6PE7
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![BU of 6pe7 by Molmil](/molmil-images/mine/6pe7) | Crystal Structure of ABBV-323 FAB | Descriptor: | FAB Heavy Chain, FAB Light chain, SULFATE ION | Authors: | Argiriadi, M.A. | Deposit date: | 2019-06-20 | Release date: | 2019-08-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches. BMC Mol Cell Biol, 20, 2019
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4XXB
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![BU of 4xxb by Molmil](/molmil-images/mine/4xxb) | Crystal structure of human MDM2-RPL11 | Descriptor: | 60S ribosomal protein L11, BETA-MERCAPTOETHANOL, E3 ubiquitin-protein ligase Mdm2, ... | Authors: | Zheng, J, Chen, Z. | Deposit date: | 2015-01-30 | Release date: | 2015-08-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation Genes Dev., 29, 2015
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6PE9
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![BU of 6pe9 by Molmil](/molmil-images/mine/6pe9) | Crystal Structure of CD40 complexed to FAB516 | Descriptor: | FAB Heavy chain, FAB Light chain, SULFATE ION, ... | Authors: | Argiriadi, M.A. | Deposit date: | 2019-06-20 | Release date: | 2019-08-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.13 Å) | Cite: | CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches. BMC Mol Cell Biol, 20, 2019
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6ITY
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![BU of 6ity by Molmil](/molmil-images/mine/6ity) | CTX-M-64 sulbactam complex | Descriptor: | ACRYLIC ACID, Beta-lactamase, TRANS-ENAMINE INTERMEDIATE OF SULBACTAM | Authors: | Cheng, Q, Chen, S. | Deposit date: | 2018-11-26 | Release date: | 2019-10-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution. Acs Infect Dis., 6, 2020
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7KJS
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![BU of 7kjs by Molmil](/molmil-images/mine/7kjs) | Crystal structure of CDK2/cyclin E in complex with PF-06873600 | Descriptor: | 6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)piperidin-4-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 | Authors: | McTigue, M.A, He, Y, Ferre, R.A. | Deposit date: | 2020-10-26 | Release date: | 2021-06-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.187 Å) | Cite: | Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer. J.Med.Chem., 64, 2021
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6J2B
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![BU of 6j2b by Molmil](/molmil-images/mine/6j2b) | CTX-M-64 beta-lactamase S130T sulbactam complex | Descriptor: | Beta-lactamase, GLYCEROL, TRANS-ENAMINE INTERMEDIATE OF SULBACTAM | Authors: | Cheng, Q, Chen, S. | Deposit date: | 2018-12-31 | Release date: | 2019-10-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution. Acs Infect Dis., 6, 2020
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6PE8
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![BU of 6pe8 by Molmil](/molmil-images/mine/6pe8) | Crystal structure of CD40/ABBV-323 FAB complex | Descriptor: | FAB Heavy chain, FAB Light chain, SULFATE ION, ... | Authors: | Argiriadi, M.A. | Deposit date: | 2019-06-20 | Release date: | 2019-08-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches. BMC Mol Cell Biol, 20, 2019
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6J2O
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![BU of 6j2o by Molmil](/molmil-images/mine/6j2o) | Crystal structure of CTX-M-64 clavulanic acid complex | Descriptor: | (2E)-3-[(4-hydroxy-2-oxobutyl)amino]prop-2-enal, Beta-lactamase | Authors: | Cheng, Q, Chen, S. | Deposit date: | 2019-01-02 | Release date: | 2019-10-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution. Acs Infect Dis., 6, 2020
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6J25
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![BU of 6j25 by Molmil](/molmil-images/mine/6j25) | CTX-M-64 beta-lactamase mutant-S130T | Descriptor: | Beta-lactamase | Authors: | Cheng, Q, Chen, S. | Deposit date: | 2018-12-30 | Release date: | 2019-10-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution. Acs Infect Dis., 6, 2020
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5YZ3
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![BU of 5yz3 by Molmil](/molmil-images/mine/5yz3) | Crystal structure of T2R-TTL-28 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Yu, Y, Chen, Q. | Deposit date: | 2017-12-12 | Release date: | 2018-10-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.545 Å) | Cite: | A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors. Cancer Res., 78, 2018
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6J2K
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![BU of 6j2k by Molmil](/molmil-images/mine/6j2k) | CTX-M-64 beta-lactamase S130T clavulanic acid complex | Descriptor: | (2E)-3-[(4-hydroxy-2-oxobutyl)amino]prop-2-enal, Beta-lactamase | Authors: | Cheng, Q, Chen, S. | Deposit date: | 2019-01-01 | Release date: | 2019-10-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution. Acs Infect Dis., 6, 2020
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6C6K
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![BU of 6c6k by Molmil](/molmil-images/mine/6c6k) | Structural basis for preferential recognition of cap 0 RNA by a human IFIT1-IFIT3 protein complex | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 1, Interferon-induced protein with tetratricopeptide repeats 3, MAGNESIUM ION, ... | Authors: | Amarasinghe, G.K, Leung, D.W, Johnson, B, Xu, W. | Deposit date: | 2018-01-18 | Release date: | 2018-04-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability. Immunity, 48, 2018
