1AFX
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![BU of 1afx by Molmil](/molmil-images/mine/1afx) | |
1B36
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![BU of 1b36 by Molmil](/molmil-images/mine/1b36) | |
1TLR
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![BU of 1tlr by Molmil](/molmil-images/mine/1tlr) | |
4N0T
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![BU of 4n0t by Molmil](/molmil-images/mine/4n0t) | Core structure of the U6 small nuclear ribonucleoprotein at 1.7 Angstrom resolution | Descriptor: | SULFATE ION, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA | Authors: | Montemayor, E.J, Curran, E.C, Liao, H, Andrews, K.L, Treba, C.N, Butcher, S.E, Brow, D.A. | Deposit date: | 2013-10-02 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Core structure of the U6 small nuclear ribonucleoprotein at 1.7- angstrom resolution. Nat.Struct.Mol.Biol., 21, 2014
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8TNS
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![BU of 8tns by Molmil](/molmil-images/mine/8tns) | |
6E7L
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![BU of 6e7l by Molmil](/molmil-images/mine/6e7l) | Structure of a dimerized UUCG motif | Descriptor: | RNA (5'-R(*GP*GP*GP*CP*UP*GP*CP*AP*CP*UP*UP*CP*GP*GP*UP*GP*CP*UP*GP*CP*CP*C)-3') | Authors: | Montemayor, E.J, Butcher, S.E. | Deposit date: | 2018-07-26 | Release date: | 2019-07-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structure of an RNA helix with pyrimidine mismatches and cross-strand stacking. Acta Crystallogr.,Sect.F, 75, 2019
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5V1M
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![BU of 5v1m by Molmil](/molmil-images/mine/5v1m) | Structure of human Usb1 with uridine 5'-monophosphate | Descriptor: | CHLORIDE ION, GLYCEROL, U6 snRNA phosphodiesterase, ... | Authors: | Montemayor, E.J, Didychuk, A.L, Butcher, S.E. | Deposit date: | 2017-03-02 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities. Nat Commun, 8, 2017
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5UQJ
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![BU of 5uqj by Molmil](/molmil-images/mine/5uqj) | Structure of yeast Usb1 | Descriptor: | ACETATE ION, GLYCEROL, SULFATE ION, ... | Authors: | Didychuk, A.L, Montemayor, E.J, Butcher, S.E. | Deposit date: | 2017-02-08 | Release date: | 2017-08-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities. Nat Commun, 8, 2017
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7MKT
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![BU of 7mkt by Molmil](/molmil-images/mine/7mkt) | Crystal structure of r(GU)11G-NMM complex | Descriptor: | N-METHYLMESOPORPHYRIN, POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3') | Authors: | Bingman, C.A, Roschdi, S, Nomura, Y, Butcher, S.E. | Deposit date: | 2021-04-26 | Release date: | 2022-11-02 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | An atypical RNA quadruplex marks RNAs as vectors for gene silencing. Nat.Struct.Mol.Biol., 29, 2022
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1XHP
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![BU of 1xhp by Molmil](/molmil-images/mine/1xhp) | |
1Z2J
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![BU of 1z2j by Molmil](/molmil-images/mine/1z2j) | |
2ADT
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![BU of 2adt by Molmil](/molmil-images/mine/2adt) | NMR structure of a 30 kDa GAAA tetraloop-receptor complex. | Descriptor: | 43-MER | Authors: | Davis, J.H, Tonelli, M, Scott, L.G, Jaeger, L, Williamson, J.R, Butcher, S.E. | Deposit date: | 2005-07-20 | Release date: | 2005-07-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | RNA Helical Packing in Solution: NMR Structure of a 30 kDa GAAA Tetraloop-Receptor Complex J.Mol.Biol., 351, 2005
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5TF6
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![BU of 5tf6 by Molmil](/molmil-images/mine/5tf6) | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core | Descriptor: | CHLORIDE ION, GLYCEROL, POTASSIUM ION, ... | Authors: | Montemayor, E.J, Brow, D.A, Butcher, S.E. | Deposit date: | 2016-09-24 | Release date: | 2017-01-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core. Acta Crystallogr D Struct Biol, 73, 2017
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2L94
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![BU of 2l94 by Molmil](/molmil-images/mine/2l94) | Structure of the HIV-1 frameshift site RNA bound to a small molecule inhibitor of viral replication | Descriptor: | N'-{(Z)-amino[4-(amino{[3-(dimethylammonio)propyl]iminio}methyl)phenyl]methylidene}-N,N-dimethylpropane-1,3-diaminium, RNA_(45-MER) | Authors: | Marcheschi, R.J, Tonelli, M, Kumar, A, Butcher, S.E. | Deposit date: | 2011-01-29 | Release date: | 2011-06-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the HIV-1 Frameshift Site RNA Bound to a Small Molecule Inhibitor of Viral Replication. Acs Chem.Biol., 6, 2011
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2N7M
