3U4M
Crystal structure of ribosomal protein tthl1 in complex with 80nt 23s rna from thermus thermophilus
Summary for 3U4M
| Entry DOI | 10.2210/pdb3u4m/pdb |
| Related | 1MZP 1U63 1ZHO 2HW8 2VPL 3U42 |
| Descriptor | 50S ribosomal protein L1, RNA (80-MER), SULFATE ION, ... (8 entities in total) |
| Functional Keywords | rossmann fold, ribosomal protein, rrna, rrna binding, ribosome, rna-rna binding protein complex, rna/rna binding protein |
| Biological source | Thermus thermophilus More |
| Total number of polymer chains | 2 |
| Total formula weight | 52056.00 |
| Authors | Gabdulkhakov, A.G.,Nevskaya, N.A.,NIkonov, S.V. (deposition date: 2011-10-10, release date: 2012-08-08, Last modification date: 2023-09-13) |
| Primary citation | Tishchenko, S.,Gabdulkhakov, A.,Nevskaya, N.,Sarskikh, A.,Kostareva, O.,Nikonova, E.,Sycheva, A.,Moshkovskii, S.,Garber, M.,Nikonov, S. High-resolution crystal structure of the isolated ribosomal L1 stalk. Acta Crystallogr.,Sect.D, 68:1051-1057, 2012 Cited by PubMed Abstract: The crystal structure of the isolated full-length ribosomal L1 stalk, consisting of Thermus thermophilus ribosomal protein L1 in complex with a specific 80-nucleotide fragment of 23S rRNA, has been solved for the first time at high resolution. The structure revealed details of protein-RNA interactions in the L1 stalk. Analysis of the crystal packing enabled the identification of sticky sites on the protein and the 23S rRNA which may be important for ribosome assembly and function. The structure was used to model different conformational states of the ribosome. This approach provides an insight into the roles of domain II of L1 and helix 78 of rRNA in ribosome function. PubMed: 22868771DOI: 10.1107/S0907444912020136 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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