1E8A
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![BU of 1e8a by Molmil](/molmil-images/mine/1e8a) | The three-dimensional structure of human S100A12 | Descriptor: | CALCIUM ION, S100A12 | Authors: | Moroz, O.V, Antson, A.A, Murshudov, G.N, Maitland, N.J, Dodson, G.G, Wilson, K.S, Skibshoj, I, Lukanidin, E.M, Bronstein, I.B. | Deposit date: | 2000-09-18 | Release date: | 2001-01-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Three-Dimensional Structure of Human S100A12 Acta Crystallogr.,Sect.D, 57, 2001
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1GK9
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![BU of 1gk9 by Molmil](/molmil-images/mine/1gk9) | Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, PENICILLIN G ACYLASE ALPHA SUBUNIT, ... | Authors: | McVey, C.E, Walsh, M.A, Dodson, G.G, Wilson, K.S, Brannigan, J.A. | Deposit date: | 2001-08-10 | Release date: | 2002-01-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal Structures of Penicillin Acylase Enzyme-Substrate Complexes: Structural Insights Into the Catalytic Mechanism J.Mol.Biol., 313, 2001
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1GOY
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![BU of 1goy by Molmil](/molmil-images/mine/1goy) | HYDROLASE(ENDORIBONUCLEASE)RIBONUCLEASE BI(G SPECIFIC ENDONUCLEASE) (E.C.3.1.27.-) COMPLEXED WITH GUANOSINE-3'-PHOSPHATE (3'-GMP) | Descriptor: | GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE, SULFATE ION | Authors: | Polyakov, K.M, Lebedev, A.A, Pavlovsky, A.G, Sanishvili, R.G, Dodson, G.G. | Deposit date: | 2001-10-26 | Release date: | 2001-11-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Structure of Substrate-Free Microbial Ribonuclease Binase and of its Complexes with 3'Gmp and Sulfate Ions Acta Crystallogr.,Sect.D, 58, 2002
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1GOV
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![BU of 1gov by Molmil](/molmil-images/mine/1gov) | RIBONUCLEASE BI(G SPECIFIC ENDONUCLEASE) COMPLEXED WITH SULFATE IONS | Descriptor: | RIBONUCLEASE, SULFATE ION | Authors: | Polyakov, K.M, Lebedev, A.A, Pavlovsky, A.G, Sanishvili, R.G, Dodson, G.G. | Deposit date: | 2001-10-26 | Release date: | 2001-11-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Structure of Substrate-Free Microbial Ribonuclease Binase and of its Complexes with 3'Gmp and Sulfate Ions Acta Crystallogr.,Sect.D, 58, 2002
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1QIZ
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![BU of 1qiz by Molmil](/molmil-images/mine/1qiz) | HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR COMPLEXED WITH RESORCINOL | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | Authors: | Tang, L, Whittingham, J.L, Verma, C.S, Caves, L.S.D, Dodson, G.G. | Deposit date: | 1999-06-18 | Release date: | 1999-06-22 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis. Biochemistry, 38, 1999
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1QJ0
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![BU of 1qj0 by Molmil](/molmil-images/mine/1qj0) | HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | Authors: | Tang, L, Whittingham, J.L, Verma, C.S, Caves, L.S.D, Dodson, G.G. | Deposit date: | 1999-06-18 | Release date: | 1999-06-22 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis. Biochemistry, 38, 1999
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1QIY
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![BU of 1qiy by Molmil](/molmil-images/mine/1qiy) | HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR COMPLEXED WITH PHENOL | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | Authors: | Tang, L, Whittingham, J.L, Verma, C.S, Caves, L.S.D, Dodson, G.G. | Deposit date: | 1999-06-18 | Release date: | 1999-06-22 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis. Biochemistry, 38, 1999
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2WS7
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![BU of 2ws7 by Molmil](/molmil-images/mine/2ws7) | Semi-synthetic analogue of human insulin ProB26-DTI | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | Deposit date: | 2009-09-03 | Release date: | 2010-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
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2WS1