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![BU of 2n7m by Molmil](/molmil-images/mine/2n7m) | NMR-SAXS/WAXS Structure of the core of the U4/U6 di-snRNA | Descriptor: | RNA (92-MER) | Authors: | Cornilescu, G, Didychuk, A.L, Rodgers, M.L, Michael, L.A, Burke, J.E, Montemayor, E.J, Hoskins, A.A, Butcher, S.E, Tonelli, M. | Deposit date: | 2015-09-14 | Release date: | 2015-12-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Analysis of Multi-Helical RNAs by NMR-SAXS/WAXS: Application to the U4/U6 di-snRNA. J.Mol.Biol., 428, 2016
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2O32
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![BU of 2o32 by Molmil](/molmil-images/mine/2o32) | Solution structure of U2 snRNA stem I from human, containing modified nucleotides | Descriptor: | 5'-R(*(PSU)P*CP*UP*CP*(OMG)P*(OMG)P*CP*CP*(PSU)P*UP*UP*UP*(OMG)P*GP*CP*UP*AP*AP*(OMG)P*A)-3' | Authors: | Sashital, D.G, Venditti, V, Angers, C.G, Cornilescu, G, Butcher, S.E. | Deposit date: | 2006-11-30 | Release date: | 2007-02-06 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure and thermodynamics of a conserved U2 snRNA domain from yeast and human. Rna, 13, 2007
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2O33
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![BU of 2o33 by Molmil](/molmil-images/mine/2o33) | Solution structure of U2 snRNA stem I from S. cerevisiae | Descriptor: | U2 snRNA | Authors: | Sashital, D.G, Venditti, V, Angers, C.A, Cornilescu, G, Butcher, S.E. | Deposit date: | 2006-11-30 | Release date: | 2007-02-06 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure and thermodynamics of a conserved U2 snRNA domain from yeast and human. Rna, 13, 2007
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2N8V
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![BU of 2n8v by Molmil](/molmil-images/mine/2n8v) | An NMR/SAXS structure of the PKI domain of the honeybee dicistrovirus, Israeli acute paralysis virus (IAPV) IRES | Descriptor: | RNA (70-MER) | Authors: | Au, H.H, Cornilescu, G, Mouzakis, K.D, Burke, J.E, Ren, Q, Lee, S, Butcher, S.E, Jan, E. | Deposit date: | 2015-10-27 | Release date: | 2015-11-11 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Global shape mimicry of tRNA within a viral internal ribosome entry site mediates translational reading frame selection. Proc.Natl.Acad.Sci.USA, 112, 2015
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2KEZ
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![BU of 2kez by Molmil](/molmil-images/mine/2kez) | NMR structure of U6 ISL at pH 8.0 | Descriptor: | RNA (5'-R(*GP*GP*UP*UP*CP*CP*CP*CP*UP*GP*CP*AP*UP*AP*AP*GP*GP*AP*UP*GP*AP*AP*CP*C)-3') | Authors: | Venditti, V, Butcher, S.E. | Deposit date: | 2009-02-08 | Release date: | 2009-07-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Minimum-energy path for a u6 RNA conformational change involving protonation, base-pair rearrangement and base flipping. J.Mol.Biol., 391, 2009
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2KF0
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![BU of 2kf0 by Molmil](/molmil-images/mine/2kf0) | NMR structure of U6 ISL at pH 7.0 | Descriptor: | RNA (5'-R(*GP*GP*UP*UP*CP*CP*CP*CP*UP*GP*CP*AP*UP*AP*AP*GP*GP*AP*UP*GP*AP*AP*CP*C)-3') | Authors: | Venditti, V, Butcher, S.E. | Deposit date: | 2009-02-08 | Release date: | 2009-07-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Minimum-energy path for a u6 RNA conformational change involving protonation, base-pair rearrangement and base flipping. J.Mol.Biol., 391, 2009
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1SYZ
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![BU of 1syz by Molmil](/molmil-images/mine/1syz) | |
1SY4
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![BU of 1sy4 by Molmil](/molmil-images/mine/1sy4) | Refined solution structure of the S. cerevisiae U6 INTRAMOLECULAR STEM LOOP (ISL) RNA USING RESIDUAL DIPOLAR COUPLINGS (RDCS) | Descriptor: | U6 Intramolecular Stem-Loop RNA | Authors: | Reiter, N.J, Nikstad, L.J, Allman, A.M, Johnson, R.J, Butcher, S.E. | Deposit date: | 2004-03-31 | Release date: | 2004-04-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the U6 RNA intramolecular stem-loop harboring an
S(P)-phosphorothioate modification. RNA, 9, 2003
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1PJY
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![BU of 1pjy by Molmil](/molmil-images/mine/1pjy) | |
1NC0
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![BU of 1nc0 by Molmil](/molmil-images/mine/1nc0) | |
1NZ1
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![BU of 1nz1 by Molmil](/molmil-images/mine/1nz1) | Solution structure of the S. cerevisiae U6 Intramolecular stem-loop containing an SP phosphorothioate at nucleotide U80 | Descriptor: | SP U6 Intramolecular Stem-Loop RNA | Authors: | Reiter, N.J, Nikstad, L.J, Allman, A.M, Johnson, R.J, Butcher, S.E. | Deposit date: | 2003-02-14 | Release date: | 2003-05-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the U6 RNA intramolecular stem-loop harboring an
S(P)-phosphorothioate modification. RNA, 9, 2003
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