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8IEC
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BU of 8iec by Molmil
Cryo-EM structure of miniGo-scFv16 of GPR156-miniGo-scFv16 complex (local refine)
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ...
Authors:Shin, J, Park, J, Cho, Y.
Deposit date:2023-02-15
Release date:2024-02-14
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
8IEQ
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BU of 8ieq by Molmil
Cryo-EM structure of G-protein free GPR156
Descriptor: Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate
Authors:Shin, J, Park, J, Cho, Y.
Deposit date:2023-02-15
Release date:2024-02-14
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
8IEI
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BU of 8iei by Molmil
Cryo-EM structure of GPR156A/B of G-protein free GPR156 (local refine)
Descriptor: Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate
Authors:Shin, J, Park, J, Cho, Y.
Deposit date:2023-02-15
Release date:2024-02-14
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
8IEB
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BU of 8ieb by Molmil
Cryo-EM structure of GPR156 of GPR156-miniGo-scFv16 complex (local refine)
Descriptor: Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate
Authors:Shin, J, Park, J, Cho, Y.
Deposit date:2023-02-15
Release date:2024-02-14
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
8IEP
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BU of 8iep by Molmil
Cryo-EM structure of GPR156C/D of G-protein free GPR156 (local refine)
Descriptor: Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate
Authors:Shin, J, Park, J, Cho, Y.
Deposit date:2023-02-15
Release date:2024-02-14
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
6Q0D
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BU of 6q0d by Molmil
CRYSTAL STRUCTURE OF LDHA IN COMPLEX WITH COMPOUND NCGC00384414-01 AT 2.05 A RESOLUTION
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-{3-[3-(cyclopentylethynyl)-4-fluorophenyl]-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, GLYCEROL, ...
Authors:Dranow, D.M, Davies, D.R.
Deposit date:2019-08-01
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties.
J.Med.Chem., 63, 2020
6Q13
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BU of 6q13 by Molmil
CRYSTAL STRUCTURE OF LDHA IN COMPLEX WITH COMPOUND NCGC00420737-09 AT 2.00 A RESOLUTION
Descriptor: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-[5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-3-{3-[(5-methylthiophen-2-yl)ethynyl]phenyl}-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid, ...
Authors:Davies, D.R, Dranow, D.M.
Deposit date:2019-08-02
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties.
J.Med.Chem., 63, 2020
8IED
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BU of 8ied by Molmil
Cryo-EM structure of GPR156-miniGo-scFv16 complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ...
Authors:Shin, J, Park, J, Cho, Y.
Deposit date:2023-02-15
Release date:2024-02-14
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
8EL2
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BU of 8el2 by Molmil
SARS-CoV-2 RBD bound to neutralizing antibody Fab ICO-hu23
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab ICO-hu23 Heavy Chain, Fab ICO-hu23 Light Chain, ...
Authors:Besaw, J.E, Kuo, A, Morizumi, T, Ernst, O.P.
Deposit date:2022-09-22
Release date:2023-07-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates.
Plos Pathog., 19, 2023
7F1W
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BU of 7f1w by Molmil
X-ray crystal structure of visual arrestin complexed with inositol hexaphosphate
Descriptor: INOSITOL HEXAKISPHOSPHATE, S-arrestin
Authors:Kang, M, Jang, K, Eger, B.T, Ernst, O.P, Choe, H.W, Kim, Y.J.
Deposit date:2021-06-10
Release date:2021-10-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.097 Å)
Cite:Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
7F1X
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BU of 7f1x by Molmil
X-ray crystal structure of visual arrestin complexed with inositol 1,4,5-triphosphate
Descriptor: 1,2-ETHANEDIOL, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, PENTANEDIAL, ...
Authors:Jang, K, Kang, M, Eger, B.T, Choe, H.W, Ernst, O.P, Kim, Y.J.
Deposit date:2021-06-10
Release date:2021-10-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
4B18
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BU of 4b18 by Molmil
The crystal structure of human Importin alpha 5 with TERT NLS peptide
Descriptor: IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE TRANSCRIPTASE
Authors:Kim, K.L, Yoo, J.H, Cho, H.S.
Deposit date:2012-07-08
Release date:2013-09-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Akt-Mediated Phosphorylation Increases the Binding Affinity of Htert for Importin Alpha to Promote Nuclear Translocation.
J.Cell.Sci., 128, 2015
7S8L
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BU of 7s8l by Molmil
CryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14
Descriptor: Cortistatin 14, Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Cao, C, Fay, J.F, Gumpper, R.H, Roth, B.L.
Deposit date:2021-09-18
Release date:2021-11-17
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Structure, function and pharmacology of human itch GPCRs.
Nature, 600, 2021
7S8N
