8OXK
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8OXL
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8PHY
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8P3Q
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![BU of 8p3q by Molmil](/molmil-images/mine/8p3q) | Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 3 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor 2, ... | Authors: | Zhang, D, Krieger, J.M, Yamashita, K, Greger, I. | Deposit date: | 2023-05-18 | Release date: | 2023-08-30 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621, 2023
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8P3Z
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![BU of 8p3z by Molmil](/molmil-images/mine/8p3z) | Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 2 | Descriptor: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | Authors: | Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H. | Deposit date: | 2023-05-18 | Release date: | 2023-08-30 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621, 2023
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8P3Y
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![BU of 8p3y by Molmil](/molmil-images/mine/8p3y) | Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 3 | Descriptor: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | Authors: | Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H. | Deposit date: | 2023-05-18 | Release date: | 2023-08-30 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621, 2023
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8PYI
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![BU of 8pyi by Molmil](/molmil-images/mine/8pyi) | Human IGF1R with inhibitor 6 | Descriptor: | 3-[8-azanyl-1-(4-ethoxy-8-fluoranyl-2-phenyl-quinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutan-1-ol, Insulin-like growth factor 1 receptor beta chain | Authors: | Dreyer, M.K, Wang, J, Elkins, J.M. | Deposit date: | 2023-07-25 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Human IGF1R with inhibitor 6 To Be Published
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8PYJ
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![BU of 8pyj by Molmil](/molmil-images/mine/8pyj) | Human IGF1R with inhibitor 8 | Descriptor: | 5,5-dimethyl-1-(quinolin-4-ylmethyl)-3-[4-(trifluoromethylsulfonyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | Authors: | Dreyer, M.K, Wang, J, Elkins, J.M. | Deposit date: | 2023-07-25 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | Human IGF1R with inhibitor 8 To Be Published
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8PYK
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![BU of 8pyk by Molmil](/molmil-images/mine/8pyk) | Human IGF1R with inhibitor 47 | Descriptor: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, Insulin-like growth factor 1 receptor beta chain, NICKEL (II) ION | Authors: | Dreyer, M.K, Wang, J, Elkins, J.M. | Deposit date: | 2023-07-25 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Human IGF1R with inhibitor 47 To Be Published
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8PYL
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![BU of 8pyl by Molmil](/molmil-images/mine/8pyl) | Human IGF1R with inhibitor 53 | Descriptor: | (5S)-5-methyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | Authors: | Dreyer, M.K, Wang, J, Elkins, J.M. | Deposit date: | 2023-07-25 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Human IGF1R with inhibitor 53 To Be Published
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8PYM
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![BU of 8pym by Molmil](/molmil-images/mine/8pym) | Human IGF1R with inhibitor 54 | Descriptor: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | Authors: | Dreyer, M.K, Wang, J, Elkins, J.M. | Deposit date: | 2023-07-25 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.652 Å) | Cite: | Human IGF1R with inhibitor 54 To Be Published
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8PYN
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![BU of 8pyn by Molmil](/molmil-images/mine/8pyn) | Human IGF1R with inhibitor 56 | Descriptor: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfonyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | Authors: | Dreyer, M.K, Wang, J, Elkins, J.M. | Deposit date: | 2023-07-25 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Human IGF1R with inhibitor 56 To Be Published
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8P3S
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![BU of 8p3s by Molmil](/molmil-images/mine/8p3s) | Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 2 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor 2, ... | Authors: | Zhang, D, Krieger, J.M, Yamashita, K, Greger, I. | Deposit date: | 2023-05-18 | Release date: | 2023-08-30 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621, 2023
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8PX5
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![BU of 8px5 by Molmil](/molmil-images/mine/8px5) | Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe., solved at wavelength 2.75 A | Descriptor: | Rpb7-binding protein seb1 | Authors: | El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Wittmann, S, Renner, M, Grimes, J.M, Wagner, A. | Deposit date: | 2023-07-22 | Release date: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Experimental phasing opportunities for macromolecular crystallography at very long wavelengths. Commun Chem, 6, 2023
