3VBR
| Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (room temperature) | Descriptor: | Genome Polyprotein, capsid protein VP0, capsid protein VP1, ... | Authors: | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | Deposit date: | 2012-01-02 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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3VCB
| C425S mutant of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59 | Descriptor: | RNA-directed RNA polymerase | Authors: | Xu, X, Lou, Z, Ma, Y, Chen, X, Yang, Z, Tong, X, Zhao, Q, Xu, Y, Deng, H, Bartlam, M, Rao, Z. | Deposit date: | 2012-01-03 | Release date: | 2012-01-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59. Plos One, 4, 2009
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3VBF
| Crystal structure of formaldehyde treated human Enterovirus 71 (space group I23) | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Genome Polyprotein, ... | Authors: | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | Deposit date: | 2012-01-02 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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3VBO
| Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (cryo at 100K) | Descriptor: | Genome Polyprotein, capsid protein VP1, capsid protein VP2, ... | Authors: | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | Deposit date: | 2012-01-02 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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6M0K
| The crystal structure of COVID-19 main protease in complex with an inhibitor 11b | Descriptor: | 3C-like proteinase, DIMETHYL SULFOXIDE, ~{N}-[(2~{S})-3-(3-fluorophenyl)-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide | Authors: | Zhang, B, Zhao, Y, Jin, Z, Liu, X, Yang, H, Liu, H, Rao, Z, Jiang, H. | Deposit date: | 2020-02-22 | Release date: | 2020-04-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.504 Å) | Cite: | Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. Science, 368, 2020
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3VC8
| Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59 | Descriptor: | RNA-directed RNA polymerase | Authors: | Xu, X, Lou, Z, Ma, Y, Chen, X, Yang, Z, Tong, X, Zhao, Q, Xu, Y, Deng, H, Bartlam, M, Rao, Z. | Deposit date: | 2012-01-03 | Release date: | 2012-01-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59. Plos One, 4, 2009
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5ABJ
| Structure of Coxsackievirus A16 in complex with GPP3 | Descriptor: | 1-[(3S)-5-[4-[(E)-ETHOXYIMINOMETHYL]PHENOXY]-3-METHYL-PENTYL]-3-PYRIDIN-4-YL-IMIDAZOLIDIN-2-ONE, CHLORIDE ION, SODIUM ION, ... | Authors: | De Colibus, L, Wang, X, Tijsma, A, Neyts, J, Spyrou, J.A.B, Ren, J, Grimes, J.M, Puerstinger, G, Leyssen, P, Fry, E.E, Rao, Z, Stuart, D.I. | Deposit date: | 2015-08-06 | Release date: | 2015-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure Elucidation of Coxsackievirus A16 in Complex with Gpp3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses. Plos Pathog., 11, 2015
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3VBS
| Crystal structure of human Enterovirus 71 | Descriptor: | Genome Polyprotein, capsid protein VP1, capsid protein VP2, ... | Authors: | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | Deposit date: | 2012-01-02 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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3VBU
| Crystal structure of empty human Enterovirus 71 particle | Descriptor: | Genome Polyprotein, capsid protein VP0, capsid protein VP1, ... | Authors: | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | Deposit date: | 2012-01-02 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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2GTH
| crystal structure of the wildtype MHV coronavirus non-structural protein nsp15 | Descriptor: | Replicase polyprotein 1ab | Authors: | Xu, X, Zhai, Y, Sun, F, Lou, Z, Su, D, Rao, Z. | Deposit date: | 2006-04-28 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | New Antiviral Target Revealed by the Hexameric Structure of Mouse Hepatitis Virus Nonstructural Protein nsp15 J.Virol., 80, 2006
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1UEF
| Crystal Structure of Dok1 PTB Domain Complex | Descriptor: | 13-mer peptide from Proto-oncogene tyrosine-protein kinase receptor ret, Docking protein 1 | Authors: | Shi, N, Ye, S, Liu, Y, Zhou, W, Ding, Y, Lou, Z, Qiang, B, Yan, J, Rao, Z. | Deposit date: | 2003-05-14 | Release date: | 2004-05-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain J.Biol.Chem., 279, 2004
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2IS9
| Structure of yeast DCN-1 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Defective in cullin neddylation protein 1, ... | Authors: | Yang, X, Zhou, J, Sun, L, Wei, Z, Gao, J, Gong, W, Xu, R.M, Rao, Z, Liu, Y. | Deposit date: | 2006-10-16 | Release date: | 2007-06-26 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural basis for the function of DCN-1 in protein Neddylation. J.Biol.Chem., 282, 2007
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2G9T
| Crystal structure of the SARS coronavirus nsp10 at 2.1A | Descriptor: | ZINC ION, orf1a polyprotein | Authors: | Su, D, Lou, Z, Yang, H, Sun, F, Rao, Z. | Deposit date: | 2006-03-07 | Release date: | 2006-08-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein nsp10 J.Virol., 80, 2006
