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5X56
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BU of 5x56 by Molmil
Crystal structure of PSB27 from Arabidopsis thaliana
Descriptor: Photosystem II repair protein PSB27-H1, chloroplastic
Authors:Liu, J, Cheng, X.
Deposit date:2017-02-15
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of Psb27 from Arabidopsis thaliana determined at a resolution of 1.85 angstrom.
Photosyn. Res., 136, 2018
4DN5
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BU of 4dn5 by Molmil
Crystal Structure of NF-kB-inducing Kinase (NIK)
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ...
Authors:Min, X, Liu, J, Sudom, A, Walker, N.P, Wang, Z.
Deposit date:2012-02-08
Release date:2012-06-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Nuclear Factor Kappa B-inducing kinase domain reveals a constitutively active conformation
J.Biol.Chem., 287, 2012
3VBV
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BU of 3vbv by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 8-hydroxyquinoline-2-carboxamide, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VBQ
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BU of 3vbq by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: (5~{Z})-5-[[3-[6-[(4-azanylcyclohexyl)amino]pyrazin-2-yl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VBY
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BU of 3vby by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: IMIDAZOLE, Serine/threonine-protein kinase pim-1, furan-2-yl(1H-indol-3-yl)methanone
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
4F0I
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BU of 4f0i by Molmil
Crystal structure of apo TrkA
Descriptor: High affinity nerve growth factor receptor
Authors:Liu, J.
Deposit date:2012-05-04
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:The Crystal Structures of TrkA and TrkB Suggest Key Regions for Achieving Selective Inhibition.
J.Mol.Biol., 423, 2012
3VBW
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BU of 3vbw by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 1,3-dioxo-2,3-dihydro-1H-indene-2-carbonitrile, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VBX
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BU of 3vbx by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 6-bromo-4-hydroxy-2H-chromen-2-one, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VC4
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BU of 3vc4 by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: (5Z)-5-[3-(trifluoromethyl)benzylidene]-1,3-thiazolidine-2,4-dione, IMIDAZOLE, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-03
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VBT
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BU of 3vbt by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 4-chloro-2-(1H-pyrazol-3-yl)phenol, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
2NRN
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BU of 2nrn by Molmil
Self-assembly of coiled-coil tetramers in the 1.40 A structure of a leucine-zipper mutant
Descriptor: General control protein GCN4, PHOSPHATE ION
Authors:Liu, J, Lu, M.
Deposit date:2006-11-02
Release date:2007-04-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Self-assembly of coiled-coil tetramers in the 1.40 A structure of a leucine-zipper mutant.
Protein Sci., 16, 2007
7E35
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BU of 7e35 by Molmil
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant bound to compound S43
Descriptor: N-[(3-acetamidophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Non-structural protein 3, ZINC ION
Authors:Liu, J, Wang, Y, Xu, X, Pan, L.
Deposit date:2021-02-08
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Cell Chem Biol, 28, 2021
7D6H
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BU of 7d6h by Molmil
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant
Descriptor: PHOSPHATE ION, Papain-like protease, ZINC ION
Authors:Liu, J, Wang, Y, Pan, L.
Deposit date:2020-09-30
Release date:2020-11-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Cell Chem Biol, 28, 2021
4USG
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BU of 4usg by Molmil
Crystal structure of PC4 W89Y mutant complex with DNA
Descriptor: 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP *TP*TP*TP*TP*TP*G)-3', ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15
Authors:Zhao, Y, Liu, J.
Deposit date:2014-07-08
Release date:2015-03-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.973 Å)
Cite:Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4.
Sci.Rep., 5, 2015
2W4V
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BU of 2w4v by Molmil
Isometrically contracting insect asynchronous flight muscle quick frozen after a quick release step
Descriptor: MYOSIN ESSENTIAL LIGHT CHAIN, STRIATED ADDUCTOR MUSCLE, MYOSIN HEAVY CHAIN, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-12-02
Release date:2010-09-15
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
2W4A
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BU of 2w4a by Molmil
ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE
Descriptor: MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-11-24
Release date:2010-04-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
2W4H
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BU of 2w4h by Molmil
Isometrically contracting insect asynchronous flight muscle quick frozen after a quick release step
Descriptor: MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-11-25
Release date:2010-08-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
2W4G
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BU of 2w4g by Molmil
ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE QUICK FROZEN AFTER A QUICK STRETCH STEP
Descriptor: MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-11-25
Release date:2010-08-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
2W4T
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BU of 2w4t by Molmil
ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE
Descriptor: MYOSIN ESSENTIAL LIGHT CHAIN, STRIATED ADDUCTOR MUSCLE, MYOSIN HEAVY CHAIN, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-12-02
Release date:2010-01-19
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
2W49
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BU of 2w49 by Molmil
ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE
Descriptor: ACTIN, ALPHA SKELETAL MUSCLE, CALCIUM ION, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-11-24
Release date:2010-05-05
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
2W4U
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BU of 2w4u by Molmil
Isometrically contracting insect asynchronous flight muscle quick frozen after a length step
Descriptor: ACTIN, ALPHA SKELETAL MUSCLE, TROPOMYOSIN ALPHA-1 CHAIN, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-12-02
Release date:2010-08-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
2W4W
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BU of 2w4w by Molmil
Isometrically contracting insect asynchronous flight muscle quick frozen after a quick stretch step
Descriptor: MYOSIN ESSENTIAL LIGHT CHAIN, STRIATED ADDUCTOR MUSCLE, MYOSIN HEAVY CHAIN, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-12-02
Release date:2010-08-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
2I7K
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BU of 2i7k by Molmil
Solution Structure of the Bromodomain of Human BRD7 Protein
Descriptor: Bromodomain-containing protein 7
Authors:Sun, H, Liu, J, Zhang, J, Huang, H, Wu, J, Shi, Y.
Deposit date:2006-08-31
Release date:2007-07-10
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4
Biochem.Biophys.Res.Commun., 358, 2007
3ERJ
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BU of 3erj by Molmil
Crystal structure of the peptidyl-tRNA hydrolase AF2095 from Archaeglobus fulgidis. Northeast Structural Genomics Consortium target GR4
Descriptor: Peptidyl-tRNA hydrolase
Authors:Forouhar, F, Su, M, Seetharaman, J, Conover, K, Janjua, H, Xiao, R, Cunningham, K, Ma, L.-C, Cooper, B, Baran, M.C, Liu, J, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-10-02
Release date:2008-10-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the peptidyl-tRNA hydrolase AF2095 from Archaeglobus fulgidis. Northeast Structural Genomics Consortium target GR4
To be Published
3E5Z
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BU of 3e5z by Molmil
X-Ray structure of the putative gluconolactonase in protein family PF08450. Northeast Structural Genomics Consortium target DrR130.
Descriptor: MAGNESIUM ION, putative Gluconolactonase
Authors:Kuzin, A.P, Abashidze, M, Seetharaman, J, Wang, D, Mao, L, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Tong, S.N, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-08-14
Release date:2008-09-30
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:X-Ray structure of the putative gluconolactonase in protein family PF08450. Northeast Structural Genomics Consortium target DrR130.
To be Published

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數據於2024-07-24公開中

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