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7Z63
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BU of 7z63 by Molmil
Structure of the LecA lectin from Pseudomonas aeruginosa in complex with a biaryl-thiogalactoside
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, PA-I galactophilic lectin, ...
Authors:Varrot, A.
Deposit date:2022-03-10
Release date:2023-01-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Discovery of potent 1,1-diarylthiogalactoside glycomimetic inhibitors of Pseudomonas aeruginosa LecA with antibiofilm properties.
Eur.J.Med.Chem., 247, 2022
1QKJ
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BU of 1qkj by Molmil
T4 Phage B-Glucosyltransferase, Substrate Binding and Proposed Catalytic Mechanism
Descriptor: BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE
Authors:Morera, S, Imberty, I, Aschke-Sonnenborn, U, Ruger, W, Freemont, P.S.
Deposit date:1999-07-22
Release date:1999-07-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:T4 Phage Beta-Glucosyltransferase: Substrate Binding and Proposed Catalytic Mechanism
J.Mol.Biol., 292, 1999
6HTN
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BU of 6htn by Molmil
Structure of a fucose lectin from Kordia zhangzhouensis in complex with methyl-fucoside
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ...
Authors:Varrot, A.
Deposit date:2018-10-04
Release date:2019-01-23
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Architecture and Evolution of Blade Assembly in beta-propeller Lectins.
Structure, 27, 2019
7QE3
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BU of 7qe3 by Molmil
Se-M variant of B-trefoil lectin from Salpingoeca rosetta in complex with GalNAc
Descriptor: (2S)-hexane-1,2,6-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-galactopyranose, ...
Authors:Notova, S, Varrot, A.
Deposit date:2021-12-01
Release date:2022-09-14
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3.
Commun Biol, 5, 2022
7QE4
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BU of 7qe4 by Molmil
B-trefoil lectin from Salpingoeca rosetta in complex with GalNAc
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-galactopyranose, CHLORIDE ION, ...
Authors:Notova, S, Varrot, A.
Deposit date:2021-12-01
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3.
Commun Biol, 5, 2022
7R55
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BU of 7r55 by Molmil
B-trefoil lectin from Salpingoeca rosetta in complex with Gb3
Descriptor: 1,2-ETHANEDIOL, Sarol-1, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
Authors:Notova, S, Varrot, A.
Deposit date:2022-02-10
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3.
Commun Biol, 5, 2022
7OLW
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BU of 7olw by Molmil
Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-N-fucoside ligand
Descriptor: 5-(3-aminophenyl)furan-2-carboxamido-(beta-L-fucopyranose), Lectin
Authors:Bermeo, R, Varrot, A.
Deposit date:2021-05-20
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia 's BC2L-C Lectin.
Acs Chem.Biol., 17, 2022
7OLU
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BU of 7olu by Molmil
Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-C-fucoside ligand
Descriptor: (2-(4-(beta-L-fucopyranosylethynyl)phenyl)-2-methylpropan-1-amine, Lectin
Authors:Bermeo, R, Varrot, A.
Deposit date:2021-05-20
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia 's BC2L-C Lectin.
Acs Chem.Biol., 17, 2022
1BJQ
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BU of 1bjq by Molmil
THE DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH ADENINE
Descriptor: ADENINE, CALCIUM ION, LECTIN, ...
Authors:Hamelryck, T.W, Loris, R, Bouckaert, J, Dao-Thi, M.H, Wyns, L, Etzler, M.
Deposit date:1998-06-26
Release date:1998-12-30
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus.
J.Mol.Biol., 286, 1999
1S1A
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BU of 1s1a by Molmil
Pterocarpus angolensis seed lectin (PAL) with one binding site free and one binding site containing the disaccharide Man(a1-3)ManMe
Descriptor: CALCIUM ION, Lectin, MANGANESE (II) ION, ...
Authors:Buts, L, Imberty, A, Wyns, L, Beeckmans, S, Loris, R.
