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7ZCF
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BU of 7zcf by Molmil
SARS-CoV-2 Spike RBD in complex with the single chain fragment scFv76 (Focused Refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, scFv76 single chain fragment
Authors:Chaves-Sanjuan, A, Bolognesi, M.
Deposit date:2022-03-28
Release date:2022-10-12
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery.
Mol.Ther., 31, 2022
7Z60
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BU of 7z60 by Molmil
Human transthyretin (TTR) complexed with Quercetin 3-O-beta-D-galactoside
Descriptor: 1,2-ETHANEDIOL, 2-[3,4-bis(oxidanyl)phenyl]-3-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5,7-bis(oxidanyl)chromen-4-one, IMIDAZOLE, ...
Authors:Ciccone, L, Braca, A, Orlandini, E, Nencetti, S.
Deposit date:2022-03-10
Release date:2022-05-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization
Crystals, 12, 2022
8BP0
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BU of 8bp0 by Molmil
Crystal structure of BHMeHis1.8, an engineered enzyme for the Morita-Baylis-Hillman reaction
Descriptor: 1,2-ETHANEDIOL, BHMeHis1.8, TRIETHYLENE GLYCOL
Authors:Hardy, F.J.
Deposit date:2022-11-15
Release date:2024-02-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.621 Å)
Cite:A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme.
Nat Commun, 15, 2024
8BP1
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BU of 8bp1 by Molmil
Crystal structure of BHMeHis1.0, an engineered enzyme for the Morita-Baylis-Hillman reaction
Descriptor: ACETATE ION, BHMeHis1.0, DI(HYDROXYETHYL)ETHER, ...
Authors:Hardy, F.J.
Deposit date:2022-11-15
Release date:2024-02-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme.
Nat Commun, 15, 2024
7QG0
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BU of 7qg0 by Molmil
Inhibitor-induced hSARM1 duplex
Descriptor: NAD(+) hydrolase SARM1
Authors:Zalk, R, Kahzma, T, Guez-Haddad, J.
Deposit date:2021-12-07
Release date:2022-12-21
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:A duplex structure of SARM1 octamers stabilized by a new inhibitor.
Cell.Mol.Life Sci., 80, 2022
8QE8
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BU of 8qe8 by Molmil
Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to NMNAT1 substrate
Descriptor: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1, WD repeat-containing protein 26, ...
Authors:Chrustowicz, J, Sherpa, D, Schulman, B.A.
Deposit date:2023-08-30
Release date:2024-05-15
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism.
Mol.Cell, 84, 2024
8QBN
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BU of 8qbn by Molmil
Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to YPEL5
Descriptor: Protein yippee-like 5, WD repeat-containing protein 26, ZINC ION
Authors:Chrustowicz, J, Sherpa, D, Schulman, B.A.
Deposit date:2023-08-24
Release date:2024-05-15
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism.
Mol.Cell, 84, 2024
8P2L
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BU of 8p2l by Molmil
A CHIMERA construct containing human SARM1 ARM and SAM domains and C. elegans TIR domain.
Descriptor: NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Isupov, M.N, Opatowsky, Y.
Deposit date:2023-05-16
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
8P2M
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BU of 8p2m by Molmil
C. elegans TIR-1 protein.
Descriptor: NAD(+) hydrolase tir-1
Authors:Isupov, M.N, Opatowsky, Y.
Deposit date:2023-05-16
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.82 Å)
Cite:Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023

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數據於2024-07-03公開中

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