.Med.Chem., 62, 2019
6DJL
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BU of 6djl by Molmil
Crystal structure of the Rab11 GEF SH3BP5 bound to nucleotide free Rab11A
Descriptor: Ras-related protein Rab-11A, SH3 domain-binding protein 5
Authors:Burke, J.E, Jenkins, M.L, Boulanger, M.J.
Deposit date:2018-05-25
Release date:2018-09-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.10001159 Å)
Cite:Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5.
Nat Commun, 9, 2018
6TZZ
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BU of 6tzz by Molmil
Crystal Structure of Tetrahymena Thermophila Lipin Phosphatidic Acid Phosphatase with Magnesium
Descriptor: MAGNESIUM ION, Nuclear elongation and deformation protein
Authors:Khayyo, V.I, Airola, M.V.
Deposit date:2019-08-13
Release date:2020-03-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a lipin/Pah phosphatidic acid phosphatase
Nat Commun, 11, 2020
6TZY
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BU of 6tzy by Molmil
Crystal Structure of a lipin/Pah Phosphatidic Acid Phosphatase
Descriptor: CALCIUM ION, Nuclear elongation and deformation protein
Authors:Khayyo, V.I, Airola, M.V.
Deposit date:2019-08-13
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of a lipin/Pah Phosphatidic Acid Phosphatase
Nat Commun, 11, 2020
7LPQ
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BU of 7lpq by Molmil
Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with hit 9
Descriptor: Cytoplasmic protein, GLYCEROL, MAGNESIUM ION, ...
Authors:Pereira de Sa, N, Del Poeta, M, Airola, M.V.
Deposit date:2021-02-12
Release date:2021-09-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.
Nat Commun, 12, 2021
7LPO
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BU of 7lpo by Molmil
Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with tris
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytoplasmic protein, MAGNESIUM ION
Authors:Pereira de Sa, N, Del Poeta, M, Airola, M.V.
Deposit date:2021-02-12
Release date:2021-09-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.
Nat Commun, 12, 2021
7LPP
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BU of 7lpp by Molmil
Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with hit 1
Descriptor: 4-(hydroxymethyl)-1-[[2-(3-methoxyphenyl)-1,3-thiazol-5-yl]methyl]piperidin-4-ol, Cytoplasmic protein, GLYCEROL, ...
Authors:Pereira de Sa, N, Del Poeta, M, Airola, M.V.
Deposit date:2021-02-12
Release date:2021-09-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.
Nat Commun, 12, 2021

 

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數據於2024-07-24公開中

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