4QG3
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![BU of 4qg3 by Molmil](/molmil-images/mine/4qg3) | Crystal structure of mutant ribosomal protein G219V TthL1 in complex with 80nt 23S RNA from Thermus thermophilus | Descriptor: | 50S ribosomal protein L1, BETA-MERCAPTOETHANOL, ISOPROPYL ALCOHOL, ... | Authors: | Gabdulkhakov, A.G, Nevskaya, N.A, Nikonov, S.V. | Deposit date: | 2014-05-22 | Release date: | 2015-02-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions. Acta Crystallogr.,Sect.D, 71, 2015
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4QVI
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![BU of 4qvi by Molmil](/molmil-images/mine/4qvi) | Crystal structure of mutant ribosomal protein M218L TthL1 in complex with 80nt 23S RNA from Thermus thermophilus | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 50S ribosomal protein L1, ACETATE ION, ... | Authors: | Gabdulkhakov, A.G, Nevskaya, N.A, NIkonov, S.V. | Deposit date: | 2014-07-15 | Release date: | 2015-02-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions. Acta Crystallogr.,Sect.D, 71, 2015
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4IL2
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![BU of 4il2 by Molmil](/molmil-images/mine/4il2) | Crystal structure of D-mannonate dehydratase (rspA) from E. coli CFT073 (EFI TARGET EFI-501585) | Descriptor: | MAGNESIUM ION, Starvation sensing protein rspA | Authors: | Lukk, T, Wichelecki, D, Imker, H.J, Gerlt, J.A, Nair, S.K. | Deposit date: | 2012-12-28 | Release date: | 2013-02-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Mannonate degradation pathway in E. coli CFT073 To be Published
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4ILK
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![BU of 4ilk by Molmil](/molmil-images/mine/4ilk) | Crystal structure of short chain alcohol dehydrogenase (rspB) from E. coli CFT073 (EFI TARGET EFI-506413) complexed with cofactor NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MANGANESE (II) ION, Starvation sensing protein rspB, ... | Authors: | Lukk, T, Wichelecki, D, Imker, H.J, Gerlt, J.A, Nair, S.K. | Deposit date: | 2012-12-31 | Release date: | 2013-01-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Crystal structure of short chain alcohol dehydrogenase (rspB) from E. coli CFT073 (EFI TARGET EFI-506413) complexed with cofactor NADH To be Published
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4IM7
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![BU of 4im7 by Molmil](/molmil-images/mine/4im7) | Crystal structure of fructuronate reductase (ydfI) from E. coli CFT073 (EFI TARGET EFI-506389) complexed with NADH and D-mannonate | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, D-MANNONIC ACID, Hypothetical oxidoreductase ydfI, ... | Authors: | Lukk, T, Wichelecki, D, Imker, H.J, Gerlt, J.A, Nair, S.K. | Deposit date: | 2013-01-02 | Release date: | 2013-01-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of fructuronate reductase (ydfI) from E. coli CFT073 (EFI TARGET EFI-506389) complexed with NADH and D-mannonate To be Published
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3U4M
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![BU of 3u4m by Molmil](/molmil-images/mine/3u4m) | Crystal structure of ribosomal protein tthl1 in complex with 80nt 23s rna from thermus thermophilus | Descriptor: | 50S ribosomal protein L1, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Gabdulkhakov, A.G, Nevskaya, N.A, NIkonov, S.V. | Deposit date: | 2011-10-10 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | High-resolution crystal structure of the isolated ribosomal L1 stalk. Acta Crystallogr.,Sect.D, 68, 2012
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5V2N
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![BU of 5v2n by Molmil](/molmil-images/mine/5v2n) | Crystal Structure of APO Human SETD8 | Descriptor: | 1,2-ETHANEDIOL, N-lysine methyltransferase KMT5A | Authors: | Skene, R.J. | Deposit date: | 2017-03-05 | Release date: | 2018-03-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The dynamic conformational landscape of the protein methyltransferase SETD8. Elife, 8, 2019
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7FHJ
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![BU of 7fhj by Molmil](/molmil-images/mine/7fhj) | Crystal structure of BAZ2A with DNA | Descriptor: | Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*CP*GP*GP*AP*AP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*TP*TP*CP*CP*G)-3'), ... | Authors: | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | Deposit date: | 2021-07-29 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status. J.Biol.Chem., 297, 2021
