7N8P
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![BU of 7n8p by Molmil](/molmil-images/mine/7n8p) | CLC-ec1 at pH 4.5 100mM Cl Swap | Descriptor: | H(+)/Cl(-) exchange transporter ClcA | Authors: | Fortea, E, Boudker, O, Accardi, A. | Deposit date: | 2021-06-15 | Release date: | 2022-11-16 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Structural basis of common gate activation in CLC transporters To Be Published
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7N9W
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![BU of 7n9w by Molmil](/molmil-images/mine/7n9w) | CLC-ec1 pH 4.5 100mM Cl Twist1 | Descriptor: | H(+)/Cl(-) exchange transporter ClcA | Authors: | Fortea, E, Boudker, O, Accardi, A. | Deposit date: | 2021-06-18 | Release date: | 2022-11-16 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Structural basis of common gate activation in CLC transporters To Be Published
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8GA0
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![BU of 8ga0 by Molmil](/molmil-images/mine/8ga0) | CLC-ec1 E202Y at pH 4.5 100mM Cl Turn | Descriptor: | H(+)/Cl(-) exchange transporter ClcA | Authors: | Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. | Deposit date: | 2023-02-22 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
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8GAH
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![BU of 8gah by Molmil](/molmil-images/mine/8gah) | CLC-ec1 L25C/A450C/C85A at pH 4.5 100mM Cl Twist | Descriptor: | CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA | Authors: | Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. | Deposit date: | 2023-02-22 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
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8GA3
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![BU of 8ga3 by Molmil](/molmil-images/mine/8ga3) | CLC-ec1 R230C/L249C/C85A at pH 4.5 100mM Cl Turn | Descriptor: | CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA | Authors: | Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. | Deposit date: | 2023-02-22 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
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8GA1
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![BU of 8ga1 by Molmil](/molmil-images/mine/8ga1) | CLC-ec1 R230C/L249C/C85A at pH 4.5 100mM Cl Swap | Descriptor: | CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA | Authors: | Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. | Deposit date: | 2023-02-22 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
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8GA5
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![BU of 8ga5 by Molmil](/molmil-images/mine/8ga5) | CLC-ec1 L25C/A450C/C85A at pH 4.5 100mM Cl Intermediate | Descriptor: | CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA | Authors: | Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. | Deposit date: | 2023-02-22 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
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7RNX
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![BU of 7rnx by Molmil](/molmil-images/mine/7rnx) | CLC-ec1 at pH 7.5 100mM Cl Swap | Descriptor: | H(+)/Cl(-) exchange transporter ClcA | Authors: | Fortea, E, Boudker, O, Accardi, A. | Deposit date: | 2021-07-30 | Release date: | 2022-11-16 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Structural basis of common gate activation in CLC transporters To Be Published
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7RP6
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![BU of 7rp6 by Molmil](/molmil-images/mine/7rp6) | |
7RO0
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![BU of 7ro0 by Molmil](/molmil-images/mine/7ro0) | |
7RSB
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![BU of 7rsb by Molmil](/molmil-images/mine/7rsb) | |
7RP5
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![BU of 7rp5 by Molmil](/molmil-images/mine/7rp5) | CLC-ec1 at pH 4.5 100mM Cl Turn | Descriptor: | H(+)/Cl(-) exchange transporter ClcA | Authors: | Fortea, E, Boudker, O, Accardi, A. | Deposit date: | 2021-08-03 | Release date: | 2022-11-16 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Structural basis of common gate activation in CLC transporters To Be Published
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7RQ7
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![BU of 7rq7 by Molmil](/molmil-images/mine/7rq7) | |
6X2L
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![BU of 6x2l by Molmil](/molmil-images/mine/6x2l) | hEAAT3-IFS-Na | Descriptor: | Excitatory amino acid transporter 3 | Authors: | Qiu, B, Matthies, D, Boudker, O. | Deposit date: | 2020-05-20 | Release date: | 2021-03-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport. Sci Adv, 7, 2021
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6X2Z
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![BU of 6x2z by Molmil](/molmil-images/mine/6x2z) | hEAAT3-OFS-Asp | Descriptor: | ASPARTIC ACID, Excitatory amino acid transporter 3, SODIUM ION | Authors: | Qiu, B, Matthies, D, Boudker, O. | Deposit date: | 2020-05-21 | Release date: | 2021-03-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport. Sci Adv, 7, 2021
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6X3E
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![BU of 6x3e by Molmil](/molmil-images/mine/6x3e) | hEAAT3-Asymmetric-1o2i | Descriptor: | ASPARTIC ACID, Excitatory amino acid transporter 3, SODIUM ION | Authors: | Qiu, B, Matthies, D, Boudker, O. | Deposit date: | 2020-05-21 | Release date: | 2021-03-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport. Sci Adv, 7, 2021
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6X3F
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![BU of 6x3f by Molmil](/molmil-images/mine/6x3f) | hEAAT3-IFS-Apo | Descriptor: | CHOLINE ION, Excitatory amino acid transporter 3 | Authors: | Qiu, B, Matthies, D, Boudker, O. | Deposit date: | 2020-05-21 | Release date: | 2021-03-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport. Sci Adv, 7, 2021
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7RX2
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![BU of 7rx2 by Molmil](/molmil-images/mine/7rx2) | |
7RXA
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![BU of 7rxa by Molmil](/molmil-images/mine/7rxa) | afTMEM16 DE/AA mutant in C14 lipid nanodiscs in the presence of Ca2+ | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase | Authors: | Feng, Z, Accardi, A. | Deposit date: | 2021-08-22 | Release date: | 2022-05-18 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | TMEM16 scramblases thin the membrane to enable lipid scrambling. Nat Commun, 13, 2022
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7RXH
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![BU of 7rxh by Molmil](/molmil-images/mine/7rxh) | |
7RXB
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![BU of 7rxb by Molmil](/molmil-images/mine/7rxb) | afTMEM16 lipid scramblase in C18 lipid nanodiscs in the absence of Ca2+ | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase | Authors: | Feng, Z, Accardi, A. | Deposit date: | 2021-08-22 | Release date: | 2022-05-18 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | TMEM16 scramblases thin the membrane to enable lipid scrambling. Nat Commun, 13, 2022
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7RX3
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![BU of 7rx3 by Molmil](/molmil-images/mine/7rx3) | |
7RXG
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![BU of 7rxg by Molmil](/molmil-images/mine/7rxg) | |
7RWJ
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![BU of 7rwj by Molmil](/molmil-images/mine/7rwj) | |