1R8C
| Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide | Descriptor: | MANGANESE (II) ION, SODIUM ION, URIDINE 5'-TRIPHOSPHATE, ... | Authors: | Xiong, Y, Li, F, Wang, J, Weiner, A.M, Steitz, T.A. | Deposit date: | 2003-10-23 | Release date: | 2003-12-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes Mol.Cell, 12, 2003
|
|
1R8A
| Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide Complexes | Descriptor: | MANGANESE (II) ION, SODIUM ION, tRNA nucleotidyltransferase | Authors: | Xiong, Y, Li, F, Wang, J, Weiner, A.M, Steitz, T.A. | Deposit date: | 2003-10-23 | Release date: | 2003-12-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes Mol.Cell, 12, 2003
|
|
1R8B
| Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Xiong, Y, Li, F, Wang, J, Weiner, A.M, Steitz, T.A. | Deposit date: | 2003-10-23 | Release date: | 2003-12-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes Mol.Cell, 12, 2003
|
|
8E7Y
| RsTSPO A138F with two heme bound | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan-rich sensory protein | Authors: | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | Deposit date: | 2022-08-25 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry, 62, 2023
|
|
8E7Z
| RsTSPO mutant -A138F | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Tryptophan-rich sensory protein | Authors: | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | Deposit date: | 2022-08-25 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry, 62, 2023
|
|
8E7W
| RsTSPO A139T with Heme | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | Deposit date: | 2022-08-25 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry, 62, 2023
|
|
8E7X
| RsTSPO A138F with one Heme bound | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan-rich sensory protein | Authors: | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | Deposit date: | 2022-08-25 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry, 62, 2023
|
|
4QL1
| Crystal structure of human WDR5 in complex with compound OICR-9429 | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide, ... | Authors: | Dong, A, Dombrovski, L, Walker, J.R, Getlik, M, Kuznetsova, E, Smil, D, Barsyte, D, Li, F, Poda, G, Senisterra, G, Marcellus, R, Al-Awar, R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2014-06-10 | Release date: | 2014-12-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Pharmacological targeting of the Wdr5-MLL interaction in C/EBP alpha N-terminal leukemia. Nat.Chem.Biol., 11, 2015
|
|
3CZ3
| Crystal structure of Tomato Aspermy Virus 2b in complex with siRNA | Descriptor: | Protein 2b, RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*A)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*G)-3') | Authors: | Ma, J.B, Li, F, Ding, S.W, Patel, D.J. | Deposit date: | 2008-04-27 | Release date: | 2009-05-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Structural Basis for siRNA Recognition by 2b, a Viral Suppressor of Non-Cell Autonomous RNA Silencing To be Published
|
|
7KM5
| Crystal structure of SARS-CoV-2 RBD complexed with Nanosota-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Spike protein S1, ... | Authors: | Ye, G, Shi, K, Aihara, H, Li, F. | Deposit date: | 2020-11-02 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | The development of Nanosota - 1 as anti-SARS-CoV-2 nanobody drug candidates. Elife, 10, 2021
|
|
8J3Y
| |
8J3X
| |
4YRB
| mouse TDH mutant R180K with NAD+ bound | Descriptor: | L-threonine 3-dehydrogenase, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | He, C, Li, F. | Deposit date: | 2015-03-14 | Release date: | 2016-02-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis J.Struct.Biol., 192, 2015
|
|
4YRA
| mouse TDH in the apo form | Descriptor: | L-threonine 3-dehydrogenase, mitochondrial | Authors: | He, C, Li, F. | Deposit date: | 2015-03-14 | Release date: | 2016-02-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis J.Struct.Biol., 192, 2015
|
|
4YND
| The Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2 | Descriptor: | N-cyclohexyl-N~3~-[2-(3,4-dichlorophenyl)ethyl]-N-(2-{[(2R)-2-hydroxy-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-8-yl)ethyl]amino}ethyl)-beta-alaninamide, N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ... | Authors: | Sweis, R.F, Wang, Z, Algire, M, Arrowsmith, C.H, Brown, P.J, Chiang, G.C, Guo, J, Jakob, C.G, Kennedy, S, Li, F, Soni, N.B, Vedadi, M, Pappano, W.N. | Deposit date: | 2015-03-09 | Release date: | 2015-05-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2. Acs Med.Chem.Lett., 6, 2015
|
|
4YR9
| mouse TDH with NAD+ bound | Descriptor: | GLYCEROL, L-threonine 3-dehydrogenase, mitochondrial, ... | Authors: | He, C, Li, F. | Deposit date: | 2015-03-14 | Release date: | 2016-02-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis J.Struct.Biol., 192, 2015
|
|
8GY6
| |
5CQR
| Dimerization of Elp1 is essential for Elongator complex assembly | Descriptor: | Elongator complex protein 1 | Authors: | Lin, Z, Xu, H, Li, F, Diao, W, Long, J, Shen, Y. | Deposit date: | 2015-07-22 | Release date: | 2015-08-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.015 Å) | Cite: | Dimerization of elongator protein 1 is essential for Elongator complex assembly. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
5CQS
| Dimerization of Elp1 is essential for Elongator complex assembly | Descriptor: | Elongator complex protein 1 | Authors: | Lin, Z, Xu, H, Li, F, Diao, W, Long, J, Shen, Y. | Deposit date: | 2015-07-22 | Release date: | 2015-08-19 | Last modified: | 2020-02-19 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Dimerization of elongator protein 1 is essential for Elongator complex assembly. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
3R4D
| Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CEA-related cell adhesion molecule 1, ... | Authors: | Peng, G.Q, Sun, D.W, Rajashankar, K.R, Qian, Z.H, Holmes, K.V, Li, F. | Deposit date: | 2011-03-17 | Release date: | 2011-06-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3SCI
| Crystal structure of spike protein receptor-binding domain from a predicted SARS coronavirus human strain complexed with human receptor ACE2 | Descriptor: | Angiotensin-converting enzyme 2, CHLORIDE ION, Spike glycoprotein, ... | Authors: | Wu, K, Peng, G, Wilken, M, Geraghty, R, Li, F. | Deposit date: | 2011-06-07 | Release date: | 2012-02-08 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus. J.Biol.Chem., 287, 2012
|
|
3SCK
| Crystal structure of spike protein receptor-binding domain from a predicted SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2 | Descriptor: | Angiotensin-converting enzyme 2 chimera, CHLORIDE ION, Spike glycoprotein, ... | Authors: | Wu, K, Peng, G, Wilken, M, Geraghty, R, Li, F. | Deposit date: | 2011-06-07 | Release date: | 2012-02-08 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus. J.Biol.Chem., 287, 2012
|
|
3SCL
| Crystal structure of spike protein receptor-binding domain from SARS coronavirus epidemic strain complexed with human-civet chimeric receptor ACE2 | Descriptor: | Angiotensin-converting enzyme 2 chimera, CHLORIDE ION, Spike glycoprotein, ... | Authors: | Wu, K, Peng, G, Wilken, M, Geraghty, R, Li, F. | Deposit date: | 2011-06-07 | Release date: | 2012-02-08 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus. J.Biol.Chem., 287, 2012
|
|
3SCJ
| Crystal structure of spike protein receptor-binding domain from a predicted SARS coronavirus civet strain complexed with human receptor ACE2 | Descriptor: | Angiotensin-converting enzyme 2, CHLORIDE ION, Spike glycoprotein, ... | Authors: | Wu, K, Peng, G, Wilken, M, Geraghty, R, Li, F. | Deposit date: | 2011-06-07 | Release date: | 2012-02-08 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus. J.Biol.Chem., 287, 2012
|
|
2G92
| |