3FCT
 
 | | MATURE METAL CHELATASE CATALYTIC ANTIBODY WITH HAPTEN | | Descriptor: | CADMIUM ION, CALCIUM ION, MAGNESIUM ION, ... | | Authors: | Romesberg, F.E, Santarsiero, B.D, Barnes, D, Yin, J, Spiller, B, Schultz, P.G, Stevens, R.C. | | Deposit date: | 1999-06-13 | | Release date: | 1999-06-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and kinetic evidence for strain in biological catalysis.
Biochemistry, 37, 1998
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3D4S
 | | Cholesterol bound form of human beta2 adrenergic receptor. | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, Beta-2 adrenergic receptor/T4-lysozyme chimera, ... | | Authors: | Hanson, M.A, Cherezov, V, Roth, C.B, Griffith, M.T, Jaakola, V.-P, Chien, E.Y.T, Velasquez, J, Kuhn, P, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR) | | Deposit date: | 2008-05-14 | | Release date: | 2008-06-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor.
Structure, 16, 2008
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3E1U
 | | The Crystal Structure of the Anti-Viral APOBEC3G Catalytic Domain | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | Authors: | Holden, L, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S. | | Deposit date: | 2008-08-04 | | Release date: | 2008-10-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
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4JKV
 | | Structure of the human smoothened 7TM receptor in complex with an antitumor agent | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-fluoro-N-methyl-N-{1-[4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl]piperidin-4-yl}-2-(trifluoromethyl)benzamide, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Wang, C, Wu, H, Katritch, V, Han, G.W, Huang, X, Liu, W, Siu, F.Y, Roth, B.L, Cherezov, V, Stevens, R.C, GPCR Network (GPCR) | | Deposit date: | 2013-03-11 | | Release date: | 2013-04-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structure of the human smoothened receptor bound to an antitumour agent.
Nature, 497, 2013
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2N2F
 | | Solution NMR structure of Dynorphin 1-13 bound to Kappa Opioid Receptor | | Descriptor: | Dynorphin A(1-13) | | Authors: | O'Connor, C, White, K, Doncescu, N, Didenko, T, Roth, B.L, Czaplicki, G, Stevens, R.C, Wuthrich, K, Milon, A. | | Deposit date: | 2015-05-06 | | Release date: | 2015-09-09 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4L6R
 | | Structure of the class B human glucagon G protein coupled receptor | | Descriptor: | DI(HYDROXYETHYL)ETHER, Soluble cytochrome b562 and Glucagon receptor chimera | | Authors: | Siu, F.Y, He, M, de Graaf, C, Han, G.W, Yang, D, Zhang, Z, Zhou, C, Xu, Q, Wacker, D, Joseph, J.S, Liu, W, Lau, J, Cherezov, V, Katritch, V, Wang, M.W, Stevens, R.C, GPCR Network (GPCR) | | Deposit date: | 2013-06-12 | | Release date: | 2013-07-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure of the human glucagon class B G-protein-coupled receptor.
Nature, 499, 2013
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4J6S
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2OG3
 | | structure of the rna binding domain of n protein from SARS coronavirus in cubic crystal form | | Descriptor: | Nucleocapsid protein | | Authors: | Saikatendu, K, Joseph, J, Subramanian, V, Neuman, B, Buchmeier, M, Stevens, R.C, Kuhn, P. | | Deposit date: | 2007-01-05 | | Release date: | 2007-04-03 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Ribonucleocapsid formation of severe acute respiratory syndrome coronavirus through molecular action of the N-terminal domain of N protein.
J.Virol., 81, 2007
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4J5P
 | | Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase | | Descriptor: | (1S)-1-{5-[5-(bromomethyl)pyridin-2-yl]-1,3-oxazol-2-yl}-7-phenylheptan-1-ol, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Otrubova, K, Brown, M, McCormick, M.S, Han, G.W, O'Neal, S.T, Cravatt, B.F, Stevens, R.C, Lichtman, A.H, Boger, D.L. | | Deposit date: | 2013-02-08 | | Release date: | 2013-05-01 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Rational design of Fatty Acid amide hydrolase inhibitors that act by covalently bonding to two active site residues.
J.Am.Chem.Soc., 135, 2013
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2OZK
 | | Structure of an N-Terminal Truncated Form of Nendou (NSP15) From SARS-CORONAVIRUS | | Descriptor: | Uridylate-specific endoribonuclease | | Authors: | Saikatendu, K, Joseph, J, Subramanian, V, Neuman, B, Buchmeier, M, Stevens, R.C, Kuhn, P. | | Deposit date: | 2007-02-26 | | Release date: | 2007-05-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of a monomeric form of severe acute respiratory syndrome coronavirus endonuclease nsp15 suggests a role for hexamerization as an allosteric switch.
J.Virol., 81, 2007
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2OFZ
 | | Ultrahigh Resolution Crystal Structure of RNA Binding Domain of SARS Nucleopcapsid (N Protein) at 1.1 Angstrom Resolution in Monoclinic Form. | | Descriptor: | 1,2-ETHANEDIOL, Nucleocapsid protein | | Authors: | Saikatendu, K, Joseph, J, Subramanian, V, Neuman, B, Buchmeier, M, Stevens, R.C, Kuhn, P. | | Deposit date: | 2007-01-04 | | Release date: | 2007-04-03 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.17 Å) | | Cite: | Ribonucleocapsid formation of severe acute respiratory syndrome coronavirus through molecular action of the N-terminal domain of N protein.
