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2F1Y
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BU of 2f1y by Molmil
Crystal structure of the TRAF-like domain of HAUSP/USP7 bound to a MDM2 peptide
Descriptor: HAUSP/USP7
Authors:Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
Deposit date:2005-11-15
Release date:2006-02-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
2F1X
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BU of 2f1x by Molmil
Crystal structure of the TRAF-like domain of HAUSP/USP7 bound to a p53 peptide
Descriptor: HAUSP/USP7
Authors:Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
Deposit date:2005-11-15
Release date:2006-02-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
4JC8
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BU of 4jc8 by Molmil
Crystal Structure of HOPS component Vps33 from Chaetomium thermophilum
Descriptor: HOPS component Vps33
Authors:Baker, R.W, Jeffrey, P.D, Hughson, F.M.
Deposit date:2013-02-21
Release date:2013-05-08
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*
Plos One, 8, 2013
4H5J
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BU of 4h5j by Molmil
Crystal Structure of the Guanine Nucleotide Exchange Factor Sec12 (P64 form)
Descriptor: Guanine nucleotide-exchange factor SEC12, POTASSIUM ION
Authors:McMahon, C, Jeffrey, P.D, Hughson, F.M.
Deposit date:2012-09-18
Release date:2012-11-07
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:The structure of sec12 implicates potassium ion coordination in sar1 activation.
J.Biol.Chem., 287, 2012
4I5K
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BU of 4i5k by Molmil
PP2A PR70 Holoenzyme model3_diCa_rcsb.pdb bppnat5_extend.mtz
Descriptor: CALCIUM ION, Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Authors:Xing, Y, Jeffrey, P.D, Shi, Y.
Deposit date:2012-11-28
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
4H5I
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BU of 4h5i by Molmil
Crystal Structure of the Guanine Nucleotide Exchange Factor Sec12 (P1 form)
Descriptor: Guanine nucleotide-exchange factor SEC12, POTASSIUM ION
Authors:McMahon, C, Jeffrey, P.D, Hughson, F.M.
Deposit date:2012-09-18
Release date:2012-11-07
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:The structure of sec12 implicates potassium ion coordination in sar1 activation.
J.Biol.Chem., 287, 2012
4KMO
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BU of 4kmo by Molmil
Crystal Structure of the Vps33-Vps16 HOPS subcomplex from Chaetomium thermophilum
Descriptor: Putative vacuolar protein sorting-associated protein, SULFATE ION, Small conjugating protein ligase-like protein
Authors:Baker, R.W, Jeffrey, P.D, Hughson, F.M.
Deposit date:2013-05-08
Release date:2013-06-26
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*
Plos One, 8, 2013
4I1A
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BU of 4i1a by Molmil
Crystal Structure of the Apo Form of RapI
Descriptor: CHLORIDE ION, Response regulator aspartate phosphatase I
Authors:Parashar, V, Jeffrey, P.D, Neiditch, M.B.
Deposit date:2012-11-20
Release date:2013-04-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.443 Å)
Cite:Conformational change-induced repeat domain expansion regulates rap phosphatase quorum-sensing signal receptors.
Plos Biol., 11, 2013
1JST
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BU of 1jst by Molmil
PHOSPHORYLATED CYCLIN-DEPENDENT KINASE-2 BOUND TO CYCLIN A
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN A, CYCLIN-DEPENDENT KINASE-2, ...
Authors:Russo, A.A, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1996-07-03
Release date:1997-01-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of cyclin-dependent kinase activation by phosphorylation.
Nat.Struct.Biol., 3, 1996
1CEV
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BU of 1cev by Molmil
ARGINASE FROM BACILLUS CALDOVELOX, NATIVE STRUCTURE AT PH 5.6
Descriptor: MANGANESE (II) ION, PROTEIN (ARGINASE)
Authors:Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N.
Deposit date:1999-03-12
Release date:1999-04-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
1BI7
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BU of 1bi7 by Molmil
MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX
Descriptor: CYCLIN-DEPENDENT KINASE 6, MULTIPLE TUMOR SUPPRESSOR
Authors:Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1998-06-22
Release date:1999-01-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
1BI8
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BU of 1bi8 by Molmil
MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX
Descriptor: CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE INHIBITOR
Authors:Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1998-06-22
Release date:1999-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
Nature, 395, 1998
3IA3
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BU of 3ia3 by Molmil
A cis-proline in alpha-hemoglobin stabilizing Protein directs the structural reorganization of alpha-hemoglobin
Descriptor: Alpha-hemoglobin-stabilizing protein, Hemoglobin subunit alpha, PROTOPORPHYRIN IX CONTAINING FE
Authors:Feng, L, Jeffrey, P.D, Shi, Y.
