6DJL

Crystal structure of the Rab11 GEF SH3BP5 bound to nucleotide free Rab11A

Summary for 6DJL

Entry DOI	10.2210/pdb6djl/pdb
Descriptor	Ras-related protein Rab-11A, SH3 domain-binding protein 5 (2 entities in total)
Functional Keywords	rab gtpase, guanine nucleotide exchange factor, membrane trafficking, protein transport, signaling protein-protein transport complex, signaling protein/protein transport
Biological source	Homo sapiens (Human) More
Total number of polymer chains	8
Total formula weight	222895.27
Authors	Burke, J.E.,Jenkins, M.L.,Boulanger, M.J. (deposition date: 2018-05-25, release date: 2018-09-26, Last modification date: 2024-03-13)
Primary citation	Jenkins, M.L.,Margaria, J.P.,Stariha, J.T.B.,Hoffmann, R.M.,McPhail, J.A.,Hamelin, D.J.,Boulanger, M.J.,Hirsch, E.,Burke, J.E. Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5. Nat Commun, 9:3772-3772, 2018 Cited by PubMed: 30217979 DOI: 10.1038/s41467-018-06196-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.10001148084 Å)

Structure validation