Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8DJD
DownloadVisualize
BU of 8djd by Molmil
CRYSTAL STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3 BETA COMPLEXED WITH 3-[(CYCLOPROPYLMETHYL)AMINO] -N-(4-PHENYLPYRIDIN-3-YL)IMIDAZO[1,2-B]PYRIDAZINE-8-CARBOX AMIDE
Descriptor: 2-[(cyclopropanecarbonyl)amino]-N-(5-phenylpyridin-3-yl)pyridine-4-carboxamide, Glycogen synthase kinase-3 beta
Authors:Lewis, H.A, Muckelbauer, J.K.
Deposit date:2022-06-30
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.205 Å)
Cite:Structure-activity relationship (SAR) studies on substituted N-(pyridin-3-yl)-2-amino-isonicotinamides as highly potent and selective glycogen synthase kinase-3 (GSK-3) inhibitors.
Bioorg.Med.Chem.Lett., 81, 2023
8D1B
DownloadVisualize
BU of 8d1b by Molmil
CryoEM structure of human orphan GPCR GPR179 in complex with extracellular matrix protein pikachurin
Descriptor: Pikachurin, Probable G-protein coupled receptor 179
Authors:Patil, D.N, Martemyanov, K.A.
Deposit date:2022-05-27
Release date:2023-07-26
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.
Sci.Signal., 16, 2023
6D1W
DownloadVisualize
BU of 6d1w by Molmil
human PKD2 F604P mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystin-2
Authors:Zheng, W, Yang, X, Bulkley, D, Chen, X.Z, Cao, E.
Deposit date:2018-04-12
Release date:2018-06-27
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.
Nat Commun, 9, 2018
8YZ7
DownloadVisualize
BU of 8yz7 by Molmil
Crystal structure of DdrI, a CRP family protein from Deinococcus radiodurans
Descriptor: POTASSIUM ION, Transcriptional regulator, FNR/CRP family
Authors:Zhao, Y, Wang, Y.
Deposit date:2024-04-06
Release date:2024-07-03
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:cAMP-independent DNA binding of the CRP family protein DdrI from Deinococcus radiodurans.
Mbio, 15, 2024
8J6K
DownloadVisualize
BU of 8j6k by Molmil
Crystal structure of pro-interleukin-18 and caspase-4 complex
Descriptor: Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ...
Authors:Sun, Q, Hou, Y.J, Ding, J.
Deposit date:2023-04-26
Release date:2023-11-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome.
Nature, 624, 2023
3JUG
DownloadVisualize
BU of 3jug by Molmil
Crystal structure of endo-beta-1,4-mannanase from the alkaliphilic Bacillus sp. N16-5
Descriptor: Beta-mannanase, SULFATE ION
Authors:Zhao, Y, Zhang, Y, Xue, Y.
Deposit date:2009-09-15
Release date:2010-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure Analysis of Alkaline beta-mannanase from Alkaliphilic Bacillus sp. N16-5 Implications for Adaptation to Alkaline Conditions
To be Published
7XKS
DownloadVisualize
BU of 7xks by Molmil
Crystal structure of an alkaline pectate lyase from Bacillus clausii
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Pectate lyase
Authors:Zhou, C, Zheng, Y.Y, Liu, W.D, Ma, Y.
Deposit date:2022-04-20
Release date:2023-03-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of an Alkaline Pectate Lyase and Rational Engineering with Improved Thermo-Alkaline Stability for Efficient Ramie Degumming.
Int J Mol Sci, 24, 2022
8Y0R
DownloadVisualize
BU of 8y0r by Molmil
Complex of FMDV A/WH/CHA/09 and inter-serotype broadly neutralizing antibodies pOA-2
Descriptor: VP1 of capsid protein, VP2 of capsid protein, VP3 of capsid protein, ...
Authors:Wu, S, Lei, D.
Deposit date:2024-01-23
Release date:2024-10-09
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Discovery, evolution and recognizing antigenic structures of cross-serotype broadly neutralizing antibodies from porcine B-cell repertoires against foot-and-mouth disease virus
To Be Published
8Y0Q
DownloadVisualize
BU of 8y0q by Molmil
Complex of FMDV O/18074 and inter-serotype broadly neutralizing antibodies pOA-2
Descriptor: VP1 of capsid protein, VP2 of capsid protein, VP3 of capsid protein, ...
Authors:Wu, S, Lei, D.
Deposit date:2024-01-23
Release date:2024-10-09
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Discovery, evolution and recognizing antigenic structures of cross-serotype broadly neutralizing antibodies from porcine B-cell repertoires against foot-and-mouth disease virus
To Be Published
3NX2
DownloadVisualize
BU of 3nx2 by Molmil
Enterobacter sp. Px6-4 Ferulic Acid Decarboxylase in complex with substrate analogues
Descriptor: 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, Ferulic acid decarboxylase
Authors:Gu, W, Yang, J.K, Lou, Z.Y, Meng, Z.H, Zhang, K.-Q.
Deposit date:2010-07-12
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural Basis of Enzymatic Activity for the Ferulic Acid Decarboxylase (FADase) from Enterobacter sp. Px6-4
Plos One, 6, 2011
3NX1
DownloadVisualize
BU of 3nx1 by Molmil
Crystal structure of Enterobacter sp. Px6-4 Ferulic Acid Decarboxylase
Descriptor: Ferulic acid decarboxylase
Authors:Gu, W, Yang, J.K, Lou, Z.Y, Meng, Z.H, Zhang, K.-Q.
Deposit date:2010-07-12
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Enzymatic Activity for the Ferulic Acid Decarboxylase (FADase) from Enterobacter sp. Px6-4
Plos One, 6, 2011
8IQU
DownloadVisualize
BU of 8iqu by Molmil
