7F8N
| Human pannexin-1 showing a conformational change in the N-terminal domain and blocked pore | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | Authors: | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2021-07-02 | Release date: | 2022-01-26 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci.Signal., 15, 2022
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7F8J
| Cryo-EM structure of human pannexin-1 in a nanodisc | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | Authors: | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2021-07-02 | Release date: | 2022-01-26 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci.Signal., 15, 2022
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7F8O
| Cryo-EM structure of the C-terminal deletion mutant of human PANX1 in a nanodisc | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | Authors: | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2021-07-02 | Release date: | 2022-01-26 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci.Signal., 15, 2022
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6KFG
| Undocked INX-6 hemichannel in detergent | Descriptor: | Innexin-6 | Authors: | Burendei, B, Shinozaki, R, Watanabe, M, Terada, T, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2019-07-07 | Release date: | 2020-02-12 | Last modified: | 2020-03-11 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids. Sci Adv, 6, 2020
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6KFF
| Undocked INX-6 hemichannel in a nanodisc | Descriptor: | Innexin-6 | Authors: | Burendei, B, Shinozaki, R, Watanabe, M, Terada, T, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2019-07-07 | Release date: | 2020-02-12 | Last modified: | 2020-03-11 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids. Sci Adv, 6, 2020
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6KFH
| Undocked hemichannel of an N-terminal deletion mutant of INX-6 in a nanodisc | Descriptor: | Innexin-6 | Authors: | Burendei, B, Shinozaki, R, Watanabe, M, Terada, T, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2019-07-07 | Release date: | 2020-02-12 | Last modified: | 2020-03-11 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids. Sci Adv, 6, 2020
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5YLV
| Crystal structure of the gastric proton pump complexed with SCH28080 | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(2-methyl-8-phenylmethoxy-imidazo[1,2-a]pyridin-3-yl)ethanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | Deposit date: | 2017-10-19 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.79977775 Å) | Cite: | Crystal structures of the gastric proton pump Nature, 556, 2018
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5Y0B
| PIG GASTRIC H+,K+ - ATPASE IN COMPLEX with BYK99 | Descriptor: | Potassium-transporting ATPase alpha chain 1, Potassium-transporting ATPase subunit beta | Authors: | Abe, K, Shimokawa, J, Natio, M, Munson, K, Vagin, O, Sachs, G, Suzuki, H, Tani, K, Fujiyoshi, Y. | Deposit date: | 2017-07-16 | Release date: | 2017-08-09 | Method: | ELECTRON CRYSTALLOGRAPHY (6.7 Å) | Cite: | The cryo-EM structure of gastric H(+),K(+)-ATPase with bound BYK99, a high-affinity member of K(+)-competitive, imidazo[1,2-a]pyridine inhibitors Sci Rep, 7, 2017
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5YLU
| Crystal structure of the gastric proton pump complexed with vonoprazan | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonyl-pyrrol-3-yl]-~{N}-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | Deposit date: | 2017-10-19 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.79988956 Å) | Cite: | Crystal structures of the gastric proton pump Nature, 556, 2018
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6ACF
| structure of leucine dehydrogenase from Geobacillus stearothermophilus by cryo-EM | Descriptor: | Leucine dehydrogenase | Authors: | Yamaguchi, H, Kamegawa, A, Nakata, K, Kashiwagi, T, Mizukoshi, T, Fujiyoshi, Y, Tani, K. | Deposit date: | 2018-07-26 | Release date: | 2018-12-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into thermostabilization of leucine dehydrogenase from its atomic structure by cryo-electron microscopy J. Struct. Biol., 205, 2019
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6LKN
| Crystal structure of ATP11C-CDC50A in PtdSer-bound E2P state | Descriptor: | 1-deoxy-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, ... | Authors: | Abe, K, Irie, K, Nakanishi, H, Hasegawa, K. | Deposit date: | 2019-12-19 | Release date: | 2020-06-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Crystal structure of a human plasma membrane phospholipid flippase. J.Biol.Chem., 295, 2020
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2H8A
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8H9X
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8H9Y
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8HA1
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8HA2
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7BSS
| Cryo-EM structure of a human ATP11C-CDC50A flippase in E1AlF state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP11C, CDC50A, ... | Authors: | Abe, K, Nishizawa, T, Nakanishi, H. | Deposit date: | 2020-03-31 | Release date: | 2020-09-30 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Rep, 32, 2020
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7BSQ
| Cryo-EM structure of a human ATP11C-CDC50A flippase in E1AlF-ADP state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ATP11C, ... | Authors: | Abe, K, Nishizawa, T, Nakanishi, H. | Deposit date: | 2020-03-31 | Release date: | 2020-09-30 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Rep, 32, 2020
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7BSU
| Cryo-EM structure of a human ATP11C-CDC50A flippase in PtdSer-bound E2BeF state | Descriptor: | 1-deoxy-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP11C, ... | Authors: | Abe, K, Nishizawa, T, Nakanishi, H. | Deposit date: | 2020-03-31 | Release date: | 2020-09-30 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Rep, 32, 2020
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7BSP
| Cryo-EM structure of a human ATP11C-CDC50A flippase in E1-AMPPCP state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP11C, ... | Authors: | Abe, K, Nishizawa, T, Nakanishi, H. | Deposit date: | 2020-03-31 | Release date: | 2020-09-30 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Rep, 32, 2020
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7BSV
| Cryo-EM structure of a human ATP11C-CDC50A flippase in PtdSer-occluded E2-AlF state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP11C, CDC50A, ... | Authors: | Abe, K, Nishizawa, T, Nakanishi, H. | Deposit date: | 2020-03-31 | Release date: | 2020-09-30 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Rep, 32, 2020
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7BSW
| Cryo-EM structure of a human ATP11C-CDC50A flippase in PtdEtn-occluded E2-AlF state | Descriptor: | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP11C, ... | Authors: | Abe, K, Nishizawa, T, Nakanishi, H. | Deposit date: | 2020-03-31 | Release date: | 2020-09-30 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Rep, 32, 2020
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8H9O
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8H9W
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1H6I
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