1KY4
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1KY5
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![BU of 1ky5 by Molmil](/molmil-images/mine/1ky5) | D244E mutant S-Adenosylhomocysteine hydrolase refined with noncrystallographic restraints | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3'-OXO-ADENOSINE, S-adenosylhomocysteine hydrolase | Authors: | Takata, Y, Takusagawa, F. | Deposit date: | 2002-02-03 | Release date: | 2002-09-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Catalytic Mechanism of S-adenosylhomocysteine hydrolase. Site-directed
mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190. J.Biol.Chem., 277, 2002
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7PY2
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![BU of 7py2 by Molmil](/molmil-images/mine/7py2) | Structure of pathological TDP-43 filaments from ALS with FTLD | Descriptor: | TAR DNA-binding protein 43 | Authors: | Arseni, D, Hasegawa, H, Murzin, A.G, Kametani, F, Arai, M, Yoshida, M, Falcon, B. | Deposit date: | 2021-10-08 | Release date: | 2021-12-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Structure of pathological TDP-43 filaments from ALS with FTLD. Nature, 601, 2022
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1HJR
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5JH9
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![BU of 5jh9 by Molmil](/molmil-images/mine/5jh9) | Crystal structure of prApe1 | Descriptor: | CACODYLATE ION, Vacuolar aminopeptidase 1, ZINC ION | Authors: | Noda, N.N, Adachi, W, Inagaki, F. | Deposit date: | 2016-04-20 | Release date: | 2016-06-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates Cell Rep, 16, 2016
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5JGF
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![BU of 5jgf by Molmil](/molmil-images/mine/5jgf) | Crystal structure of mApe1 | Descriptor: | Vacuolar aminopeptidase 1, ZINC ION | Authors: | Noda, N.N, Adachi, W, Inagaki, F. | Deposit date: | 2016-04-20 | Release date: | 2016-06-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates Cell Rep, 16, 2016
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5JHC
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5JGE
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1NBI
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1KMF
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![BU of 1kmf by Molmil](/molmil-images/mine/1kmf) | NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALLO-ILE, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES | Descriptor: | Insulin | Authors: | Xu, B, Hua, Q.X, Nakagawa, S.H, Jia, W, Chu, Y.C, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 2001-12-14 | Release date: | 2002-01-09 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue. J.Mol.Biol., 316, 2002
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1NBH
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1KHH
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7BRN
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![BU of 7brn by Molmil](/molmil-images/mine/7brn) | Crystal structure of Atg40 AIM fused to Atg8 | Descriptor: | 1,2-ETHANEDIOL, Autophagy-related protein 40,Autophagy-related protein 8, L-EPINEPHRINE | Authors: | Yamasaki, A, Noda, N.N. | Deposit date: | 2020-03-29 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.231 Å) | Cite: | Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes. Nat Commun, 11, 2020
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7BRQ
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![BU of 7brq by Molmil](/molmil-images/mine/7brq) | Crystal structure of human FAM134B LIR fused to human GABARAP | Descriptor: | GLYCEROL, Reticulophagy regulator 1,Gamma-aminobutyric acid receptor-associated protein | Authors: | Yamasaki, A, Noda, N.N. | Deposit date: | 2020-03-29 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.404 Å) | Cite: | Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes. Nat Commun, 11, 2020
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7BRT
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![BU of 7brt by Molmil](/molmil-images/mine/7brt) | Crystal structure of Sec62 LIR fused to GABARAP | Descriptor: | Translocation protein SEC62,Gamma-aminobutyric acid receptor-associated protein | Authors: | Yamasaki, A, Noda, N.N. | Deposit date: | 2020-03-30 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes. Nat Commun, 11, 2020
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7BRU
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![BU of 7bru by Molmil](/molmil-images/mine/7bru) | Crystal structure of human RTN3 LIR fused to human GABARAP | Descriptor: | PHOSPHATE ION, Reticulon-3,Gamma-aminobutyric acid receptor-associated protein | Authors: | Yamasaki, A, Noda, N.N. | Deposit date: | 2020-03-30 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.149 Å) | Cite: | Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes. Nat Commun, 11, 2020
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1D2C
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![BU of 1d2c by Molmil](/molmil-images/mine/1d2c) | METHYLTRANSFERASE | Descriptor: | PROTEIN (GLYCINE N-METHYLTRANSFERASE) | Authors: | Huang, Y, Takusagawa, F. | Deposit date: | 1999-09-23 | Release date: | 1999-10-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes. J.Mol.Biol., 298, 2000
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5H4S
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1P1C
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![BU of 1p1c by Molmil](/molmil-images/mine/1p1c) | Guanidinoacetate Methyltransferase with Gd ion | Descriptor: | GADOLINIUM ION, Guanidinoacetate N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Komoto, J, Takusagawa, F. | Deposit date: | 2003-04-12 | Release date: | 2003-04-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Monoclinic guanidinoacetate methyltransferase and gadolinium ion-binding characteristics. Acta Crystallogr.,Sect.D, 59, 2003
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1D2H
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![BU of 1d2h by Molmil](/molmil-images/mine/1d2h) | CRYSTAL STRUCTURE OF R175K MUTANT GLYCINE N-METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYLHOMOCYSTEINE | Descriptor: | GLYCINE N-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Huang, Y, Komoto, J, Takusagawa, F, Konishi, K, Takata, Y. | Deposit date: | 1999-10-11 | Release date: | 1999-10-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes. J.Mol.Biol., 298, 2000
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1D2G
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![BU of 1d2g by Molmil](/molmil-images/mine/1d2g) | CRYSTAL STRUCTURE OF R175K MUTANT GLYCINE N-METHYLTRANSFERASE FROM RAT LIVER | Descriptor: | GLYCINE N-METHYLTRANSFERASE | Authors: | Huang, Y, Komoto, J, Takusagawa, F, Konishi, K, Takata, Y. | Deposit date: | 1999-10-08 | Release date: | 1999-10-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes. J.Mol.Biol., 298, 2000
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1P1B
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![BU of 1p1b by Molmil](/molmil-images/mine/1p1b) | Guanidinoacetate methyltransferase | Descriptor: | Guanidinoacetate N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Komoto, J, Takusagawa, F. | Deposit date: | 2003-04-12 | Release date: | 2003-04-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Monoclinic guanidinoacetate methyltransferase and gadolinium ion-binding characteristics. Acta Crystallogr.,Sect.D, 59, 2003
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5F9E
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![BU of 5f9e by Molmil](/molmil-images/mine/5f9e) | Structure of Protein Kinase C theta with compound 10: 2,2-dimethyl-7-(2-oxidanylidene-3~{H}-imidazo[4,5-b]pyridin-1-yl)-1-(phenylmethyl)-3~{H}-quinazolin-4-one | Descriptor: | 2,2-dimethyl-7-(2-oxidanylidene-3~{H}-imidazo[4,5-b]pyridin-1-yl)-1-(phenylmethyl)-3~{H}-quinazolin-4-one, Protein kinase C theta type | Authors: | Klein, M. | Deposit date: | 2015-12-09 | Release date: | 2016-05-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKC theta inhibitors. Bioorg.Med.Chem., 24, 2016
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5F20
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5F1Z
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