Deposit date:2009-07-13
Release date:2009-07-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A cis-proline in alpha-hemoglobin stabilizing protein directs the structural reorganization of alpha-hemoglobin.
J.Biol.Chem., 284, 2009
3KKI
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BU of 3kki by Molmil
PLP-Dependent Acyl-CoA transferase CqsA
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CAI-1 autoinducer synthase, MAGNESIUM ION, ...
Authors:Kelly, R.C, Jeffrey, P.D, Hughson, F.M.
Deposit date:2009-11-05
Release date:2009-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.
Nat.Chem.Biol., 5, 2009
3K8P
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BU of 3k8p by Molmil
Structural basis for vesicle tethering by the Dsl1 complex
Descriptor: Dsl1, Protein transport protein SEC39
Authors:Ren, Y, Jeffrey, P.D, Hughson, F.M.
Deposit date:2009-10-14
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1.
Cell(Cambridge,Mass.), 139, 2009
3HQT
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BU of 3hqt by Molmil
PLP-Dependent Acyl-CoA Transferase CqsA
Descriptor: CAI-1 autoinducer synthase, PYRIDOXAL-5'-PHOSPHATE
Authors:Kelly, R.C, Jeffrey, P.D, Hughson, F.M.
Deposit date:2009-06-08
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.
Nat.Chem.Biol., 5, 2009
3HR0
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BU of 3hr0 by Molmil
Crystal structure of Homo sapiens Conserved Oligomeric Golgi subunit 4
Descriptor: CoG4
Authors:Richardson, B.C, Ungar, D, Nakamura, A, Jeffrey, P.D, Hughson, F.M.
Deposit date:2009-06-08
Release date:2009-07-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene.
Proc.Natl.Acad.Sci.USA, 106, 2009
3C5W
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BU of 3c5w by Molmil
Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme
Descriptor: PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1
Authors:Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y.
Deposit date:2008-02-01
Release date:2008-04-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural mechanism of demethylation and inactivation of protein phosphatase 2A.
Cell(Cambridge,Mass.), 133, 2008
3BOE
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BU of 3boe by Molmil
Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2 with acetate (CDCA1-R2)
Descriptor: ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase
Authors:Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M.
Deposit date:2007-12-17
Release date:2008-01-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
3C5V
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BU of 3c5v by Molmil
PP2A-specific methylesterase apo form (PME)
Descriptor: Protein phosphatase methylesterase 1
Authors:Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y.
Deposit date:2008-02-01
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural mechanism of demethylation and inactivation of protein phosphatase 2A.
Cell(Cambridge,Mass.), 133, 2008
3BOJ
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BU of 3boj by Molmil
Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 without bound metal (CDCA1-R1)
Descriptor: ACETATE ION, Cadmium-specific carbonic anhydrase
Authors:Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M.
Deposit date:2007-12-17
Release date:2008-01-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
3BOB
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BU of 3bob by Molmil
Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2
Descriptor: CADMIUM ION, Cadmium-specific carbonic anhydrase
Authors:Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M.
Deposit date:2007-12-17
Release date:2008-01-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
3BOC
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BU of 3boc by Molmil
Carbonic anhydrase from marine diatom Thalassiosira weissflogii- zinc bound domain 2 (CDCA1-R2)
Descriptor: Cadmium-specific carbonic anhydrase, ZINC ION
Authors:Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M.
Deposit date:2007-12-17
Release date:2008-01-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
3BOH
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BU of 3boh by Molmil
Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 with acetate (CDCA1-R1)
Descriptor: ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase
Authors:Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M.
Deposit date:2007-12-17
Release date:2008-01-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
2NYM
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BU of 2nym by Molmil
Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit
Descriptor: MANGANESE (II) ION, Protein phosphatase 2, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ...
Authors:Chen, Y, Xing, Y, Xu, Y, Chao, Y, Lin, Z, Jeffrey, P.D, Shi, Y.
Deposit date:2006-11-21
Release date:2006-12-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure of the Protein Phosphatase 2A Holoenzyme.
Cell(Cambridge,Mass.), 127, 2006

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數據於2024-07-17公開中

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