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1IAM
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![BU of 1iam by Molmil](/molmil-images/mine/1iam) | STRUCTURE OF THE TWO AMINO-TERMINAL DOMAINS OF HUMAN INTERCELLULAR ADHESION MOLECULE-1, ICAM-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERCELLULAR ADHESION MOLECULE-1 | Authors: | Bella, J, Kolatkar, P.R, Marlor, C, Greve, J.M, Rossmann, M.G. | Deposit date: | 1998-02-22 | Release date: | 1998-04-29 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of the two amino-terminal domains of human ICAM-1 suggests how it functions as a rhinovirus receptor and as an LFA-1 integrin ligand. Proc.Natl.Acad.Sci.USA, 95, 1998
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8P4K
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![BU of 8p4k by Molmil](/molmil-images/mine/8p4k) | Vaccinia Virus palisade layer A10 trimer | Descriptor: | Core protein OPG136 | Authors: | Datler, J, Hansen, J.M, Thader, A, Schloegl, A, Hodirnau, V.V, Schur, F.K.M. | Deposit date: | 2023-05-22 | Release date: | 2024-01-17 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores. Nat.Struct.Mol.Biol., 2024
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1LAX
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![BU of 1lax by Molmil](/molmil-images/mine/1lax) | CRYSTAL STRUCTURE OF MALE31, A DEFECTIVE FOLDING MUTANT OF MALTOSE-BINDING PROTEIN | Descriptor: | MALTOSE-BINDING PROTEIN MUTANT MALE31, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Saul, F.A, Mourez, M, Vulliez-le Normand, B, Sassoon, N, Bentley, G.A, Betton, J.M. | Deposit date: | 2002-03-29 | Release date: | 2003-03-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of a defective folding protein PROTEIN SCI., 12, 2003
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8PWH
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![BU of 8pwh by Molmil](/molmil-images/mine/8pwh) | Atomic structure and conformational variability of the HER2-Trastuzumab-Pertuzumab complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, Pertuzumab Fab light chain, ... | Authors: | Ruedas, R, Vuillemot, R, Tubiana, T, Winter, J.M, Pieri, L, Arteni, A.A, Samson, C, Jonic, J, Mathieu, M, Bressanelli, S. | Deposit date: | 2023-07-20 | Release date: | 2024-02-21 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex. J.Struct.Biol., 216, 2024
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8R2G
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![BU of 8r2g by Molmil](/molmil-images/mine/8r2g) | Crystal structure of a BRCA2-DMC1 complex | Descriptor: | Breast cancer type 2 susceptibility protein, Meiotic recombination protein DMC1/LIM15 homolog | Authors: | Dunce, J.M, Davies, O.R. | Deposit date: | 2023-11-05 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Crystal structure of a BRCA2-DMC1 complex To Be Published
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8Q6K
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![BU of 8q6k by Molmil](/molmil-images/mine/8q6k) | Human IgD Fab in complex with an orthosteric inhibitor of Phl p 7 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Human IgD Fab heavy chain, ... | Authors: | Davies, A.M, Vester, S.K, McDonnell, J.M. | Deposit date: | 2023-08-11 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Expanding the Anti-Phl p 7 Antibody Toolkit: An Anti-Idiotype Nanobody Inhibitor. Antibodies, 12, 2023
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8QOE
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![BU of 8qoe by Molmil](/molmil-images/mine/8qoe) | Inward-facing conformation of the ABC transporter BmrA | Descriptor: | Multidrug resistance ABC transporter ATP-binding/permease protein BmrA | Authors: | Di Cesare, M, Kaplan, E, Valimehr, S, Hanssen, E, Orelle, C, Jault, J.M. | Deposit date: | 2023-09-28 | Release date: | 2023-12-20 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains. J.Biol.Chem., 300, 2023
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8P1K
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8P1M
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8Q6J
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![BU of 8q6j by Molmil](/molmil-images/mine/8q6j) | Atomic structure and conformational variability of the HER2-Trastuzumab-Pertuzumab complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, Pertuzumab Fab light chain, ... | Authors: | Ruedas, R, Vuillemot, R, Tubiana, T, Winter, J.M, Pieri, L, Arteni, A.A, Samson, C, Jonic, J, Mathieu, M, Bressanelli, S. | Deposit date: | 2023-08-11 | Release date: | 2023-09-20 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex. J.Struct.Biol., 216, 2024
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8RJL
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![BU of 8rjl by Molmil](/molmil-images/mine/8rjl) | Structure of a first order Sierpinski triangle formed by the H369R mutant of the citrate synthase from Synechococcus elongatus | Descriptor: | Citrate synthase | Authors: | Lo, Y.K, Bohn, S, Sendker, F.L, Schuller, J.M, Hochberg, G. | Deposit date: | 2023-12-21 | Release date: | 2024-02-28 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Emergence of fractal geometries in the evolution of a metabolic enzyme. Nature, 628, 2024
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