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2AHM
| Crystal structure of SARS-CoV super complex of non-structural proteins: the hexadecamer | Descriptor: | GLYCEROL, Replicase polyprotein 1ab, heavy chain, ... | Authors: | Zhai, Y.J, Sun, F, Bartlam, M, Rao, Z. | Deposit date: | 2005-07-28 | Release date: | 2005-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Insights into SARS-CoV transcription and replication from the structure of the nsp7-nsp8 hexadecamer NAT.STRUCT.MOL.BIOL., 12, 2005
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2GTI
| mutation of MHV coronavirus non-structural protein nsp15 (F307L) | Descriptor: | GLYCEROL, Replicase polyprotein 1ab, SULFATE ION | Authors: | Xu, X, Zhai, Y, Sun, F, Lou, Z, Su, D, Rao, Z. | Deposit date: | 2006-04-28 | Release date: | 2006-08-15 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | New Antiviral Target Revealed by the Hexameric Structure of Mouse Hepatitis Virus Nonstructural Protein nsp15 J.Virol., 80, 2006
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2GA6
| The crystal structure of SARS nsp10 without zinc ion as additive | Descriptor: | ZINC ION, orf1a polyprotein | Authors: | Su, D, Lou, Z, Sun, F, Zhai, Y, Yang, H, Rao, Z. | Deposit date: | 2006-03-08 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein nsp10 J.Virol., 80, 2006
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6L2T
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3CTZ
| Structure of human cytosolic X-prolyl aminopeptidase | Descriptor: | CALCIUM ION, HEXAETHYLENE GLYCOL, MANGANESE (II) ION, ... | Authors: | Li, X, Lou, Z, Rao, Z. | Deposit date: | 2008-04-15 | Release date: | 2008-05-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of human cytosolic X-prolyl aminopeptidase: a double Mn(II)-dependent dimeric enzyme with a novel three-domain subunit J.Biol.Chem., 283, 2008
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3G36
| Crystal structure of the human DPY-30-like C-terminal domain | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... | Authors: | Wang, X, Lou, Z, Bartlam, M, Rao, Z. | Deposit date: | 2009-02-02 | Release date: | 2009-06-30 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal structure of the C-terminal domain of human DPY-30-like protein: A component of the histone methyltransferase complex J.Mol.Biol., 390, 2009
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1J55
| The Crystal Structure of Ca+-bound Human S100P Determined at 2.0A Resolution by X-ray | Descriptor: | CALCIUM ION, S-100P PROTEIN | Authors: | Zhang, H, Wang, G, Ding, Y, Wang, Z, Barraclough, R, Rudland, P.S, Fernig, D.G, Rao, Z. | Deposit date: | 2002-01-25 | Release date: | 2003-01-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Crystal Structure at 2A Resolution of the Ca2+-binding Protein S100P J.Mol.Biol., 325, 2003
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5GNS
| Structures of human Mitofusin 1 provide insight into mitochondrial tethering | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Mitofusin-1 | Authors: | Qi, Y, Yan, L, Yu, C, Guo, X, Zhou, X, Hu, X, Huang, X, Rao, Z, Lou, Z, Hu, J. | Deposit date: | 2016-07-24 | Release date: | 2016-12-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | Structures of human Mitofusin 1 provide insight into mitochondrial tethering To Be Published
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1WNC
| Crystal structure of the SARS-CoV Spike protein fusion core | Descriptor: | E2 glycoprotein | Authors: | Xu, Y, Lou, Z, Liu, Y, Pang, H, Tien, P, Gao, G.F, Rao, Z. | Deposit date: | 2004-07-29 | Release date: | 2004-09-07 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core J.Biol.Chem., 279, 2004
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1GHE
| CRYSTAL STRUCTURE OF TABTOXIN RESISTANCE PROTEIN COMPLEXED WITH AN ACYL COENZYME A | Descriptor: | ACETYL COENZYME *A, ACETYLTRANSFERASE | Authors: | He, H, Ding, Y, Bartlam, M, Sun, F, Le, Y, Qin, X, Tang, H, Zhang, R, Joachimiak, A, Liu, Y, Zhao, N, Rao, Z. | Deposit date: | 2000-12-13 | Release date: | 2003-01-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal Structure of Tabtoxin Resistance Protein Complexed with Acetyl
Coenzyme A Reveals the Mechanism for beta-Lactam Acetylation J.Mol.Biol., 325, 2003
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1GIU
| A TRICHOSANTHIN(TCS) MUTANT(E85R) COMPLEX STRUCTURE WITH ADENINE | Descriptor: | ADENINE, RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN | Authors: | Guo, Q, Liu, Y, Dong, Y, Rao, Z. | Deposit date: | 2001-03-15 | Release date: | 2003-06-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants. Protein Eng., 16, 2003
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1YP1
| Crystal structure of a non-hemorrhagic fibrin(ogen)olytic metalloproteinase from venom of Agkistrodon acutus | Descriptor: | FII, KNL, ZINC ION | Authors: | Lou, Z, Hou, J, Chen, J, Liang, X, Qiu, P, Liu, Y, Li, M, Rao, Z. | Deposit date: | 2005-01-28 | Release date: | 2006-01-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a non-hemorrhagic fibrin(ogen)olytic metalloproteinase complexed with a novel natural tri-peptide inhibitor from venom of Agkistrodon acutus J.Struct.Biol., 152, 2005
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