6LKN

Crystal structure of ATP11C-CDC50A in PtdSer-bound E2P state

Summary for 6LKN

• Entry DOI: 10.2210/pdb6lkn/pdb
• Descriptor: Phospholipid-transporting ATPase IG, Cell cycle control protein 50A, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ... (7 entities in total)
• Functional Keywords: p-type atpase, flippase, apoptosis, phosphatidylserine, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 692042.96

Authors

Abe, K.,Irie, K.,Nakanishi, H.,Hasegawa, K. (deposition date: 2019-12-19, release date: 2020-06-10, Last modification date: 2023-11-22)

• Primary citation: Nakanishi, H.,Irie, K.,Segawa, K.,Hasegawa, K.,Fujiyoshi, Y.,Nagata, S.,Abe, K.; Crystal structure of a human plasma membrane phospholipid flippase.; J.Biol.Chem., 295:10180-10194, 2020; PubMed: 32493773; DOI: 10.1074/jbc.RA120.014144

Experimental method

X-RAY DIFFRACTION (3.9 Å)