3FVX
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![BU of 3fvx by Molmil](/molmil-images/mine/3fvx) | Human kynurenine aminotransferase I in complex with tris | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Kynurenine--oxoglutarate transaminase 1, SODIUM ION | Authors: | Han, Q, Robinson, H, Cai, T, Tagle, D.A, Li, J. | Deposit date: | 2009-01-16 | Release date: | 2009-05-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K J.Med.Chem., 52, 2009
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1DUH
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![BU of 1duh by Molmil](/molmil-images/mine/1duh) | CRYSTAL STRUCTURE OF THE CONSERVED DOMAIN IV OF E. COLI 4.5S RNA | Descriptor: | 4.5S RNA DOMAIN IV, LUTETIUM (III) ION, MAGNESIUM ION, ... | Authors: | Jovine, L, Hainzl, T, Oubridge, C, Scott, W.G, Li, J, Sixma, T.K, Wonacott, A, Skarzynski, T, Nagai, K. | Deposit date: | 2000-01-17 | Release date: | 2000-05-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA. Structure Fold.Des., 8, 2000
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3EXE
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![BU of 3exe by Molmil](/molmil-images/mine/3exe) | Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex | Descriptor: | GLYCEROL, MANGANESE (II) ION, POTASSIUM ION, ... | Authors: | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T. | Deposit date: | 2008-10-16 | Release date: | 2008-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.979 Å) | Cite: | Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops. Structure, 16, 2008
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3EXH
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![BU of 3exh by Molmil](/molmil-images/mine/3exh) | Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex | Descriptor: | GLYCEROL, MANGANESE (II) ION, POTASSIUM ION, ... | Authors: | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T. | Deposit date: | 2008-10-16 | Release date: | 2008-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.444 Å) | Cite: | Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops. Structure, 16, 2008
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1OLU
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![BU of 1olu by Molmil](/molmil-images/mine/1olu) | Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase | Descriptor: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, GLYCEROL, ... | Authors: | Wynn, R.M, Machius, M, Chuang, J.L, Li, J, Tomchick, D.R, Chuang, D.T. | Deposit date: | 2003-08-15 | Release date: | 2003-08-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Roles of His291-Alpha and His146-Beta' in the Reductive Acylation Reaction Catalyzed by Human Branched-Chain Alpha-Ketoacid Dehydrogenase: Refined Phosphorylation Loop Structure in the Active Site. J.Biol.Chem., 278, 2003
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3UC4
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![BU of 3uc4 by Molmil](/molmil-images/mine/3uc4) | The crystal structure of Snf1-related kinase 2.6 | Descriptor: | Serine/threonine-protein kinase SRK2E | Authors: | Zhou, X.E, Ng, L.-M, Soon, F.-F, Kovach, A, Suino-Powell, K.M, Li, J, Melcher, K, Xu, H.E. | Deposit date: | 2011-10-26 | Release date: | 2011-12-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases. Proc.Natl.Acad.Sci.USA, 108, 2011
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5E8K
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![BU of 5e8k by Molmil](/molmil-images/mine/5e8k) | Crystal structure of polyprenyl pyrophosphate synthase 2 from Arabidopsis thaliana | Descriptor: | Geranylgeranyl pyrophosphate synthase 10, mitochondrial | Authors: | Wang, C, Chen, Q, Fan, D, Li, J, Wang, G, Zhang, P. | Deposit date: | 2015-10-14 | Release date: | 2015-11-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.028 Å) | Cite: | Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants. Mol Plant, 9, 2016
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7VQX
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![BU of 7vqx by Molmil](/molmil-images/mine/7vqx) | Cryo-EM structure of human vasoactive intestinal polypeptide receptor 2 (VIP2R) in complex with PACAP27 and Gs | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Xu, Y.N, Feng, W.B, Zhou, Q.T, Liang, A.Y, Li, J, Dai, A.T, Zhao, F.H, Yan, J.H, Chen, C.W, Li, H, Zhao, L.H, Xia, T, Jiang, Y, Xu, H.E, Yang, D.H, Wang, M.W. | Deposit date: | 2021-10-21 | Release date: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2. Nat Commun, 13, 2022
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7DQZ
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![BU of 7dqz by Molmil](/molmil-images/mine/7dqz) | Crystal structure of SARS 3C-like protease in apo form | Descriptor: | 3C-like proteinase | Authors: | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | Deposit date: | 2020-12-24 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
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5EZ6
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![BU of 5ez6 by Molmil](/molmil-images/mine/5ez6) | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | Authors: | Yan, Z, Ma, S, Zhang, Y, Ma, L, Wang, F, Li, J, Miao, L. | Deposit date: | 2015-11-26 | Release date: | 2016-12-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA To Be Published
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3KL4
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![BU of 3kl4 by Molmil](/molmil-images/mine/3kl4) | Recognition of a signal peptide by the signal recognition particle | Descriptor: | Signal peptide of yeast dipeptidyl aminopeptidase B, Signal recognition 54 kDa protein | Authors: | Janda, C.Y, Nagai, K, Li, J, Oubridge, C. | Deposit date: | 2009-11-06 | Release date: | 2010-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Recognition of a signal peptide by the signal recognition particle. Nature, 465, 2010
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8U8H
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![BU of 8u8h by Molmil](/molmil-images/mine/8u8h) | |
8U95
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![BU of 8u95 by Molmil](/molmil-images/mine/8u95) | The structure of myosin heavy chain from Drosophila melanogaster flight muscle thick filaments | Descriptor: | Myosin heavy chain, isoform U | Authors: | Abbasi Yeganeh, F, Rastegarpouyani, H, Li, J, Taylor, K.A. | Deposit date: | 2023-09-18 | Release date: | 2023-10-18 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structure of the Drosophila melanogaster Flight Muscle Myosin Filament at 4.7 angstrom Resolution Reveals New Details of Non-Myosin Proteins. Int J Mol Sci, 24, 2023