Structure of MtbFadD23 with PhU-AMS
Descriptor: 5'-O-[(11-phenoxyundecanoyl)sulfamoyl]adenosine, Fatty-acid-CoA ligase FadD23
Authors:Yan, M.R, Zhang, W.
Deposit date:2023-03-17
Release date:2023-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for the development of potential inhibitors targeting FadD23 from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.F, 79, 2023
7XJF
DownloadVisualize
BU of 7xjf by Molmil
Crystal structure of 6MW3211 Fab in complex with CD47
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M, Wang, M.
Deposit date:2022-04-16
Release date:2023-05-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment.
Theranostics, 13, 2023
4Y2I
DownloadVisualize
BU of 4y2i by Molmil
Gold ion bound to GolB
Descriptor: GOLD ION, Putative metal-binding transport protein
Authors:Wei, W, Wang, F, Ma, L, Zhao, J.
Deposit date:2015-02-10
Release date:2016-02-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015
4Y2K
DownloadVisualize
BU of 4y2k by Molmil
reduced form of apo-GolB
Descriptor: Putative metal-binding transport protein
Authors:Wei, W, Wang, F, Ma, L, Zhao, J.
Deposit date:2015-02-10
Release date:2016-02-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015
4Y2M
DownloadVisualize
BU of 4y2m by Molmil
apo-GolB protein
Descriptor: GOLD ION, Putative metal-binding transport protein
Authors:Wei, W, Zhao, J, Wang, F.
Deposit date:2015-02-10
Release date:2016-02-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015
6KS5
DownloadVisualize
BU of 6ks5 by Molmil
Crystal structure of Legionella pneumophila deubiquitinase Ceg23
Descriptor: Type IV secretion protein Dot
Authors:Qiu, J.Z, Ouyang, S.Y.
Deposit date:2019-08-23
Release date:2020-01-15
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The bacterial deubiquitinase Ceg23 regulates the association of Lys-63-linked polyubiquitin molecules on theLegionellaphagosome.
J.Biol.Chem., 295, 2020
3CTZ
DownloadVisualize
BU of 3ctz by Molmil
Structure of human cytosolic X-prolyl aminopeptidase
Descriptor: CALCIUM ION, HEXAETHYLENE GLYCOL, MANGANESE (II) ION, ...
Authors:Li, X, Lou, Z, Rao, Z.
Deposit date:2008-04-15
Release date:2008-05-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of human cytosolic X-prolyl aminopeptidase: a double Mn(II)-dependent dimeric enzyme with a novel three-domain subunit
J.Biol.Chem., 283, 2008
3RZ2
DownloadVisualize
BU of 3rz2 by Molmil
Crystal of Prl-1 complexed with peptide
Descriptor: Prl-1 (PTP4A1), Protein tyrosine phosphatase type IVA 1
Authors:Zhang, Z.-Y, Liu, D, Bai, Y.
Deposit date:2011-05-11
Release date:2011-10-26
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.
J.Biol.Chem., 286, 2011
3PDV
DownloadVisualize
BU of 3pdv by Molmil
Structure of the PDlim2 PDZ domain in complex with the C-terminal 6-peptide extension of NS1
Descriptor: PDZ and LIM domain protein 2, C-teminal peptide from Nonstructural protein 1, SODIUM ION
Authors:Li, X.
Deposit date:2010-10-25
Release date:2011-09-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1
Plos One, 6, 2011
6AF0
DownloadVisualize
BU of 6af0 by Molmil
Structure of Ctr9, Paf1 and Cdc73 ternary complex from Myceliophthora thermophila
Descriptor: Cdc73 protein, Ctr9 protein, Paf1 protein
Authors:Wang, Z, Deng, P, Zhou, Y.
Deposit date:2018-08-07
Release date:2018-09-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6LOI
DownloadVisualize
BU of 6loi by Molmil
Crystal structure of Enterococcus faecalis Undecaprenyl pyrophosphate synthase(EfaUPPS)
Descriptor: Isoprenyl transferase
Authors:Lin, W, Wang, C.Y, Li, W.J, Wang, F.L.
Deposit date:2020-01-05
Release date:2020-06-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Investigations into the Antibacterial Mechanism of Action of Viridicatumtoxins.
Acs Infect Dis., 6, 2020
7REP
DownloadVisualize
BU of 7rep by Molmil
Crystal structure of an engineered variant of single-chain Penicillin G Acylase from Kluyvera cryocrescens (A1-Ac Rd3CHis)
Descriptor: CALCIUM ION, Penicillin G acylase, phenylmethanesulfonic acid
Authors:Orth, P.
Deposit date:2021-07-13
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.192 Å)
Cite:A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins.
Science, 376, 2022
7REO
DownloadVisualize
BU of 7reo by Molmil
Crystal structure of an engineered variant of single-chain Penicillin G Acylase from Kluyvera cryocrescens (global hydrolysis Rd3CHis)
Descriptor: CALCIUM ION, Penicillin G Acylase
Authors:Orth, P.
Deposit date:2021-07-13
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.812 Å)
Cite:A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins.
Science, 376, 2022
6JHY
DownloadVisualize
BU of 6jhy by Molmil
Crystal Structure of the S1 subunit N-terminal domain from DcCoV UAE-HKU23 spike protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein
Authors:Lu, G, Cheng, Y, Ye, F.
Deposit date:2019-02-19
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the S1 subunit N-terminal domain from DcCoV UAE-HKU23 spike protein.
Virology, 535, 2019

225946

數據於2024-10-09公開中

PDB statisticsPDBj update infoContact PDBjnumon