J.Virol., 81, 2007
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4MBS
 | | Crystal Structure of the CCR5 Chemokine Receptor | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4,4-difluoro-N-[(1S)-3-{(3-exo)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl}-1-phenylpropyl]cyclohexanecarboxamide, Chimera protein of C-C chemokine receptor type 5 and Rubredoxin, ... | | Authors: | Tan, Q, Zhu, Y, Han, G.W, Li, J, Fenalti, G, Liu, H, Cherezov, V, Stevens, R.C, GPCR Network (GPCR), Zhao, Q, Wu, B. | | Deposit date: | 2013-08-19 | | Release date: | 2013-09-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex.
Science, 341, 2013
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2NP0
 | | Crystal structure of the Botulinum neurotoxin type B complexed with synaptotagamin-II ectodomain | | Descriptor: | Botulinum neurotoxin type B, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Chai, Q, Arndt, J.W, Stevens, R.C. | | Deposit date: | 2006-10-26 | | Release date: | 2006-12-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | Structural basis of cell surface receptor recognition by botulinum neurotoxin B.
Nature, 444, 2006
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1E74
 | | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R11E | | Descriptor: | ALPHA-CONOTOXIN IM1(R11E) | | Authors: | Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C. | | Deposit date: | 2000-08-24 | | Release date: | 2000-12-27 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
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1E75
 | | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R7L | | Descriptor: | ALPHA-CONOTOXIN IM1(R7L) | | Authors: | Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C. | | Deposit date: | 2000-08-24 | | Release date: | 2000-12-27 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
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1E76
 | | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT D5N | | Descriptor: | ALPHA-CONOTOXIN IM1(D5N) | | Authors: | Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C. | | Deposit date: | 2000-08-24 | | Release date: | 2000-12-27 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
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1IM1
 | | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1, 20 STRUCTURES | | Descriptor: | ALPHA-CONOTOXIN IM1 | | Authors: | Rogers, J.P, Luginbuhl, P, Shen, G.S, Mccabe, R.T, Stevens, R.C, Wemmer, D.E. | | Deposit date: | 1998-11-18 | | Release date: | 1999-06-15 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of alpha-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors.
Biochemistry, 38, 1999
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1KEM
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1LTU
 | | CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM, APO (NO IRON BOUND) STRUCTURE | | Descriptor: | PHENYLALANINE-4-HYDROXYLASE | | Authors: | Erlandsen, H, Kim, J.Y, Patch, M.G, Han, A, Volner, A, Abu-Omar, M.M, Stevens, R.C. | | Deposit date: | 2002-05-20 | | Release date: | 2002-07-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
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1LTZ
 | | CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE HAS BOUND IRON (III) AND OXIDIZED COFACTOR 7,8-DIHYDROBIOPTERIN | | Descriptor: | 7,8-DIHYDROBIOPTERIN, CHLORIDE ION, FE (III) ION, ... | | Authors: | Erlandsen, H, Kim, J.Y, Patch, M.G, Han, A, Volner, A, Abu-Omar, M.M, Stevens, R.C. | | Deposit date: | 2002-05-21 | | Release date: | 2002-07-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
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1KEL
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1LTV
 | | CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE WITH BOUND OXIDIZED Fe(III) | | Descriptor: | FE (III) ION, PHENYLALANINE-4-HYDROXYLASE | | Authors: | Erlandsen, H, Kim, J.Y, Patch, M.G, Han, A, Volner, A, Abu-Omar, M.M, Stevens, R.C. | | Deposit date: | 2002-05-20 | | Release date: | 2002-07-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
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2IDY
 | | NMR Structure of the SARS-CoV non-structural protein nsp3a | | Descriptor: | NSP3 | | Authors: | Serrano, P, Almeida, M.S, Johnson, M.A, Horst, R, Herrmann, T, Joseph, J, Saikatendu, K, Subramanian, V, Stevens, R.C, Kuhn, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | | Deposit date: | 2006-09-15 | | Release date: | 2006-12-05 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus.
J.Virol., 81, 2007
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2GRI
 | | NMR Structure of the SARS-CoV non-structural protein nsp3a | | Descriptor: | NSP3 | | Authors: | Serrano, P, Almeida, M.S, Johnson, M.A, Herrmann, T, Saikatendu, K.S, Joseph, J, Subramanian, V, Neuman, B.W, Buchmeier, M.J, Stevens, R.C, Kuhn, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | | Deposit date: | 2006-04-24 | | Release date: | 2006-12-19 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus.
J.Virol., 81, 2007
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1DMW
 | | CRYSTAL STRUCTURE OF DOUBLE TRUNCATED HUMAN PHENYLALANINE HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN | | Descriptor: | 7,8-DIHYDROBIOPTERIN, FE (III) ION, PHENYLALANINE HYDROXYLASE | | Authors: | Erlandsen, H, Stevens, R.C, Flatmark, T. | | Deposit date: | 1999-12-15 | | Release date: | 2000-03-24 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase.
Biochemistry, 39, 2000
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