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BU of 7s8n by Molmil
CryoEM structure of Gq-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Descriptor: (3R)-N,N-dimethyl-1-[(8S)-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl]pyrrolidin-3-amine, Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Cao, C, Fay, J.F, Gumpper, R.H, Roth, B.L.
Deposit date:2021-09-18
Release date:2021-11-17
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure, function and pharmacology of human itch GPCRs.
Nature, 600, 2021
7S8O
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BU of 7s8o by Molmil
CryoEM structure of Gi-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Descriptor: (3R)-N,N-dimethyl-1-[(8S)-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl]pyrrolidin-3-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Cao, C, Fay, J.F, Gumpper, R.H, Roth, B.L.
Deposit date:2021-09-18
Release date:2021-11-17
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Structure, function and pharmacology of human itch GPCRs.
Nature, 600, 2021
7S8P
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BU of 7s8p by Molmil
CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134
Descriptor: Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Cao, C, Fay, J.F, Gumpper, R.H, Roth, B.L.
Deposit date:2021-09-18
Release date:2021-11-17
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure, function and pharmacology of human itch GPCRs.
Nature, 600, 2021
7S8M
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BU of 7s8m by Molmil
CryoEM structure of Gi-coupled MRGPRX2 with peptide agonist Cortistatin-14
Descriptor: Cortistatin 14, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Cao, C, Fay, J.F, Gumpper, R.H, Roth, B.L.
Deposit date:2021-09-18
Release date:2021-11-17
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Structure, function and pharmacology of human itch GPCRs.
Nature, 600, 2021
4ML7
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BU of 4ml7 by Molmil
Crystal structure of Brucella abortus PliC in complex with human lysozyme
Descriptor: Humanlysozyme, Lysozyme C
Authors:Ha, N.C, Um, S.H, Kim, J.S.
Deposit date:2013-09-06
Release date:2014-07-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for the Inhibition of Human Lysozyme by PliC from Brucella abortus
Biochemistry, 52, 2013
4MIR
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BU of 4mir by Molmil
The structure of Brucella abortus PliC in the hexagonal crystal form
Descriptor: Putative uncharacterized protein
Authors:Ha, N.C, Um, S.H, Kim, J.S.
Deposit date:2013-09-02
Release date:2014-07-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the inhibition of human lysozyme by PliC from Brucella abortus
Biochemistry, 52, 2013
4MIS
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BU of 4mis by Molmil
The structure of Brucella abortus PliC in the orthorombic crystal form
Descriptor: Putative uncharacterized protein
Authors:Ha, N.C, Um, S.H, Kim, J.S.
Deposit date:2013-09-02
Release date:2014-07-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the inhibition of human lysozyme by PliC from Brucella abortus
Biochemistry, 52, 2013
6LKS
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BU of 6lks by Molmil
Effects of zinc ion on oligomerization and pH stability of influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Seok, J, Kim, K.
Deposit date:2019-12-20
Release date:2020-10-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Divalent cation-induced conformational changes of influenza virus hemagglutinin.
Sci Rep, 10, 2020
4ZJV
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BU of 4zjv by Molmil
crystal structure of EGFR kinase domain in complex with Mitogen-inducible gene 6 protein
Descriptor: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor
Authors:Eck, M.J, Park, E, Lee, B.
Deposit date:2015-04-29
Release date:2015-08-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6.
Nat.Struct.Mol.Biol., 22, 2015
6ICI
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BU of 6ici by Molmil
Crystal structure of human MICAL3
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, [F-actin]-monooxygenase MICAL3
Authors:Hwang, K.Y, Kim, J.S.
Deposit date:2018-09-06
Release date:2020-03-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3.
Iucrj, 7, 2020
2RVC
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BU of 2rvc by Molmil
Solution structure of Zalpha domain of goldfish ZBP-containing protein kinase
Descriptor: Interferon-inducible and double-stranded-dependent eIF-2kinase
Authors:Lee, A, Park, C, Park, J, Kwon, M, Choi, Y, Kim, K, Choi, B, Lee, J.
Deposit date:2015-07-08
Release date:2016-02-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the Z-DNA binding domain of PKR-like protein kinase from Carassius auratus and quantitative analyses of the intermediate complex during B-Z transition.
Nucleic Acids Res., 44, 2016
7LJX
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BU of 7ljx by Molmil
Oxidized rat cytochrome c mutant (K53Q)
Descriptor: Cytochrome c, somatic, HEME C, ...
Authors:Huttemann, M, Edwards, B.F.P, Brunzelle, J.S, Vaishnav, A.
Deposit date:2021-02-01
Release date:2021-05-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Lysine 53 Acetylation of Cytochrome c in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis.
Cells, 10, 2021

221051

數據於2024-06-12公開中

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