Deposit date:2004-01-06
Release date:2005-01-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:

5O7W
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BU of 5o7w by Molmil
Crystal structure of the 4-FLUORO RSL lectin in complex with Lewis x tetrasaccharide
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Putative fucose-binding lectin protein, ...
Authors:Varrot, A.
Deposit date:2017-06-09
Release date:2018-06-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs.
ACS Chem. Biol., 13, 2018
5O7U
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BU of 5o7u by Molmil
Crystal structure of the 7-Fluorotryptophan RSL lectin in complex with Lewis x tetrasaccharide
Descriptor: CALCIUM ION, MAGNESIUM ION, Putative fucose-binding lectin protein, ...
Authors:Varrot, A.
Deposit date:2017-06-09
Release date:2018-06-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs.
ACS Chem. Biol., 13, 2018
5O7V
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BU of 5o7v by Molmil
Crystal structure of the 5F-tryptophan RSL lectin in complex with Lewis x tetrasaccharide
Descriptor: CHLORIDE ION, ETHANOL, Fucose-binding lectin protein, ...
Authors:Varrot, A.
Deposit date:2017-06-09
Release date:2018-06-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs.
ACS Chem. Biol., 13, 2018
5MB4
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BU of 5mb4 by Molmil
Crystal Structure of the Psathyrella asperospora lectin PAL in complex with GlcNAc
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, GlcNAc specific lectin, ...
Authors:Ribeiro, J, Varrot, A.
Deposit date:2016-11-07
Release date:2017-02-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biophysical characterization and structural determination of the potent cytotoxic Psathyrella asperospora lectin.
Proteins, 85, 2017
5D21
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BU of 5d21 by Molmil
Multivalency Effects in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting Lectin LecA
Descriptor: CALCIUM ION, LecA, phenyl beta-D-galactopyranoside
Authors:Bergmann, M, Michaud, G, Visini, R, Jin, X, Stocker, A, Darbre, T, Reymond, J.-L.
Deposit date:2015-08-05
Release date:2015-11-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multivalency effects on Pseudomonas aeruginosa biofilm inhibition and dispersal by glycopeptide dendrimers targeting lectin LecA.
Org.Biomol.Chem., 14, 2016
5D2A
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BU of 5d2a by Molmil
Bifunctional dendrimers
Descriptor: 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, Fucose-binding lectin, ...
Authors:Michaud, G, Visini, R, Stocker, A, Darbre, T, Reymond, J.L.
Deposit date:2015-08-05
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.134 Å)
Cite:Overcoming antibiotic resistance inPseudomonas aeruginosabiofilms using glycopeptide dendrimers.
Chem Sci, 7, 2016
1G7Y
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BU of 1g7y by Molmil
THE CRYSTAL STRUCTURE OF THE 58KD VEGETATIVE LECTIN FROM THE TROPICAL LEGUME DOLICHOS BIFLORUS
Descriptor: CALCIUM ION, MANGANESE (II) ION, STEM/LEAF LECTIN DB58, ...
Authors:Buts, L, Hamelryck, T.W, Loris, R, Dao-Thi, M.-H, Wyns, L, Etzler, M.E.
Deposit date:2000-11-15
Release date:2000-11-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Weak protein-protein interactions in lectins: the crystal structure of a vegetative lectin from the legume Dolichos biflorus.
J.Mol.Biol., 309, 2001
1LEM
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BU of 1lem by Molmil
THE MONOSACCHARIDE BINDING SITE OF LENTIL LECTIN: AN X-RAY AND MOLECULAR MODELLING STUDY
Descriptor: CALCIUM ION, LECTIN, MANGANESE (II) ION, ...
Authors:Loris, R, Wyns, L.
Deposit date:1993-11-17
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:The monosaccharide binding site of lentil lectin: an X-ray and molecular modelling study.
Glycoconj.J., 11, 1994
1LES
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BU of 1les by Molmil
LENTIL LECTIN COMPLEXED WITH SUCROSE
Descriptor: CALCIUM ION, LENTIL LECTIN, MANGANESE (II) ION, ...
