5WPT
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![BU of 5wpt by Molmil](/molmil-images/mine/5wpt) | Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed II conformation at 3.75 Angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION | Authors: | Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. | Deposit date: | 2017-08-07 | Release date: | 2017-10-18 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structure of mammalian endolysosomal TRPML1 channel in nanodiscs. Nature, 550, 2017
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6BCL
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![BU of 6bcl by Molmil](/molmil-images/mine/6bcl) | cryo-EM structure of TRPM4 in apo state with long coiled coil at 3.5 angstrom resolution | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily M member 4 | Authors: | Guo, J, She, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2017-10-20 | Release date: | 2017-12-13 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structures of the calcium-activated, non-selective cation channel TRPM4. Nature, 552, 2017
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6BCJ
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![BU of 6bcj by Molmil](/molmil-images/mine/6bcj) | cryo-EM structure of TRPM4 in apo state with short coiled coil at 3.1 angstrom resolution | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily M member 4 | Authors: | Guo, J, She, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2017-10-20 | Release date: | 2017-12-13 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Structures of the calcium-activated, non-selective cation channel TRPM4. Nature, 552, 2017
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6BCQ
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![BU of 6bcq by Molmil](/molmil-images/mine/6bcq) | cryo-EM structure of TRPM4 in ATP bound state with long coiled coil at 3.3 angstrom resolution | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Transient receptor potential cation channel subfamily M member 4 | Authors: | Guo, J, She, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2017-10-20 | Release date: | 2017-12-13 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structures of the calcium-activated, non-selective cation channel TRPM4. Nature, 552, 2017
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6BCO
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![BU of 6bco by Molmil](/molmil-images/mine/6bco) | cryo-EM structure of TRPM4 in ATP bound state with short coiled coil at 2.9 angstrom resolution | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Transient receptor potential cation channel subfamily M member 4 | Authors: | Guo, J, She, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2017-10-20 | Release date: | 2017-12-13 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structures of the calcium-activated, non-selective cation channel TRPM4. Nature, 552, 2017
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8HVT
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![BU of 8hvt by Molmil](/molmil-images/mine/8hvt) | Structure of the human CLC-7/Ostm1 complex reveals a novel state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H(+)/Cl(-) exchange transporter 7, Osteopetrosis-associated transmembrane protein 1, ... | Authors: | Zhang, Z.X, Chen, L, He, J, She, J. | Deposit date: | 2022-12-27 | Release date: | 2024-01-03 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the human CLC-7/Ostm1 complex reveals a novel state JUSTC, 53, 2023
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5WPQ
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![BU of 5wpq by Molmil](/molmil-images/mine/5wpq) | Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed I conformation at 3.64 Angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION | Authors: | Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. | Deposit date: | 2017-08-07 | Release date: | 2017-10-18 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Structure of mammalian endolysosomal TRPML1 channel in nanodiscs. Nature, 550, 2017
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5WPV
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![BU of 5wpv by Molmil](/molmil-images/mine/5wpv) | Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs at 3.59 Angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION | Authors: | Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y. | Deposit date: | 2017-08-07 | Release date: | 2017-10-18 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Structure of mammalian endolysosomal TRPML1 channel in nanodiscs. Nature, 550, 2017
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5WTT
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![BU of 5wtt by Molmil](/molmil-images/mine/5wtt) | Structure of the 093G9 Fab in complex with the epitope peptide | Descriptor: | Epitope peptide of Cyr61, Heavy chain of 093G9 Fab, Light chain of 093G9 Fab | Authors: | Zhong, C, Hu, K, Shen, J, Ding, J. | Deposit date: | 2016-12-14 | Release date: | 2017-12-20 | Last modified: | 2019-01-02 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular basis for the recognition of CCN1 by monoclonal antibody 093G9. J. Mol. Recognit., 30, 2017
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7S4A
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![BU of 7s4a by Molmil](/molmil-images/mine/7s4a) | MRG15 complex with PALB2 peptide | Descriptor: | Mortality factor 4-like protein 1, Partner and localizer of BRCA2 | Authors: | Korolev, S, Deveryshetty, J. | Deposit date: | 2021-09-08 | Release date: | 2022-05-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.693 Å) | Cite: | Structural Insight into the Mechanism of PALB2 Interaction with MRG15. Genes (Basel), 12, 2021
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1MZH
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![BU of 1mzh by Molmil](/molmil-images/mine/1mzh) | QR15, an Aldolase | Descriptor: | Deoxyribose-phosphate aldolase, PHOSPHATE ION | Authors: | Tan, A.Y, Smith, P.C, Shen, J, Xiao, R, Acton, T, Rost, B, Montelione, G, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-10-07 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Aquifex Aeolicus Aldolase,
