5WY0

Crystal structure of the methyltranferase domain of human HEN1 in complex with AdoMet

Summary for 5WY0

• Entry DOI: 10.2210/pdb5wy0/pdb
• Descriptor: Small RNA 2'-O-methyltransferase, S-ADENOSYLMETHIONINE (3 entities in total)
• Functional Keywords: rna methyltranferase, adomet, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 26520.98

Authors

Peng, L.,Ma, J.B.,Wu, L.G.,Huang, Y. (deposition date: 2017-01-10, release date: 2018-01-17, Last modification date: 2024-03-20)

• Primary citation: Peng, L.,Zhang, F.,Shang, R.,Wang, X.,Chen, J.,Chou, J.J.,Ma, J.,Wu, L.,Huang, Y.; Identification of substrates of the small RNA methyltransferase Hen1 in mouse spermatogonial stem cells and analysis of its methyl-transfer domain; J. Biol. Chem., 293:9981-9994, 2018; PubMed: 29703750; DOI: 10.1074/jbc.RA117.000837

Experimental method

X-RAY DIFFRACTION (2.001 Å)