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![BU of 2ws1 by Molmil](/molmil-images/mine/2ws1) | Semi-synthetic analogue of human insulin NMeTyrB26-insulin in monomer form | Descriptor: | ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | Deposit date: | 2009-09-03 | Release date: | 2010-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
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2WRV
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![BU of 2wrv by Molmil](/molmil-images/mine/2wrv) | Semi-synthetic highly active analogue of human insulin NMeHisB26-DTI- NH2 | Descriptor: | ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | Deposit date: | 2009-09-02 | Release date: | 2010-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
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2WRW
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![BU of 2wrw by Molmil](/molmil-images/mine/2wrw) | Semi-synthetic highly active analogue of human insulin D-ProB26-DTI- NH2 | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | Deposit date: | 2009-09-02 | Release date: | 2010-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
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2WS6
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![BU of 2ws6 by Molmil](/molmil-images/mine/2ws6) | Semi-synthetic analogue of human insulin NMeTyrB26-insulin in hexamer form | Descriptor: | CHLORIDE ION, GLYCEROL, INSULIN A CHAIN, ... | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | Deposit date: | 2009-09-03 | Release date: | 2010-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
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2WRX
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![BU of 2wrx by Molmil](/molmil-images/mine/2wrx) | Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0 | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN, SODIUM ION | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | Deposit date: | 2009-09-02 | Release date: | 2010-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
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2WRU
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![BU of 2wru by Molmil](/molmil-images/mine/2wru) | Semi-synthetic highly active analogue of human insulin NMeAlaB26-DTI- NH2 | Descriptor: | ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | Deposit date: | 2009-09-02 | Release date: | 2010-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
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2WS4
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![BU of 2ws4 by Molmil](/molmil-images/mine/2ws4) | Semi-synthetic analogue of human insulin ProB26-DTI in monomer form | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | Deposit date: | 2009-09-03 | Release date: | 2010-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
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2WS0
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![BU of 2ws0 by Molmil](/molmil-images/mine/2ws0) | Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5 | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | Deposit date: | 2009-09-03 | Release date: | 2010-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
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1EYV
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![BU of 1eyv by Molmil](/molmil-images/mine/1eyv) | THE CRYSTAL STRUCTURE OF NUSB FROM MYCOBACTERIUM TUBERCULOSIS | Descriptor: | N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG, PHOSPHATE ION | Authors: | Gopal, B, Haire, L.F, Cox, R.A, Colston, M.J, Major, S, Brannigan, J.A, Smerdon, S.J, Dodson, G.G, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2000-05-09 | Release date: | 2000-05-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structure of NusB from Mycobacterium tuberculosis. Nat.Struct.Biol., 7, 2000
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1GWF
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![BU of 1gwf by Molmil](/molmil-images/mine/1gwf) | Compound II structure of Micrococcus Lysodeikticus catalase | Descriptor: | ACETATE ION, Catalase, OXYGEN ATOM, ... | Authors: | Murshudov, G.N, Grebenko, A.I, Brannigan, J.A, Antson, A.A, Barynin, V.V, Dodson, G.G, Dauter, Z, Wilson, K.S, Melik-Adamyan, W.R. | Deposit date: | 2002-03-15 | Release date: | 2002-04-26 | Last modified: | 2018-06-20 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | The Structures of Micrococcus Lysodeikticus Catalase, its Ferryl Intermediate (Compound II) and Nadph Complex. Acta Crystallogr.,Sect.D, 58, 2002