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2PIY
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![BU of 2piy by Molmil](/molmil-images/mine/2piy) | |
7MFJ
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![BU of 7mfj by Molmil](/molmil-images/mine/7mfj) | Structural Characterization of Beta Cyanoalanine Synthase from Tetranychus Urticae | Descriptor: | ACETATE ION, Beta-cyanoalanine synthase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Daneshian, L, Schlachter, C, Dermauw, W, Wybouw, N, Van Leeuwen, T, Chruszcz, M. | Deposit date: | 2021-04-09 | Release date: | 2021-11-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.351 Å) | Cite: | Structural and functional characterization of beta-cyanoalanine synthase from Tetranychus urticae. Insect Biochem.Mol.Biol., 142, 2022
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5UF7
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![BU of 5uf7 by Molmil](/molmil-images/mine/5uf7) | CRYSTAL STRUCTURE OF MUNC13-1 MUN DOMAIN | Descriptor: | Protein unc-13 homolog A | Authors: | Tomchick, D.R, Rizo, J, Xu, J. | Deposit date: | 2017-01-03 | Release date: | 2017-02-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.896 Å) | Cite: | Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN. Elife, 6, 2017
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6UYE
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![BU of 6uye by Molmil](/molmil-images/mine/6uye) | EBOV GPdMuc Makona bound to rEBOV-548 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody rEBOV-548 Fab, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2019-11-13 | Release date: | 2020-03-11 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity, 52, 2020
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4WRU
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![BU of 4wru by Molmil](/molmil-images/mine/4wru) | Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with uracil, Form II | Descriptor: | CHLORIDE ION, GLYCEROL, URACIL, ... | Authors: | Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M. | Deposit date: | 2014-10-25 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications. Acta Crystallogr.,Sect.D, 71, 2015
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4WRW
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![BU of 4wrw by Molmil](/molmil-images/mine/4wrw) | Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase, Form IV | Descriptor: | CHLORIDE ION, GLYCEROL, Uracil-DNA glycosylase | Authors: | Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M. | Deposit date: | 2014-10-25 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications. Acta Crystallogr.,Sect.D, 71, 2015
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4WRY
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![BU of 4wry by Molmil](/molmil-images/mine/4wry) | Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 5-fluorouracil(B), Form I | Descriptor: | 5-FLUOROURACIL, CHLORIDE ION, CITRIC ACID, ... | Authors: | Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M. | Deposit date: | 2014-10-25 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications. Acta Crystallogr.,Sect.D, 71, 2015
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4WS1
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![BU of 4ws1 by Molmil](/molmil-images/mine/4ws1) | Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 5-fluorouracil (AB), Form II | Descriptor: | 1,2-ETHANEDIOL, 5-FLUOROURACIL, CHLORIDE ION, ... | Authors: | Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M. | Deposit date: | 2014-10-25 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications. Acta Crystallogr.,Sect.D, 71, 2015
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4WS5
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![BU of 4ws5 by Molmil](/molmil-images/mine/4ws5) | Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 5-nitrouracil, Form III | Descriptor: | 5-nitrouracil, CHLORIDE ION, Uracil-DNA glycosylase | Authors: | Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M. | Deposit date: | 2014-10-25 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications. Acta Crystallogr.,Sect.D, 71, 2015
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6W2L
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![BU of 6w2l by Molmil](/molmil-images/mine/6w2l) | Crystal structure of human dehydrodolichyl diphosphate synthase (NgBR/DHDDS) in complex with Mg and IPP | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, ... | Authors: | Edani, B.H, Ha, Y, Sessa, W.C. | Deposit date: | 2020-03-06 | Release date: | 2020-08-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.306 Å) | Cite: | Structural elucidation of thecis-prenyltransferase NgBR/DHDDS complex reveals insights in regulation of protein glycosylation. Proc.Natl.Acad.Sci.USA, 117, 2020
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4WPK
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![BU of 4wpk by Molmil](/molmil-images/mine/4wpk) | Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase, Form I | Descriptor: | CITRIC ACID, SODIUM ION, Uracil-DNA glycosylase | Authors: | Arif, S.M, Geethanandan, K, Mishra, P, Surolia, A, Varshney, U, Vijayan, M. | Deposit date: | 2014-10-20 | Release date: | 2015-07-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications. Acta Crystallogr.,Sect.D, 71, 2015
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7D89
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![BU of 7d89 by Molmil](/molmil-images/mine/7d89) | |
5T4Z
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![BU of 5t4z by Molmil](/molmil-images/mine/5t4z) | |