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3UVQ
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![BU of 3uvq by Molmil](/molmil-images/mine/3uvq) | Human p38 MAP Kinase in Complex with a Dibenzosuberone Derivative | Descriptor: | Mitogen-activated protein kinase 14, N-{5-[(7-{[(2R)-2,3-dihydroxypropyl]oxy}-5-oxo-10,11-dihydro-5H-dibenzo[a,d][7]annulen-2-yl)amino]-2-fluorophenyl}benzamide, octyl beta-D-glucopyranoside | Authors: | Mayer-Wrangowski, S.C, Richters, A, Gruetter, C, Rauh, D. | Deposit date: | 2011-11-30 | Release date: | 2012-12-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Dibenzosuberones as p38 mitogen-activated protein kinase inhibitors with low ATP competitiveness and outstanding whole blood activity. J.Med.Chem., 56, 2013
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1F5T
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![BU of 1f5t by Molmil](/molmil-images/mine/1f5t) | DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL AND DTXR CONSENSUS BINDING SEQUENCE | Descriptor: | 43MER DNA CONTAINING DXTR CONSENSUS BINDING SEQUENCE, DIPHTHERIA TOXIN REPRESSOR, NICKEL (II) ION | Authors: | Chen, S, White, A, Love, J, Murphy, J.R, Ringe, D. | Deposit date: | 2000-06-15 | Release date: | 2000-09-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Methyl groups of thymine bases are important for nucleic acid recognition by DtxR. Biochemistry, 39, 2000
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2EZK
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![BU of 2ezk by Molmil](/molmil-images/mine/2ezk) | SOLUTION NMR STRUCTURE OF THE IBETA SUBDOMAIN OF THE MU END DNA BINDING DOMAIN OF PHAGE MU TRANSPOSASE, REGULARIZED MEAN STRUCTURE | Descriptor: | TRANSPOSASE | Authors: | Clore, G.M, Clubb, R.T, Schumaker, S, Gronenborn, A.M. | Deposit date: | 1997-10-04 | Release date: | 1998-01-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the Mu end DNA-binding ibeta subdomain of phage Mu transposase: modular DNA recognition by two tethered domains. EMBO J., 16, 1997
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2EZL
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![BU of 2ezl by Molmil](/molmil-images/mine/2ezl) | SOLUTION NMR STRUCTURE OF THE IBETA SUBDOMAIN OF THE MU END DNA BINDING DOMAIN OF PHAGE MU TRANSPOSASE, 29 STRUCTURES | Descriptor: | TRANSPOSASE | Authors: | Clore, G.M, Clubb, R.T, Schumaker, S, Gronenborn, A.M. | Deposit date: | 1997-10-04 | Release date: | 1998-01-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the Mu end DNA-binding ibeta subdomain of phage Mu transposase: modular DNA recognition by two tethered domains. EMBO J., 16, 1997
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2ZCH
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![BU of 2zch by Molmil](/molmil-images/mine/2zch) | Crystal structure of human prostate specific antigen complexed with an activating antibody | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, CHLORIDE ION, PHOSPHATE ION, ... | Authors: | Menez, R, Stura, E, Jolivet-Reynaud, C. | Deposit date: | 2007-11-08 | Release date: | 2008-01-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody J.Mol.Biol., 376, 2008
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2ZCL
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![BU of 2zcl by Molmil](/molmil-images/mine/2zcl) | Crystal structure of human prostate specific antigen complexed with an activating antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Prostate-specific antigen, monoclonal antibody 8G8F5 Fab | Authors: | Menez, R, Stura, E, Jolivet-Reynaud, C. | Deposit date: | 2007-11-09 | Release date: | 2008-01-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody J.Mol.Biol., 376, 2008
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2ZCK
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![BU of 2zck by Molmil](/molmil-images/mine/2zck) | Crystal structure of a ternary complex between PSA, a substrat-acyl intermediate and an activating antibody | Descriptor: | KGISSQY, Prostate-specific antigen, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Menez, R, Stura, E, Jolivet-Reynaud, C. | Deposit date: | 2007-11-09 | Release date: | 2008-01-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody J.Mol.Biol., 376, 2008
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2XGP