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1GWE
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![BU of 1gwe by Molmil](/molmil-images/mine/1gwe) | Atomic resolution structure of Micrococcus Lysodeikticus catalase | Descriptor: | Catalase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Murshudov, G.N, Grebenko, A.I, Brannigan, J.A, Antson, A.A, Barynin, V.V, Dodson, G.G, Dauter, Z, Wilson, K.S, Melik-Adamyan, W.R. | Deposit date: | 2002-03-15 | Release date: | 2002-04-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (0.88 Å) | Cite: | The Structures of Micrococcus Lysodeikticus Catalase, its Ferryl Intermediate (Compound II) and Nadph Complex. Acta Crystallogr.,Sect.D, 58, 2002
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1H8I
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![BU of 1h8i by Molmil](/molmil-images/mine/1h8i) | X-ray crystal structure of human alpha-thrombin with a tripeptide phosphonate inhibitor. | Descriptor: | HIRUDIN I, N-[(benzyloxy)carbonyl]-beta-phenyl-D-phenylalanyl-N-[(1S)-4-methoxy-1-phosphonobutyl]-L-prolinamide, THROMBIN | Authors: | Skordalakes, E, Dodson, G.G, Green, D, Deadman, J. | Deposit date: | 2001-02-08 | Release date: | 2001-03-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Inhibition of Human Alpha-Thrombin by a Phosphonate Tripeptide Proceeds Via a Metastable Pentacoordinated Phosphorus Intermediate J.Mol.Biol., 311, 2001
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1GWH
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![BU of 1gwh by Molmil](/molmil-images/mine/1gwh) | Atomic resolution structure of Micrococcus Lysodeikticus catalase complexed with NADPH | Descriptor: | ACETATE ION, Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Murshudov, G.N, Grebenko, A.I, Brannigan, J.A, Antson, A.A, Barynin, V.V, Dodson, G.G, Dauter, Z, Wilson, K.S, Melik-Adamyan, W.R. | Deposit date: | 2002-03-15 | Release date: | 2002-03-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | The Structures of Micrococcus Lysodeikticus Catalase, its Ferryl Intermediate (Compound II) and Nadph Complex. Acta Crystallogr.,Sect.D, 58, 2002
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1GOU
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![BU of 1gou by Molmil](/molmil-images/mine/1gou) | |
1H8D
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![BU of 1h8d by Molmil](/molmil-images/mine/1h8d) | X-ray structure of the human alpha-thrombin complex with a tripeptide phosphonate inhibitor. | Descriptor: | HIRUDIN I, N-[(benzyloxy)carbonyl]-beta-phenyl-D-phenylalanyl-N-{(1S,3E)-1-[dihydroxy(diphenoxy)-lambda~5~-phosphanyl]-4-methoxybut-3-en-1-yl}-L-prolinamide, THROMBIN | Authors: | Skordalakes, E, Dodson, G.G, Green, D, Deadman, J. | Deposit date: | 2001-02-01 | Release date: | 2001-02-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Inhibition of Human Alpha-Thrombin by a Phosphonate Tripeptide Proceeds Via a Metastable Pentacoordinated Phosphorus Intermediate J.Mol.Biol., 311, 2001
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1GUJ
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![BU of 1guj by Molmil](/molmil-images/mine/1guj) | Insulin at pH 2: structural analysis of the conditions promoting insulin fibre formation. | Descriptor: | INSULIN, SULFATE ION | Authors: | Whittingham, J.L, Scott, D.J, Chance, K, Wilson, A, Finch, J, Brange, J, Dodson, G.G. | Deposit date: | 2002-01-28 | Release date: | 2002-03-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Insulin at Ph2: Structural Analysis of the Conditions Promoting Insulin Fibre Formation J.Mol.Biol., 318, 2002
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1AX4
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![BU of 1ax4 by Molmil](/molmil-images/mine/1ax4) | TRYPTOPHANASE FROM PROTEUS VULGARIS | Descriptor: | POTASSIUM ION, TRYPTOPHANASE | Authors: | Isupov, M.N, Antson, A.A, Dodson, E.J, Dodson, G.G, Dementieva, I.S, Zakomirdina, L.N, Wilson, K.S, Dauter, Z, Lebedev, A.A, Harutyunyan, E.H. | Deposit date: | 1997-10-28 | Release date: | 1998-01-28 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of tryptophanase. J.Mol.Biol., 276, 1998
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