2F89
 
 | | Crystal structure of human FPPS in complex with pamidronate | | Descriptor: | Farnesyl Diphosphate Synthase, MANGANESE (II) ION, PAMIDRONATE, ... | | Authors: | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | | Deposit date: | 2005-12-02 | | Release date: | 2006-02-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
Chemmedchem, 1, 2006
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2F8Z
 | | Crystal structure of human FPPS in complex with zoledronate and isopentenyl diphosphate | | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl Diphosphate Synthase, MAGNESIUM ION, ... | | Authors: | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | | Deposit date: | 2005-12-02 | | Release date: | 2006-02-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
Chemmedchem, 1, 2006
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2F94
 | | Crystal structure of human FPPS in complex with ibandronate | | Descriptor: | Farnesyl Diphosphate Synthase, IBANDRONATE, PHOSPHATE ION, ... | | Authors: | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | | Deposit date: | 2005-12-05 | | Release date: | 2006-02-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
Chemmedchem, 1, 2006
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2FAZ
 | | Ubiquitin-Like Domain of Human Nuclear Zinc Finger Protein NP95 | | Descriptor: | Ubiquitin-like containing PHD and RING finger domains protein 1 | | Authors: | Walker, J.R, Wybenga-Groot, L, Doherty, R.S, Finerty Jr, P.J, Newman, E, Mackenzie, F.M, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2005-12-08 | | Release date: | 2005-12-20 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Ubiquitin-Like Domain of Human Nuclear Zinc Finger Protein NP95
To be Published
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2L09
 | | Solution NMR Structure of Protein asr4154 from Nostoc sp. PCC7120 Northeast Structural Genomics Consortium target ID NsR143 | | Descriptor: | Asr4154 protein | | Authors: | Feldmann, E.A, Yang, Y.A, Ramelot, T.A, Cort, J.R, Janjua, H, Ciccosanti, C.A, Lee, D, Acton, T.B, Xiao, R.A, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-06-30 | | Release date: | 2010-08-25 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR Solution Structure of asr4154 from Nostoc sp. PCC7120 Northeast Structural Genomics target ID Nsr143
To be Published
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2EZD
 | | SOLUTION STRUCTURE OF A COMPLEX OF THE SECOND DNA BINDING DOMAIN OF HUMAN HMG-I(Y) BOUND TO DNA DODECAMER CONTAINING THE PRDII SITE OF THE INTERFERON-BETA PROMOTER, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | DNA (5'-D(*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3'), HIGH MOBILITY GROUP PROTEIN HMG-I/HMG-Y | | Authors: | Clore, G.M, Huth, J.R, Bewley, C, Gronenborn, A.M. | | Deposit date: | 1997-06-04 | | Release date: | 1997-10-15 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The solution structure of an HMG-I(Y)-DNA complex defines a new architectural minor groove binding motif.
Nat.Struct.Biol., 4, 1997
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2L8P
 | | Solution Structure of a DNA Duplex Containing the Potent Anti-Poxvirus Agent Cidofovir | | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*TP*GP*(L8P)P*TP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*AP*GP*CP*AP*TP*GP*CP*G)-3') | | Authors: | Julien, O, Beadle, J.R, Magee, W.C, Chatterjee, S, Hostetler, K.Y, Evans, D.H, Sykes, B.D. | | Deposit date: | 2011-01-22 | | Release date: | 2011-02-23 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir.
J.Am.Chem.Soc., 133, 2011
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2L8T
 | | Staphylococcus aureus pathogenicity island 1 protein gp6, an internal scaffold in size determination | | Descriptor: | Transposon Tn557 toxic shock syndrome toxin-1 | | Authors: | Dearborn, A.D, Spilman, M.S, Damle, P.K, Chang, J.R, Monroe, E.B, Saad, J.S, Christie, G.E, Dokland, T. | | Deposit date: | 2011-01-24 | | Release date: | 2011-08-17 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The Staphylococcus aureus Pathogenicity Island 1 Protein gp6 Functions as an Internal Scaffold during Capsid Size Determination.
J.Mol.Biol., 412, 2011
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2GM2
 | | NMR structure of Xanthomonas campestris XCC1710: Northeast Structural Genomics Consortium target XcR35 | | Descriptor: | conserved hypothetical protein | | Authors: | Cort, J.R, Xiao, R, Wang, D.Y, Ma, L.C, Ciano, M, Montelione, G.T, Ramelot, T.A, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-04-05 | | Release date: | 2006-04-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | NMR structure of Xanthomonas campestris XCC1710 protein
To be Published
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2LK2
 | | Solution NMR structure of homeobox domain (171-248) of human homeobox protein TGIF1, Northeast Structural Genomics Consortium Target HR4411B | | Descriptor: | Homeobox protein TGIF1 | | Authors: | Yang, Y, Ramelot, T.A, Cort, J.R, Shastry, R, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-09-30 | | Release date: | 2011-10-26 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of homeobox domain (171-248) of human homeobox protein TGIF1, Northeast Structural Genomics Consortium Target HR4411B.
To be Published
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2HAC
 | | Structure of Zeta-Zeta Transmembrane Dimer | | Descriptor: | T-cell surface glycoprotein CD3 zeta chain | | Authors: | Chou, J.J, Wucherpfennig, K.W, Schnell, J.R, Call, M.E. | | Deposit date: | 2006-06-12 | | Release date: | 2006-10-31 | | Last modified: | 2021-10-20 | | Method: | SOLUTION NMR | | Cite: | The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor.