Northeast Structural Genomics Consortium Target
QR15 To be Published
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1MW7
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![BU of 1mw7 by Molmil](/molmil-images/mine/1mw7) | X-RAY STRUCTURE OF Y162_HELPY NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET PR6 | Descriptor: | HYPOTHETICAL PROTEIN HP0162 | Authors: | Kuzin, A, Shen, J, Keller, J.P, Xiao, R, Rost, B, Montelione, G, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-09-27 | Release date: | 2003-01-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-RAY STRUCTURE OF Y162_HELPY NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET PR6 To be published
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8C5U
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![BU of 8c5u by Molmil](/molmil-images/mine/8c5u) | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 8-mer RNA, pppGpGpUpApApApUpG (IC8) | Descriptor: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | Deposit date: | 2023-01-10 | Release date: | 2023-08-30 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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8C5S
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![BU of 8c5s by Molmil](/molmil-images/mine/8c5s) | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 7-mer RNA, pppGpGpUpApApApU (IC7) | Descriptor: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | Deposit date: | 2023-01-10 | Release date: | 2023-08-30 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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7D32
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![BU of 7d32 by Molmil](/molmil-images/mine/7d32) | The TBA-Pb2+ complex in P41212 space group | Descriptor: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | Authors: | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | Deposit date: | 2020-09-18 | Release date: | 2021-09-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.707 Å) | Cite: | Structure-guided development of Pb 2+ -binding DNA aptamers. Sci Rep, 12, 2022
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7D31
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![BU of 7d31 by Molmil](/molmil-images/mine/7d31) | The TBA-Pb2+ complex in P41212 space group | Descriptor: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | Authors: | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | Deposit date: | 2020-09-18 | Release date: | 2021-09-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.396 Å) | Cite: | Structure-guided development of Pb 2+ -binding DNA aptamers. Sci Rep, 12, 2022
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7D33
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![BU of 7d33 by Molmil](/molmil-images/mine/7d33) | The Pb2+ complexed structure of TBA G8C mutant | Descriptor: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*CP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | Authors: | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | Deposit date: | 2020-09-18 | Release date: | 2021-09-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.117 Å) | Cite: | Structure-guided development of Pb 2+ -binding DNA aptamers. Sci Rep, 12, 2022
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6LT0
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![BU of 6lt0 by Molmil](/molmil-images/mine/6lt0) | cryo-EM structure of C9ORF72-SMCR8-WDR41 | Descriptor: | Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8, WD repeat-containing protein 41 | Authors: | Tang, D, Sheng, J, Xu, L, Zhan, X, Yan, C, Qi, S. | Deposit date: | 2020-01-21 | Release date: | 2020-04-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a. Proc.Natl.Acad.Sci.USA, 117, 2020
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5HN2
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![BU of 5hn2 by Molmil](/molmil-images/mine/5hn2) | |
5HNJ
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![BU of 5hnj by Molmil](/molmil-images/mine/5hnj) | |
8EF5
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![BU of 8ef5 by Molmil](/molmil-images/mine/8ef5) | Fentanyl-bound mu-opioid receptor-Gi complex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | Deposit date: | 2022-09-08 | Release date: | 2022-11-09 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor. Cell, 185, 2022
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8EF6
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![BU of 8ef6 by Molmil](/molmil-images/mine/8ef6) | Morphine-bound mu-opioid receptor-Gi complex | Descriptor: | (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | Deposit date: | 2022-09-08 | Release date: | 2022-11-09 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor. Cell, 185, 2022
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8EFL
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![BU of 8efl by Molmil](/molmil-images/mine/8efl) | SR17018-bound mu-opioid receptor-Gi complex | Descriptor: | 5,6-dichloro-1-{1-[(4-chlorophenyl)methyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | Deposit date: | 2022-09-08 | Release date: | 2022-11-09 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor. Cell, 185, 2022
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8EFO
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![BU of 8efo by Molmil](/molmil-images/mine/8efo) | PZM21-bound mu-opioid receptor-Gi complex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | Deposit date: | 2022-09-08 | Release date: | 2022-11-09 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor. Cell, 185, 2022
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8EFB
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![BU of 8efb by Molmil](/molmil-images/mine/8efb) | Oliceridine-bound mu-opioid receptor-Gi complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | Deposit date: | 2022-09-08 | Release date: | 2022-11-09 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor. Cell, 185, 2022
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