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![BU of 2xgp by Molmil](/molmil-images/mine/2xgp) | Yeast DNA polymerase eta in complex with C8-2-acetylaminofluorene containing DNA | Descriptor: | 5'-D(*CP*8FG*CP*TP*CP*AP*TP*CP*CP*AP*C)-3', 5'-D(*GP*TP*GP*GP*AP*TP*GP*AP*G)-3', CALCIUM ION, ... | Authors: | Scheider, S, Lammens, K, Schorr, S, Hopfner, K.P, Carell, T. | Deposit date: | 2010-06-07 | Release date: | 2010-11-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Mechanism of Replication Blocking and Bypass of Y-Family Polymerase Eta by Bulky Acetylaminofluorene DNA Adducts. Proc.Natl.Acad.Sci.USA, 107, 2010
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3TG8
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![BU of 3tg8 by Molmil](/molmil-images/mine/3tg8) | Mutant ribosomal protein L1 lacking ala158 from thermus thermophilus | Descriptor: | 50S ribosomal protein L1, CHLORIDE ION, TETRAETHYLENE GLYCOL | Authors: | Gabdulkhakov, A.G, Nevskaya, N.A, Nikonov, S.V. | Deposit date: | 2011-08-17 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural analysis of interdomain mobility in ribosomal L1 proteins. Acta Crystallogr.,Sect.D, 67, 2011
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2PSU
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![BU of 2psu by Molmil](/molmil-images/mine/2psu) | Crystal Structure of wild type HIV-1 protease in complex with CARB-AD37 | Descriptor: | ACETATE ION, N-[(1S,2R)-1-BENZYL-3-{(CYCLOPROPYLMETHYL)[(3-METHOXYPHENYL)SULFONYL]AMINO}-2-HYDROXYPROPYL]-N'-METHYLSUCCINAMIDE, PHOSPHATE ION, ... | Authors: | Schiffer, C.A, Nalam, M.N.L. | Deposit date: | 2007-05-07 | Release date: | 2007-06-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Design of Mutation-resistant HIV Protease Inhibitors with the Substrate Envelope Hypothesis. Chem.Biol.Drug Des., 69, 2007
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4NIW
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![BU of 4niw by Molmil](/molmil-images/mine/4niw) | |
4NIV
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![BU of 4niv by Molmil](/molmil-images/mine/4niv) | |
2PSV
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![BU of 2psv by Molmil](/molmil-images/mine/2psv) | |
4NIY
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![BU of 4niy by Molmil](/molmil-images/mine/4niy) | Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) complexed to YRH-ecotin (M84Y/M85R/A86H ecotin) | Descriptor: | CALCIUM ION, Cationic trypsin, Ecotin, ... | Authors: | Schoepfel, M, Parthier, C, Stubbs, M.T. | Deposit date: | 2013-11-08 | Release date: | 2014-02-19 | Last modified: | 2014-03-19 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | N-terminal protein modification by substrate-activated reverse proteolysis. Angew.Chem.Int.Ed.Engl., 53, 2014
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4NIX
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![BU of 4nix by Molmil](/molmil-images/mine/4nix) | Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) orthorhombic form, zinc-bound | Descriptor: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | Authors: | Schoepfel, M, Parthier, C, Stubbs, M.T. | Deposit date: | 2013-11-08 | Release date: | 2014-02-19 | Last modified: | 2014-03-19 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | N-terminal protein modification by substrate-activated reverse proteolysis. Angew.Chem.Int.Ed.Engl., 53, 2014
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8J72
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![BU of 8j72 by Molmil](/molmil-images/mine/8j72) | Crystal structure of mammalian Trim71 in complex with lncRNA Trincr1 | Descriptor: | E3 ubiquitin-protein ligase TRIM71, lncRNA Trincr1 | Authors: | Shi, F.D, Zhang, K, Che, S.Y, Zhi, S.X, Yang, N. | Deposit date: | 2023-04-27 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | Molecular mechanism governing RNA-binding property of mammalian TRIM71 protein. Sci Bull (Beijing), 69, 2024
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9C0Y
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![BU of 9c0y by Molmil](/molmil-images/mine/9c0y) | Clathrin terminal domain complexed with Pitstop 2c | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Clathrin heavy chain 1, ... | Authors: | Bulut, H, Horatscheck, A, Krauss, M, Santos, K.F, McCluskey, A, Wahl, C.W, Nazare, M, Haucke, V. | Deposit date: | 2024-05-28 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Acute inhibition of clathrin-mediated endocytosis by next-generation small molecule inhibitors of clathrin function To Be Published
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