5O7W

Crystal structure of the 4-FLUORO RSL lectin in complex with Lewis x tetrasaccharide

Summary for 5O7W

Entry DOI	10.2210/pdb5o7w/pdb
Descriptor	Putative fucose-binding lectin protein, alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-galactopyranose, ... (7 entities in total)
Functional Keywords	lectin, fluorinated tryptophan, lewis x, carbohydrate, sugar binding protein
Biological source	Ralstonia solanacearum
Total number of polymer chains	2
Total formula weight	21571.75
Authors	Varrot, A. (deposition date: 2017-06-09, release date: 2018-06-06, Last modification date: 2024-01-17)
Primary citation	Tobola, F.,Lelimousin, M.,Varrot, A.,Gillon, E.,Darnhofer, B.,Blixt, O.,Birner-Gruenberger, R.,Imberty, A.,Wiltschi, B. Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs. ACS Chem. Biol., 13:2211-2219, 2018 Cited by PubMed: 29812892 DOI: 10.1021/acschembio.8b00377 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation