7KEX
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7KF9
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5FBH
| Crystal structure of the extracellular domain of human calcium sensing receptor with bound Gd3+ | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ... | Authors: | Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J. | Deposit date: | 2015-12-14 | Release date: | 2016-06-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist. Sci Adv, 2, 2016
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7M3N
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7M3M
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7M3L
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7M3O
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7M8L
| EBOV GP bound to rEBOV-442 and rEBOV-515 Fabs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Virion spike glycoprotein 1, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2021-03-30 | Release date: | 2021-11-10 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Pan-ebolavirus protective therapy by two multifunctional human antibodies. Cell, 184, 2021
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7KEJ
| BDBV-289 bound to EBOV GPdMuc Makona | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain (HC) BDBV-289, Antibody Fab light chain (LC) BDBV-289, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2020-10-11 | Release date: | 2021-06-23 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
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5FBK
| Crystal structure of the extracellular domain of human calcium sensing receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ... | Authors: | Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J. | Deposit date: | 2015-12-14 | Release date: | 2016-06-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist. Sci Adv, 2, 2016
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7N6P
| Crystal structure of the anti-EBOV and SUDV monoclonal antibody 1C3 Fab | Descriptor: | 1C3 Fab heavy chain, 1C3 Fab light chain | Authors: | Milligan, J.C, Yu, X, Buck, T, Saphire, E.O. | Deposit date: | 2021-06-08 | Release date: | 2022-04-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses. Cell, 185, 2022
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6JQ5
| The structure of Hatchet Ribozyme | Descriptor: | MAGNESIUM ION, RNA (82-MER) | Authors: | Ren, A, Zheng, L. | Deposit date: | 2019-03-29 | Release date: | 2019-06-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.059 Å) | Cite: | Hatchet ribozyme structure and implications for cleavage mechanism. Proc.Natl.Acad.Sci.USA, 116, 2019
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7SWD
| Structure of EBOV GP lacking the mucin-like domain with 1C11 scFv and 1C3 Fab bound | Descriptor: | 1C11 scFv, 1C3 heavy chain, 1C3 light chain, ... | Authors: | Milligan, J.C, Yu, X, Saphire, E.O. | Deposit date: | 2021-11-19 | Release date: | 2022-04-06 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses. Cell, 185, 2022
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1ZXF
| Solution structure of a self-sacrificing resistance protein, CalC from Micromonospora echinospora | Descriptor: | CalC | Authors: | Singh, S, Hager, M.H, Zhang, C, Griffith, B.R, Lee, M.S, Hallenga, K, Markley, J.L, Thorson, J.S, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2005-06-08 | Release date: | 2005-12-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural insight into the self-sacrifice mechanism of enediyne resistance. Acs Chem.Biol., 1, 2006
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6N7J
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6N7U
| apo-BDBV223 Fab | Descriptor: | BDBV223 antibody heavy chain, BDBV223 antibody light chain | Authors: | King, L.B, West, B.R, Saphire, E.O. | Deposit date: | 2018-11-28 | Release date: | 2019-03-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk. Nat Commun, 10, 2019
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2R82
| Pyruvate phosphate dikinase (PPDK) triple mutant R219E/E271R/S262D adapts a second conformational state | Descriptor: | Pyruvate, phosphate dikinase, SULFATE ION | Authors: | Lim, K, Read, R.J, Chen, C.C, Herzberg, O. | Deposit date: | 2007-09-10 | Release date: | 2008-01-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Swiveling domain mechanism in pyruvate phosphate dikinase. Biochemistry, 46, 2007
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6VJQ
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8HYJ
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7DJT
| Human SARM1 inhibitory state bounded with inhibitor dHNN | Descriptor: | NAD(+) hydrolase SARM1, O3-methyl O5-(2-methylpropyl) 2,6-dimethyl-4-[2-(oxidanylamino)phenyl]pyridine-3,5-dicarboxylate | Authors: | Cai, Y, Zhang, H. | Deposit date: | 2020-11-21 | Release date: | 2021-05-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate. Elife, 10, 2021
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7JSO
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1KBL
| PYRUVATE PHOSPHATE DIKINASE | Descriptor: | AMMONIUM ION, PYRUVATE PHOSPHATE DIKINASE, SULFATE ION | Authors: | Herzberg, O, Chen, C.C, Liu, S. | Deposit date: | 2001-11-06 | Release date: | 2002-01-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Pyruvate site of pyruvate phosphate dikinase: crystal structure of the enzyme-phosphonopyruvate complex, and mutant analysis Biochemistry, 41, 2002
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1KC7
| Pyruvate Phosphate Dikinase with Bound Mg-phosphonopyruvate | Descriptor: | MAGNESIUM ION, PHOSPHONOPYRUVATE, SULFATE ION, ... | Authors: | Chen, C.C, Howard, A, Herzberg, O. | Deposit date: | 2001-11-07 | Release date: | 2002-01-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Pyruvate site of pyruvate phosphate dikinase: crystal structure of the enzyme-phosphonopyruvate complex, and mutant analysis Biochemistry, 41, 2002
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2LWZ
| NMR Structures of Single-chain Insulin | Descriptor: | SINGLE-CHAIN INSULIN | Authors: | Weiss, M.A, Yang, Y. | Deposit date: | 2012-08-09 | Release date: | 2013-08-28 | Method: | SOLUTION NMR | Cite: | Dynamic repair of an amyloidogenic protein: Insulin fibrillation is blocked by tethering a nascent alpha-helix To be Published
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6VHJ
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