3WE4
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3WF6
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![BU of 3wf6 by Molmil](/molmil-images/mine/3wf6) | Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]-1H-pyrazolo[3,4-d]pyrimidine | Descriptor: | 4-[4-(1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]-1H-pyrazolo[3,4-d]pyrimidine, Ribosomal protein S6 kinase beta-1, ZINC ION | Authors: | Niwa, H, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-07-17 | Release date: | 2014-08-06 | Last modified: | 2014-10-29 | Method: | X-RAY DIFFRACTION (2.031 Å) | Cite: | Crystal structures of the S6K1 kinase domain in complexes with inhibitors J.Struct.Funct.Genom., 15, 2014
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2DVQ
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![BU of 2dvq by Molmil](/molmil-images/mine/2dvq) | Crystal structure analysis of the N-terminal bromodomain of human BRD2 complexed with acetylated histone H4 peptide | Descriptor: | Bromodomain-containing protein 2, histone H4 | Authors: | Nakamura, Y, Umehara, T, Shirouzu, M, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-08-01 | Release date: | 2007-08-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain. J.Biol.Chem., 285, 2010
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2DVR
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![BU of 2dvr by Molmil](/molmil-images/mine/2dvr) | Crystal structure analysis of the N-terminal bromodomain of human BRD2 complexed with acetylated histone H4 peptide | Descriptor: | bromodomain-containing protein 2, histone H4 | Authors: | Nakamura, Y, Umehara, T, Shirouzu, M, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-08-01 | Release date: | 2007-08-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain. J.Biol.Chem., 285, 2010
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3WF7
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![BU of 3wf7 by Molmil](/molmil-images/mine/3wf7) | Crystal structure of S6K1 kinase domain in complex with a purine derivative 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide | Descriptor: | 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide, GLYCEROL, Ribosomal protein S6 kinase beta-1, ... | Authors: | Niwa, H, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-07-17 | Release date: | 2014-08-06 | Last modified: | 2014-10-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structures of the S6K1 kinase domain in complexes with inhibitors J.Struct.Funct.Genom., 15, 2014
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3WF5
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![BU of 3wf5 by Molmil](/molmil-images/mine/3wf5) | Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine | Descriptor: | 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine, Ribosomal protein S6 kinase beta-1, ZINC ION | Authors: | Niwa, H, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-07-17 | Release date: | 2014-08-06 | Last modified: | 2014-10-29 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | Crystal structures of the S6K1 kinase domain in complexes with inhibitors J.Struct.Funct.Genom., 15, 2014
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3WF8
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![BU of 3wf8 by Molmil](/molmil-images/mine/3wf8) | Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate | Descriptor: | 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate, GLYCEROL, Ribosomal protein S6 kinase beta-1, ... | Authors: | Niwa, H, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-07-17 | Release date: | 2014-08-06 | Last modified: | 2014-10-29 | Method: | X-RAY DIFFRACTION (1.975 Å) | Cite: | Crystal structures of the S6K1 kinase domain in complexes with inhibitors J.Struct.Funct.Genom., 15, 2014
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7FBR
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3WF9
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![BU of 3wf9 by Molmil](/molmil-images/mine/3wf9) | Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl-2-methyl-1,2,3,4-tetrahydroacridine-9-carboxylate | Descriptor: | (2S)-1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl (2S)-2-methyl-1,2,3,4-tetrahydroacridine-9-carboxylate, GLYCEROL, Ribosomal protein S6 kinase beta-1, ... | Authors: | Niwa, H, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-07-17 | Release date: | 2014-08-06 | Last modified: | 2014-10-29 | Method: | X-RAY DIFFRACTION (2.035 Å) | Cite: | Crystal structures of the S6K1 kinase domain in complexes with inhibitors J.Struct.Funct.Genom., 15, 2014
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6TJO
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![BU of 6tjo by Molmil](/molmil-images/mine/6tjo) | Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration | Descriptor: | Microtubule-associated protein tau | Authors: | Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W. | Deposit date: | 2019-11-26 | Release date: | 2020-02-05 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Novel tau filament fold in corticobasal degeneration. Nature, 580, 2020
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6TJX
