6JGX
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![BU of 6jgx by Molmil](/molmil-images/mine/6jgx) | Crystal structure of the transcriptional regulator CadR from P. putida in complex with Cadmium(II) and DNA | Descriptor: | CADMIUM ION, CadR, DNA (5'-D(*CP*AP*CP*CP*CP*TP*AP*TP*AP*GP*TP*GP*GP*CP*TP*AP*CP*AP*GP*GP*GP*T)-3'), ... | Authors: | Liu, X.C, Gan, J.H, Chen, H. | Deposit date: | 2019-02-15 | Release date: | 2019-09-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Selective cadmium regulation mediated by a cooperative binding mechanism in CadR. Proc.Natl.Acad.Sci.USA, 116, 2019
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7L5S
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![BU of 7l5s by Molmil](/molmil-images/mine/7l5s) | Crystal Structure of Haemophilus influenzae MtsZ at pH 5.5 | Descriptor: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, MOLYBDENUM ATOM, OXYGEN ATOM, ... | Authors: | Struwe, M.A, Luo, Z, Kappler, U, Kobe, B. | Deposit date: | 2020-12-22 | Release date: | 2021-04-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.089 Å) | Cite: | Active site architecture reveals coordination sphere flexibility and specificity determinants in a group of closely related molybdoenzymes. J.Biol.Chem., 296, 2021
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7L5I
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![BU of 7l5i by Molmil](/molmil-images/mine/7l5i) | Crystal Structure of Haemophilus influenzae MtsZ at pH 7.0 | Descriptor: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Struwe, M.A, Luo, Z, Kappler, U, Kobe, B. | Deposit date: | 2020-12-22 | Release date: | 2021-04-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.733 Å) | Cite: | Active site architecture reveals coordination sphere flexibility and specificity determinants in a group of closely related molybdoenzymes. J.Biol.Chem., 296, 2021
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6JGW
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7L4X
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7L4Y
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6JNI
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5UJT
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![BU of 5ujt by Molmil](/molmil-images/mine/5ujt) | Crystal structure of human HLA-DQ8 in complex with insulin mimotope binding in register 3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-beta-1, ... | Authors: | Wang, Y, Dai, S. | Deposit date: | 2017-01-18 | Release date: | 2017-12-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6KBD
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![BU of 6kbd by Molmil](/molmil-images/mine/6kbd) | fused To-MtbCsm1 with 2dATP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A),CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), MAGNESIUM ION | Authors: | Li, T, Huo, Y, Jiang, T. | Deposit date: | 2019-06-24 | Release date: | 2020-06-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mycobacterium tuberculosis CRISPR/Cas system Csm1 holds clues to the evolutionary relationship between DNA polymerase and cyclase activity. Int.J.Biol.Macromol., 170, 2020
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1DSS
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5Z9R
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6KOW
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4KYA
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![BU of 4kya by Molmil](/molmil-images/mine/4kya) | Crystal structure of non-classical TS inhibitor 3 in complex with Toxoplasma gondii TS-DHFR | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-Amino-5-(1-naphthylsulfanyl)-3,9-dihydro-4H-pyrimido[4,5-b]indol-4-one, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | Authors: | Sharma, H, Anderson, K.S. | Deposit date: | 2013-05-28 | Release date: | 2014-08-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.263 Å) | Cite: | Discovery of potent and selective inhibitors of Toxoplasma gondii thymidylate synthase for opportunistic infections. ACS Med Chem Lett, 4, 2013
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6NNG
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![BU of 6nng by Molmil](/molmil-images/mine/6nng) | Tubulin-RB3_SLD-TTL in complex with compound DJ95 | Descriptor: | 2-(1H-indol-6-yl)-4-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Kumar, G, Wang, Y, Li, W, White, S.W. | Deposit date: | 2019-01-15 | Release date: | 2019-07-10 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy. Mol.Pharmacol., 96, 2019
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5Z34
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1SZJ
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8IQC
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8IQI
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![BU of 8iqi by Molmil](/molmil-images/mine/8iqi) | Structure of Full-Length AsfvPrimPol in Complex-Form | Descriptor: | DNA (32-MER), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Shao, Z.W, Su, S.C, Gan, J.H. | Deposit date: | 2023-03-16 | Release date: | 2023-07-26 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Structures and implications of the C962R protein of African swine fever virus. Nucleic Acids Res., 51, 2023
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8IQH
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8IQD
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8IQB
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2N2K
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![BU of 2n2k by Molmil](/molmil-images/mine/2n2k) | Ensemble structure of the closed state of Lys63-linked diubiquitin in the absence of a ligand | Descriptor: | S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, ubiquitin | Authors: | Liu, Z, Gong, Z, Tang, C. | Deposit date: | 2015-05-10 | Release date: | 2015-07-08 | Last modified: | 2015-09-23 | Method: | SOLUTION NMR | Cite: | Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition. Elife, 4, 2015
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7SQK
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![BU of 7sqk by Molmil](/molmil-images/mine/7sqk) | Cryo-EM structure of the human augmin complex | Descriptor: | HAUS augmin-like complex subunit 1, HAUS augmin-like complex subunit 2, HAUS augmin-like complex subunit 3, ... | Authors: | Gabel, C.A, Chang, L. | Deposit date: | 2021-11-05 | Release date: | 2022-09-21 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Molecular architecture of the augmin complex. Nat Commun, 13, 2022
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2O8A
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![BU of 2o8a by Molmil](/molmil-images/mine/2o8a) | rat PP1cgamma complexed with mouse inhibitor-2 | Descriptor: | Protein phosphatase inhibitor 2, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | Authors: | Hurley, T.D. | Deposit date: | 2006-12-12 | Release date: | 2007-07-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural basis for regulation of protein phosphatase 1 by inhibitor-2. J.Biol.Chem., 282, 2007
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2O8G
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![BU of 2o8g by Molmil](/molmil-images/mine/2o8g) | Rat pp1c gamma complexed with mouse inhibitor-2 | Descriptor: | MANGANESE (II) ION, Protein phosphatase inhibitor 2, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | Authors: | Hurley, T.D. | Deposit date: | 2006-12-12 | Release date: | 2007-07-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for regulation of protein phosphatase 1 by inhibitor-2. J.Biol.Chem., 282, 2007
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