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7EO7
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![BU of 7eo7 by Molmil](/molmil-images/mine/7eo7) | Crystal structure of HCoV-NL63 3C-like protease in complex with an inhibitor Shikonin | Descriptor: | 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. | Deposit date: | 2021-04-21 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.24916625 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
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7EO8
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![BU of 7eo8 by Molmil](/molmil-images/mine/7eo8) | Crystal structure of SARS coronavirus main protease in complex with an inhibitor Shikonin | Descriptor: | 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase | Authors: | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | Deposit date: | 2021-04-21 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2808516 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
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3K40
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![BU of 3k40 by Molmil](/molmil-images/mine/3k40) | Crystal structure of Drosophila 3,4-dihydroxyphenylalanine decarboxylase | Descriptor: | Aromatic-L-amino-acid decarboxylase, GLYCEROL | Authors: | Han, Q, Ding, H, Robinson, H, Christensen, B.M, Li, J. | Deposit date: | 2009-10-05 | Release date: | 2010-02-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure and substrate specificity of Drosophila 3,4-dihydroxyphenylalanine decarboxylase Plos One, 5, 2010
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8I6O
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![BU of 8i6o by Molmil](/molmil-images/mine/8i6o) | |
8I6R
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![BU of 8i6r by Molmil](/molmil-images/mine/8i6r) | Cryo-EM structure of Pseudomonas aeruginosa FtsE(E163Q)X/EnvC complex with ATP in peptidisc | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | Authors: | Xu, X, Li, J, Luo, M. | Deposit date: | 2023-01-29 | Release date: | 2023-06-07 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site. Proc.Natl.Acad.Sci.USA, 120, 2023
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8I6S
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![BU of 8i6s by Molmil](/molmil-images/mine/8i6s) | Cryo-EM structure of Pseudomonas aeruginosa FtsE(E163Q)X/EnvC complex with ATP in peptidisc | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | Authors: | Xu, X, Li, J, Luo, M. | Deposit date: | 2023-01-29 | Release date: | 2023-06-07 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site. Proc.Natl.Acad.Sci.USA, 120, 2023
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3L3Z
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![BU of 3l3z by Molmil](/molmil-images/mine/3l3z) | Crystal structure of DHT-bound androgen receptor in complex with the third motif of steroid receptor coactivator 3 | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 3 | Authors: | Zhou, X.E, Suino-Powell, K.M, Li, J, He, A, MacKeigan, J.P, Melcher, K, Yong, E.-L, Xu, H.E. | Deposit date: | 2009-12-18 | Release date: | 2010-01-12 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor. J.Biol.Chem., 285, 2010
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4R8G
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![BU of 4r8g by Molmil](/molmil-images/mine/4r8g) | Crystal Structure of Myosin-1c tail in complex with Calmodulin | Descriptor: | Calmodulin, SULFATE ION, Unconventional myosin-Ic | Authors: | Lu, Q, Li, J, Ye, F, Zhang, M. | Deposit date: | 2014-09-02 | Release date: | 2014-12-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.503 Å) | Cite: | Structure of myosin-1c tail bound to calmodulin provides insights into calcium-mediated conformational coupling. Nat.Struct.Mol.Biol., 22, 2015
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3HLM
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![BU of 3hlm by Molmil](/molmil-images/mine/3hlm) | Crystal Structure of Mouse Mitochondrial Aspartate Aminotransferase/Kynurenine Aminotransferase IV | Descriptor: | Aspartate aminotransferase, mitochondrial, GLYCEROL | Authors: | Han, Q, Robinson, H, Li, J. | Deposit date: | 2009-05-27 | Release date: | 2010-06-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure, expression, and function of kynurenine aminotransferases in human and rodent brains. Cell.Mol.Life Sci., 67, 2010
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8WWS
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![BU of 8wws by Molmil](/molmil-images/mine/8wws) | Crystal structure of cis-epoxysuccinate hydrolase from Klebsiella oxytoca with L(+)-tartaric acid | Descriptor: | (S)-2-haloacid dehalogenase, 1,2-ETHANEDIOL, CARBONATE ION, ... | Authors: | Han, Y, Kong, X.D, Li, J, Xu, J.H. | Deposit date: | 2023-10-26 | Release date: | 2024-06-12 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural Insights of a cis -Epoxysuccinate Hydrolase Facilitate the Development of Robust Biocatalysts for the Production of l-(+)-Tartrate. Biochemistry, 63, 2024
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7WBJ
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![BU of 7wbj by Molmil](/molmil-images/mine/7wbj) | Cryo-EM structure of N-terminal modified human vasoactive intestinal polypeptide receptor 2 (VIP2R) in complex with PACAP27 and Gs | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Xu, Y.N, Feng, W.B, Zhou, Q.T, Liang, A.Y, Li, J, Dai, A.T, Zhao, F.H, Yan, J.H, Chen, C.W, Li, H, Zhao, L.H, Xia, T, Jiang, Y, Xu, H.E, Yang, D.H, Wang, M.W. | Deposit date: | 2021-12-16 | Release date: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2. Nat Commun, 13, 2022
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8XOY
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![BU of 8xoy by Molmil](/molmil-images/mine/8xoy) | The Crystal Structure of PTP1B from Biortus. | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Wang, F, Cheng, W, Lv, Z, Meng, Q, Li, J. | Deposit date: | 2024-01-02 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The Crystal Structure of PTP1B from Biortus. To Be Published
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