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5WY0

Crystal structure of the methyltranferase domain of human HEN1 in complex with AdoMet

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Small RNA 2'-O-methyltransferasepolymer23026122.51UniProt (Q5T8I9)
Pfam (PF13489)
Homo sapiens (Human)HEN1 methyltransferase homolog 1
2B
(A)
S-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
3C
(A)
waterwater18.0115Chemie (HOH)
Sequence modifications
A: 1 - 228 (UniProt: Q5T8I9)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight26122.5
Non-Polymers*Number of molecules1
Total formula weight398.4
All*Total formula weight26521.0
*Water molecules are not included.

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PDB entries from 2025-12-17

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