6LKN
Crystal structure of ATP11C-CDC50A in PtdSer-bound E2P state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E, I, M | Phospholipid-transporting ATPase IG | polymer | 1129 | 129710.6 | 4 | UniProt (Q8NB49) Pfam (PF16209) Pfam (PF00122) Pfam (PF13246) Pfam (PF16212) In PDB | Homo sapiens (Human) | ATPase IQ,ATPase class VI type 11C,P4-ATPase flippase complex alpha subunit ATP11C |
2 | C, F, J, N | Cell cycle control protein 50A | polymer | 361 | 40840.7 | 4 | UniProt (Q9NV96) Pfam (PF03381) In PDB | Homo sapiens (Human) | P4-ATPase flippase complex beta subunit TMEM30A,Transmembrane protein 30A |
3 | M, A, C, E, I | O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | non-polymer | 792.1 | 7 | Chemie (P5S) | |||
4 | I, M, A, E | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
5 | J, N, C, F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) | |||
6 | J, N, C, F | 1-deoxy-alpha-D-mannopyranose | non-polymer | 164.2 | 4 | Chemie (AH2) | |||
7 | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, E, I, M: 10 - 1129 (UniProt: Q8NB49)
C, F, J, N: 1 - 361 (UniProt: Q9NV96)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Phe 2 | - | expression tag |
Arg 3 | - | expression tag |
Arg 4 | - | expression tag |
Ser 5 | - | expression tag |
Leu 6 | - | expression tag |
Asn 7 | - | expression tag |
Arg 8 | - | expression tag |
Phe 9 | - | expression tag |
Trp 111 | Cys 114 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gln 190 | Asn 190 | engineered mutation |
Trp 292 | Ser 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 682205.3 | |
Non-Polymers* | Number of molecules | 31 |
Total formula weight | 9837.7 | |
All* | Total formula weight | 692043.0 |