5Y1U
 
 | | Crystal structure of RBBP4 bound to AEBP2 RRK motif | | Descriptor: | Histone-binding protein RBBP4, SULFATE ION, Zinc finger protein AEBP2 | | Authors: | Sun, A, Li, F, Wu, J, Shi, Y. | | Deposit date: | 2017-07-21 | | Release date: | 2018-04-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.141 Å) | | Cite: | Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4
Protein Cell, 2017
|
|
6XSW
 | | Structure of the Notch3 NRR in complex with an antibody Fab Fragment | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-N3 Fab Heavy Chain, ... | | Authors: | Bard, J. | | Deposit date: | 2020-07-16 | | Release date: | 2021-07-21 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells.
Cell Rep Med, 2, 2021
|
|
9CSY
 | | SARS-CoV-2 papain-like protease (PLpro) bound to PF-07957472 | | Descriptor: | 2-methyl-5-(4-methylpiperazin-1-yl)-N-{1-[(2P)-2-(1-methyl-1H-pyrazol-4-yl)quinolin-4-yl]cyclopropyl}benzamide, Papain-like protease, ZINC ION, ... | | Authors: | Mashalidis, E.H, Chang, J.S, Wu, H, Garnsey, M. | | Deposit date: | 2024-07-24 | | Release date: | 2024-10-02 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.595 Å) | | Cite: | Discovery of SARS-CoV-2 papain-like protease (PL pro ) inhibitors with efficacy in a murine infection model.
Sci Adv, 10, 2024
|
|
5YJH
 | | Structural insights into periostin functions | | Descriptor: | CALCIUM ION, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Liu, H, Liu, J, Xu, F. | | Deposit date: | 2017-10-10 | | Release date: | 2018-05-23 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.957 Å) | | Cite: | Structural characterizations of human periostin dimerization and cysteinylation.
FEBS Lett., 592, 2018
|
|
5WF0
 | |
5WFK
 | |
4OU4
 | | Crystal structure of esterase rPPE mutant S159A complexed with (S)-Ac-CPA | | Descriptor: | (2S)-(acetyloxy)(2-chlorophenyl)ethanoic acid, Alpha/beta hydrolase fold-3 domain protein | | Authors: | Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H. | | Deposit date: | 2014-02-15 | | Release date: | 2014-07-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
|
|
5WFS
 | |
6NPL
 | | Cryo-EM structure of NKCC1 | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ... | | Authors: | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | | Deposit date: | 2019-01-17 | | Release date: | 2019-07-31 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
|
|
6NPH
 | | Structure of NKCC1 TM domain | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ... | | Authors: | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | | Deposit date: | 2019-01-17 | | Release date: | 2019-07-31 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
|
|
5EIG
 | |
5YJG
 | | Structural insights into periostin functions | | Descriptor: | CALCIUM ION, CHLORIDE ION, CYSTEINE, ... | | Authors: | Liu, H, Liu, J, Xu, F. | | Deposit date: | 2017-10-10 | | Release date: | 2018-05-23 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.399 Å) | | Cite: | Structural characterizations of human periostin dimerization and cysteinylation.
FEBS Lett., 592, 2018
|
|
7ULI
 | | Apo HMG-CoA Reductase from Arabidopsis thaliana (HMG1) | | Descriptor: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 | | Authors: | Haywood, J, Bond, C.S. | | Deposit date: | 2022-04-05 | | Release date: | 2022-05-18 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A fungal tolerance trait and selective inhibitors proffer HMG-CoA reductase as a herbicide mode-of-action.
Nat Commun, 13, 2022
|
|
4QVC
 | | E.coli Hfq in complex with RNA Aus | | Descriptor: | RNA (5'-R(*AP*U*AP*AP*CP*UP*A)-3'), RNA-binding protein Hfq | | Authors: | Wang, L.J, Wang, W.W, Li, F.D, Wu, J.H, Gong, Q.G, Shi, Y.Y. | | Deposit date: | 2014-07-14 | | Release date: | 2015-05-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq
Nucleic Acids Res., 43, 2015
|
|
5Y0U
 | | The solution structure of AEBP2 C2H2 zinc fingers | | Descriptor: | ZINC ION, Zinc finger protein AEBP2 | | Authors: | Sun, A, Shi, Y, Wu, J. | | Deposit date: | 2017-07-18 | | Release date: | 2018-08-01 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4.
