5H21
 
 | | Trimethoxy-ring inhibitor in complex with the first bromodomain of BRD4 | | Descriptor: | 3,4,5-trimethoxy-~{N}-(2-thiophen-2-ylethyl)benzamide, Bromodomain-containing protein 4 | | Authors: | Zhang, H, Luo, C. | | Deposit date: | 2016-10-13 | | Release date: | 2017-07-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.591 Å) | | Cite: | Discovery of novel trimethoxy-ring BRD4 bromodomain inhibitors: AlphaScreen assay, crystallography and cell-based assay.
Medchemcomm, 8, 2017
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1BMV
 | | PROTEIN-RNA INTERACTIONS IN AN ICOSAHEDRAL VIRUS AT 3.0 ANGSTROMS RESOLUTION | | Descriptor: | PROTEIN (ICOSAHEDRAL VIRUS - A DOMAIN), PROTEIN (ICOSAHEDRAL VIRUS - B AND C DOMAIN), RNA (5'-R(*GP*GP*UP*CP*AP*AP*AP*AP*UP*GP*C)-3') | | Authors: | Chen, Z, Stauffacher, C, Li, Y, Schmidt, T, Bomu, W, Kamer, G, Shanks, M, Lomonossoff, G, Johnson, J.E. | | Deposit date: | 1989-10-09 | | Release date: | 1989-10-09 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Protein-RNA interactions in an icosahedral virus at 3.0 A resolution.
Science, 245, 1989
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3NBJ
 | | Crystal Structure of Y305F mutant of the copper amine oxidase from Hansenula polymorpha expressed in yeast | | Descriptor: | COPPER (II) ION, PHOSPHATE ION, Peroxisomal primary amine oxidase | | Authors: | Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S. | | Deposit date: | 2010-06-03 | | Release date: | 2010-08-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
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3N9H
 | | Crystal Structural of mutant Y305A in the copper amine oxidase from hansenula polymorpha | | Descriptor: | COPPER (II) ION, Peroxisomal primary amine oxidase | | Authors: | Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S. | | Deposit date: | 2010-05-30 | | Release date: | 2010-08-25 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
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3NBB
 | | Crystal structure of mutant Y305F expressed in E. coli in the copper amine oxidase from hansenula polymorpha | | Descriptor: | COPPER (II) ION, Peroxisomal primary amine oxidase | | Authors: | Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S. | | Deposit date: | 2010-06-03 | | Release date: | 2010-08-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
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6WI5
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3DR9
 | | Increased Distal Histidine Conformational Flexibility in the Deoxy Form of Dehaloperoxidase from Amphitrite ornata | | Descriptor: | Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | Authors: | Chen, X, de Serrano, V.S, Betts, L, Franzen, S. | | Deposit date: | 2008-07-10 | | Release date: | 2009-01-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | Distal histidine conformational flexibility in dehaloperoxidase from Amphitrite ornata.
Acta Crystallogr.,Sect.D, 65, 2009
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6L5M
 | | Crystal structure of human DEAD-box RNA helicase DDX21 in complex with AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, Nucleolar RNA helicase 2 | | Authors: | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | | Deposit date: | 2019-10-24 | | Release date: | 2020-06-17 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
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6K9M
 | | Human LXR-beta in complex with an agonist | | Descriptor: | Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-propan-2-yl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate | | Authors: | Zhang, Z, Zhou, H. | | Deposit date: | 2019-06-16 | | Release date: | 2020-06-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Discovery of novel liver X receptor inverse agonists as lipogenesis inhibitors.
Eur.J.Med.Chem., 206, 2020
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3CMW
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3CMX
 | | Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DA)-3'), DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DT)-3'), ... | | Authors: | Pavletich, N.P. | | Deposit date: | 2008-03-24 | | Release date: | 2008-05-20 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
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3CMV
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3CMU
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7U9O
 | | SARS-CoV-2 spike trimer RBD in complex with Fab NE12 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NE12 Fab heavy chain, NE12 Fab light chain, ... | | Authors: | Tsybovsky, Y, Kwong, P.D, Farci, P. | | Deposit date: | 2022-03-11 | | Release date: | 2022-11-23 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
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7U9P
 | | SARS-CoV-2 spike trimer RBD in complex with Fab NA8 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NA8 Fab heavy chain, NA8 Fab light chain, ... | | Authors: | Tsybovsky, Y, Kwong, P.D, Farci, P. | | Deposit date: | 2022-03-11 | | Release date: | 2022-11-23 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
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6JZE
 | | Crystal structure of VASH2-SVBP complex with the magic triangle I3C | | Descriptor: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | | Authors: | Chen, Z, Ling, Y, Zeyuan, G, Zhu, L. | | Deposit date: | 2019-05-01 | | Release date: | 2019-08-07 | | Last modified: | 2023-04-05 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
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6JZD
 | | Crystal structure of peptide-bound VASH2-SVBP complex | | Descriptor: | GLU-GLY-GLU-GLU-TYR, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | | Authors: | Chen, Z, Ling, Y, Zeyuan, G, Zhu, L. | | Deposit date: | 2019-05-01 | | Release date: | 2019-07-17 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.479 Å) | | Cite: | Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
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6JZC
 | | Structural basis of tubulin detyrosination | | Descriptor: | GLYCEROL, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | | Authors: | Chen, Z, Ling, Y, Zeyuan, G, Zhu, L. | | Deposit date: | 2019-05-01 | | Release date: | 2019-07-17 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
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4QXH
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4QX7
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7CHJ
 | | crystal structure of pco4 | | Descriptor: | CITRIC ACID, FE (III) ION, Plant cysteine oxidase 4 | | Authors: | Guo, Q, Xu, C, Liao, S. | | Deposit date: | 2020-07-05 | | Release date: | 2020-11-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana.
J.Struct.Biol., 213, 2021
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7CHI
 | | crystal structure of pco5 | | Descriptor: | FE (III) ION, Plant cysteine oxidase 5 | | Authors: | Guo, Q, Xu, C, Liao, S. | | Deposit date: | 2020-07-05 | | Release date: | 2020-11-25 | | Last modified: | 2021-03-31 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana.
J.Struct.Biol., 213, 2021
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4QXC
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4QXB
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4QWN
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