Cell(Cambridge,Mass.), 127, 2006
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2GBS
 | | NMR structure of Rpa0253 from Rhodopseudomonas palustris. Northeast structural genomics consortium target RpR3 | | Descriptor: | Hypothetical protein Rpa0253 | | Authors: | Ramelot, T.A, Cort, J.R, Conover, K, Chen, Y, Ma, L.C, Ciano, M, Xiao, R, Acton, T.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-03-11 | | Release date: | 2006-04-11 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural genomics reveals EVE as a new ASCH/PUA-related domain.
Proteins, 75, 2009
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2G3R
 | | Crystal Structure of 53BP1 tandem tudor domains at 1.2 A resolution | | Descriptor: | SULFATE ION, Tumor suppressor p53-binding protein 1 | | Authors: | Lee, J, Botuyan, M.V, Thompson, J.R, Mer, G. | | Deposit date: | 2006-02-20 | | Release date: | 2007-01-02 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair.
Cell(Cambridge,Mass.), 127, 2006
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2FXF
 | | Human spermidine/spermine N1-acetyltransferase | | Descriptor: | ACETATE ION, ACETYL COENZYME *A, CALCIUM ION, ... | | Authors: | Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-02-05 | | Release date: | 2006-02-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Crystal Structure of Human spermidine/spermine
N1-acetyltransferase
To be Published
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2G7Y
 | | Human Cathepsin S with inhibitor CRA-16981 | | Descriptor: | (1R)-2-[(CYANOMETHYL)AMINO]-1-({[2-(DIFLUOROMETHOXY)BENZYL]SULFONYL}METHYL)-2-OXOETHYL MORPHOLINE-4-CARBOXYLATE, Cathepsin S | | Authors: | Somoza, J.R. | | Deposit date: | 2006-03-01 | | Release date: | 2006-09-05 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Human Cathepsin S with inhibitor CRA-16981
To be Published
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2H6D
 | | Protein Kinase Domain of the Human 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK alpha-2 chain) | | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | | Authors: | Littler, D.R, Walker, J.R, Wybenga-Groot, L, Newman, E.M, Butler-Cole, C, Mackenzie, F, Finerty, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-05-31 | | Release date: | 2006-06-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.
Acta Crystallogr.,Sect.F, 66, 2010
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2HEQ
 | | NMR Structure of Bacillus subtilis protein YorP, Northeast Structural Genomics Target SR399. | | Descriptor: | YorP protein | | Authors: | Ramelot, T.A, Cort, J.R, Wang, D, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.M, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-06-21 | | Release date: | 2006-08-15 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | NMR Structure of Bacillus subtilis protein YorP, Northeast Structural Genomics Target SR399.
To be Published
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2HE9
 | | Structure of the peptidylprolyl isomerase domain of the human NK-tumour recognition protein | | Descriptor: | NK-tumor recognition protein, SULFATE ION | | Authors: | Walker, J.R, Davis, T, Newman, E.M, MacKenzie, F, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-06-21 | | Release date: | 2006-07-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.
PLoS Biol., 8, 2010
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2F9K
 | | Crystal structure of human FPPS in complex with Zoledronate and Zn2+ | | Descriptor: | Farnesyl Diphosphate Synthase, PHOSPHATE ION, ZINC ION, ... | | Authors: | Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. | | Deposit date: | 2005-12-06 | | Release date: | 2006-02-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
Chemmedchem, 1, 2006
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2FHD
 | | Crystal structure of Crb2 tandem tudor domains | | Descriptor: | DNA repair protein rhp9/CRB2, PHOSPHATE ION | | Authors: | Lee, J, Botuyan, M.V, Thompson, J.R, Mer, G. | | Deposit date: | 2005-12-23 | | Release date: | 2007-01-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.
Cell(Cambridge,Mass.), 127, 2006
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2O9U
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2HGK
 | | Solution NMR Structure of protein YqcC from E. coli: Northeast Structural Genomics Consortium target ER225 | | Descriptor: | Hypothetical protein yqcC | | Authors: | Cort, J.R, Wang, D, Shetty, K, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-06-27 | | Release date: | 2007-06-05 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | NMR structure of protein YqcC from E.coli
To be Published
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2KJR
 | | Solution NMR structure of the N-terminal Ubiquitin-like Domain from Tubulin-binding Cofactor B, CG11242, from Drosophila melanogaster. Northeast Structural Genomics Consortium Target FR629A (residues 8-92) | | Descriptor: | CG11242 | | Authors: | Ramelot, T.A, Cort, J.R, Shastry, R, Ciccosanti, C, Jiang, M, Nair, R, Rost, B, Swapna, G, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-06-08 | | Release date: | 2009-06-23 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the N-terminal Ubiquitin-like Domain from
Tubulin-binding Cofactor B, CG11242, from Drosophila melanogaster. Northeast
Structural Genomics Consortium Target FR629A (residues 8-92)
To be Published
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2K4Z
 | | Solution NMR Structure of Allochromatium vinosum DsrR: Northeast Structural Genomics Consortium Target OP5 | | Descriptor: | DsrR | | Authors: | Cort, J.R, Dahl, C, Grimm, F, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-06-22 | | Release date: | 2008-07-22 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of the IscA-like Protein DsrR Involved in Sulfur Oxidation in Allochromatium vinosum
To be Published
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2HH8
 | | Solution NMR structure of the ydfO protein from Escherichia coli. Northeast Structural Genomics target ER251. | | Descriptor: | Hypothetical protein ydfO | | Authors: | Rossi, P, Cort, J.R, Ho, C.K, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-06-28 | | Release date: | 2006-08-22 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the ydfO protein from Escherichia coli. Northeast Structural Genomics target ER251.
To be Published
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