2PSU

Crystal Structure of wild type HIV-1 protease in complex with CARB-AD37

Summary for 2PSU

• Entry DOI: 10.2210/pdb2psu/pdb
• Related: 2psv
• Descriptor: Protease, PHOSPHATE ION, ACETATE ION, ... (5 entities in total)
• Functional Keywords: drug design, hiv-1 protease, protease inhibitor, hydrolase
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 2
• Total formula weight: 22647.19

Authors

Schiffer, C.A.,Nalam, M.N.L. (deposition date: 2007-05-07, release date: 2007-06-05, Last modification date: 2023-08-30)

• Primary citation: Chellappan, S.,Kiran Kumar Reddy, G.S.,Ali, A.,Nalam, M.N.,Anjum, S.G.,Cao, H.,Kairys, V.,Fernandes, M.X.,Altman, M.D.,Tidor, B.,Rana, T.M.,Schiffer, C.A.,Gilson, M.K.; Design of Mutation-resistant HIV Protease Inhibitors with the Substrate Envelope Hypothesis.; Chem.Biol.Drug Des., 69:298-313, 2007; PubMed: 17539822; DOI: 10.1111/j.1747-0285.2007.00514.x

Experimental method

X-RAY DIFFRACTION (1.93 Å)