Protein Cell, 9, 2018
|
|
8BYP
 | |
3SWJ
 | | Crystal structure of Campylobacter jejuni ChuZ | | Descriptor: | AZIDE ION, PROTOPORPHYRIN IX CONTAINING FE, Putative uncharacterized protein | | Authors: | Hu, Y. | | Deposit date: | 2011-07-14 | | Release date: | 2011-11-09 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.409 Å) | | Cite: | Crystal structure of Campylobacter jejuni ChuZ: a split-barrel family heme oxygenase with a novel heme-binding mode.
Biochem.Biophys.Res.Commun., 415, 2011
|
|
4QVD
 | | E.coli Hfq in complex with RNA Ads | | Descriptor: | RNA (5'-R(*AP*AP*CP*UP*AP*AP*A)-3'), RNA-binding protein Hfq | | Authors: | Wang, L.J, Wang, W.W, Li, F.D, Wu, J.H, Gong, Q.G, Shi, Y.Y. | | Deposit date: | 2014-07-14 | | Release date: | 2015-05-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.972 Å) | | Cite: | Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq
Nucleic Acids Res., 43, 2015
|
|
4IOU
 | |
2EW7
 | | Crystal Structure of Helicobacter Pylori peptide deformylase | | Descriptor: | COBALT (II) ION, peptide deformylase | | Authors: | Cai, J. | | Deposit date: | 2005-11-02 | | Release date: | 2006-10-24 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation
Protein Sci., 15, 2006
|
|
2EW6
 | | Structure of Helicobacter Pylori peptide deformylase in complex with inhibitor | | Descriptor: | (2E)-3-(3,4-DIHYDROXYPHENYL)-N-[2-(4-HYDROXYPHENYL)ETHYL]ACRYLAMIDE, COBALT (II) ION, peptide deformylase | | Authors: | Cai, J. | | Deposit date: | 2005-11-02 | | Release date: | 2006-10-24 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation
Protein Sci., 15, 2006
|
|
4RSE
 | | Crystal structure of RPE65 in complex with MB-001 and palmitate | | Descriptor: | (1R)-3-amino-1-{3-[(2,6,6-trimethylcyclohex-1-en-1-yl)methoxy]phenyl}propan-1-ol, FE (II) ION, PALMITIC ACID, ... | | Authors: | Kiser, P.D, Shi, W, Palczewski, K. | | Deposit date: | 2014-11-07 | | Release date: | 2015-04-15 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat.Chem.Biol., 11, 2015
|
|
2EW5
 | | Structure of Helicobacter Pylori peptide deformylase in complex with inhibitor | | Descriptor: | 4-{(1E)-3-OXO-3-[(2-PHENYLETHYL)AMINO]PROP-1-EN-1-YL}-1,2-PHENYLENE DIACETATE, COBALT (II) ION, peptide deformylase | | Authors: | Cai, J. | | Deposit date: | 2005-11-02 | | Release date: | 2006-10-24 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation
Protein Sci., 15, 2006
|
|
8KCI
 | | ATP-bound hMRP5 outward-open | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 5, MAGNESIUM ION | | Authors: | Liu, Z.M, Huang, Y. | | Deposit date: | 2023-08-07 | | Release date: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.94 Å) | | Cite: | Inhibition and transport mechanisms of the ABC transporter hMRP5.
Nat Commun, 15, 2024
|
|
5XK0
 | | Structure of 8-mer DNA2 | | Descriptor: | DNA (5'-D(*GP*CP*CP*CP*GP*AP*GP*C)-3') | | Authors: | Liu, H.H, Gan, J.H. | | Deposit date: | 2017-05-04 | | Release date: | 2017-12-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.451 Å) | | Cite: | A DNA Structure Containing AgI -Mediated G:G and C:C Base Pairs
Angew. Chem. Int. Ed. Engl., 56, 2017
|
|