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![BU of 6tjx by Molmil](/molmil-images/mine/6tjx) | Cryo-EM structure of TypeII tau filaments extracted from the brains of individuals with Corticobasal degeneration | Descriptor: | Microtubule-associated protein tau | Authors: | Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W. | Deposit date: | 2019-11-27 | Release date: | 2020-02-05 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Novel tau filament fold in corticobasal degeneration. Nature, 580, 2020
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5ZA1
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![BU of 5za1 by Molmil](/molmil-images/mine/5za1) | Ligand complex of RORgt LBD | Descriptor: | 1,2-ETHANEDIOL, 2-[4-({[4-(ethylsulfonyl)phenyl]acetyl}amino)phenyl]-2-methyl-N-phenylpropanamide, DIMETHYLFORMAMIDE, ... | Authors: | Yamamoto, S, Yamaguchi, H. | Deposit date: | 2018-02-06 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Discovery of a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (ROR gamma t) inhibitor, S18-000003. Bioorg. Med. Chem. Lett., 28, 2018
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2DZN
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2KUP
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![BU of 2kup by Molmil](/molmil-images/mine/2kup) | Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK | Descriptor: | 19-residue peptide from ALK tyrosine kinase receptor, Fibroblast growth factor receptor substrate 3 | Authors: | Li, H, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2010-02-24 | Release date: | 2010-05-26 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2 J.Struct.Funct.Genom., 11, 2010
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4GYD
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![BU of 4gyd by Molmil](/molmil-images/mine/4gyd) | Nostoc sp Cytochrome c6 | Descriptor: | Cytochrome c6, HEME C | Authors: | Skubak, P, Ubbink, M, Cavazzini, D, Rossi, G.L, Pannu, N.S. | Deposit date: | 2012-09-05 | Release date: | 2013-09-11 | Last modified: | 2019-10-02 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The dynamic complex of cytochrome c6 and cytochrome f studied with paramagnetic NMR spectroscopy Biochim.Biophys.Acta, 1837, 2014
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1NA1
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![BU of 1na1 by Molmil](/molmil-images/mine/1na1) | The structure of HRV14 when complexed with Pleconaril | Descriptor: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, Coat protein VP1, Coat protein VP2, ... | Authors: | Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. | Deposit date: | 2002-11-26 | Release date: | 2003-12-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds J.Virol., 78, 2004
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1AHI
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![BU of 1ahi by Molmil](/molmil-images/mine/1ahi) | 7 ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEXED WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 7 ALPHA-HYDROXYSTEROID DEHYDROGENASE, GLYCOCHENODEOXYCHOLIC ACID | Authors: | Tanaka, N, Nonaka, T, Mitsui, Y. | Deposit date: | 1995-08-25 | Release date: | 1996-10-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of the binary and ternary complexes of 7 alpha-hydroxysteroid dehydrogenase from Escherichia coli. Biochemistry, 35, 1996
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8UDG
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![BU of 8udg by Molmil](/molmil-images/mine/8udg) | S1V2-72 Fab bound to EHA2 from influenza B/Malaysia/2506/2004 | Descriptor: | Hemagglutinin, S1V2-72 heavy chain, S1V2-72 light chain | Authors: | Finney, J, Kong, S, Walsh Jr, R.M, Harrison, S.C, Kelsoe, G. | Deposit date: | 2023-09-28 | Release date: | 2023-11-15 | Last modified: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (4.98 Å) | Cite: | Protective human antibodies against a conserved epitope in pre- and postfusion influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FBV
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7WXX
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![BU of 7wxx by Molmil](/molmil-images/mine/7wxx) | Crystal structure of human MMP-7 in complex with inhibitor | Descriptor: | CALCIUM ION, Matrilysin, Peptide Inhibitor, ... | Authors: | Kamitani, M, Oka, Y, Tabuse, H. | Deposit date: | 2022-02-15 | Release date: | 2022-10-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Discovery of Highly Potent and Selective Matrix Metalloproteinase-7 Inhibitors by Hybridizing the S1' Subsite Binder with Short Peptides. J.Med.Chem., 65, 2022
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2DCQ
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2DX8
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1R9H
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2DT7
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![BU of 2dt7 by Molmil](/molmil-images/mine/2dt7) | Solution structure of the second SURP domain of human splicing factor SF3a120 in complex with a fragment of human splicing factor SF3a60 | Descriptor: | Splicing factor 3 subunit 1, Splicing factor 3A subunit 3 | Authors: | He, F, Kuwasako, K, Inoue, M, Guntert, P, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-07-11 | Release date: | 2006-12-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP Structure, 14, 2006
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2DVW
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