Authors:Hamelryck, T, Loris, R.
Deposit date:1995-08-23
Release date:1995-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:NMR, molecular modeling, and crystallographic studies of lentil lectin-sucrose interaction.
J.Biol.Chem., 270, 1995
1LUL
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BU of 1lul by Molmil
DB58, A LEGUME LECTIN FROM DOLICHOS BIFLORUS
Descriptor: CALCIUM ION, LECTIN DB58, MANGANESE (II) ION
Authors:Hamelryck, T.W, Bouckaert, J, Dao-Thi, M.H, Wyns, L, Etzler, M, Loris, R.
Deposit date:1998-06-30
Release date:1998-12-30
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus.
J.Mol.Biol., 286, 1999
1PLG
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BU of 1plg by Molmil
EVIDENCE FOR THE EXTENDED HELICAL NATURE OF POLYSACCHARIDE EPITOPES. THE 2.8 ANGSTROMS RESOLUTION STRUCTURE AND THERMODYNAMICS OF LIGAND BINDING OF AN ANTIGEN BINDING FRAGMENT SPECIFIC FOR ALPHA-(2->8)-POLYSIALIC ACID
Descriptor: IGG2A=KAPPA=
Authors:Evans, S.V, Sigurskjold, B.W, Jennings, H.J, Brisson, J.-R, Tse, W.C, To, R, Altman, E, Frosch, M, Weisgerber, C, Kratzin, H, Klebert, S, Vaesen, M, Bitter-Suermann, D, Rose, D.R, Young, N.M, Bundle, D.R.
Deposit date:1995-04-24
Release date:1996-04-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Evidence for the extended helical nature of polysaccharide epitopes. The 2.8 A resolution structure and thermodynamics of ligand binding of an antigen binding fragment specific for alpha-(2-->8)-polysialic acid.
Biochemistry, 34, 1995
3ZFJ
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BU of 3zfj by Molmil
N-terminal domain of pneumococcal PhtD protein with bound Zn(II)
Descriptor: PNEUMOCOCCAL HISTIDINE TRIAD PROTEIN D, ZINC ION
Authors:Bersch, B, Bougault, C, Favier, A, Gabel, F, Roux, L, Vernet, T, Durmort, C.
Deposit date:2012-12-11
Release date:2013-11-20
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:New Insights Into Histidine Triad Proteins: Solution Structure of a Streptococcus Pneumoniae Phtd Domain and Zinc Transfer to Adcaii.
Plos One, 8, 2013
1JIV
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BU of 1jiv by Molmil
T4 phage BGT in complex with Mg2+ : Form II
Descriptor: DNA BETA-GLUCOSYLTRANSFERASE, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE
Authors:Morera, S, Lariviere, L, Kurzeck, J, Aschke-Sonnenborn, U, Freemont, P.S, Janin, J, Ruger, W.
Deposit date:2001-07-03
Release date:2001-08-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding.
J.Mol.Biol., 311, 2001
1JIU
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BU of 1jiu by Molmil
T4 Phage BGT in Complex with Mg2+ : Form I
Descriptor: DNA BETA-GLUCOSYLTRANSFERASE, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE
Authors:Morera, S, Lariviere, L, Kurzeck, J, Aschke-Sonnenborn, U, Freemont, P.S, Janin, J, Ruger, W.
Deposit date:2001-07-03
Release date:2001-08-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding.
J.Mol.Biol., 311, 2001
1JIX
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BU of 1jix by Molmil
T4 Phage BGT in Complex with Ca2+
Descriptor: CALCIUM ION, DNA BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE
Authors:Morera, S, Lariviere, L, Kurzeck, J, Aschke-Sonnenborn, U, Freemont, P.S, Janin, J, Ruger, W.
Deposit date:2001-07-03
Release date:2001-08-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding.
J.Mol.Biol., 311, 2001

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數據於2024-10-16公開中

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