6UZY
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![BU of 6uzy by Molmil](/molmil-images/mine/6uzy) | Cryo-EM structure of Xenopus tropicalis pannexin 1 | Descriptor: | HEXADECANE, Pannexin, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | Authors: | Deng, Z, He, Z, Yuan, P. | Deposit date: | 2019-11-15 | Release date: | 2020-04-01 | Last modified: | 2020-04-22 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Cryo-EM structures of the ATP release channel pannexin 1. Nat.Struct.Mol.Biol., 27, 2020
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5A6G
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![BU of 5a6g by Molmil](/molmil-images/mine/5a6g) | Cryo-EM structure of the Slo2.2 Na-activated K channel | Descriptor: | PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, S1-S4 DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 | Authors: | Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R. | Deposit date: | 2015-06-25 | Release date: | 2015-10-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel Nature, 527, 2015
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6V5A
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![BU of 6v5a by Molmil](/molmil-images/mine/6v5a) | Crystal structure of the human BK channel gating ring L390P mutant | Descriptor: | CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, SULFATE ION | Authors: | Deng, Z, Yuan, P. | Deposit date: | 2019-12-03 | Release date: | 2020-07-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Coupling of Ca2+and voltage activation in BK channels through the alpha B helix/voltage sensor interface. Proc.Natl.Acad.Sci.USA, 117, 2020
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6VXP
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6VXN
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![BU of 6vxn by Molmil](/molmil-images/mine/6vxn) | Cryo-EM structure of Arabidopsis thaliana MSL1 A320V | Descriptor: | DODECANE, Mechanosensitive ion channel protein 1, mitochondrial | Authors: | Deng, Z, Zhang, J, Yuan, P. | Deposit date: | 2020-02-22 | Release date: | 2020-08-05 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance. Nat Commun, 11, 2020
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6VXM
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![BU of 6vxm by Molmil](/molmil-images/mine/6vxm) | Cryo-EM structure of Arabidopsis thaliana MSL1 | Descriptor: | EICOSANE, Mechanosensitive ion channel protein 1, mitochondrial | Authors: | Deng, Z, Zhang, J, Yuan, P. | Deposit date: | 2020-02-22 | Release date: | 2020-08-05 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance. Nat Commun, 11, 2020
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5A6E
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![BU of 5a6e by Molmil](/molmil-images/mine/5a6e) | Cryo-EM structure of the Slo2.2 Na-activated K channel | Descriptor: | GATING RING OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, RCK2 ELABORATION OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, ... | Authors: | Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R. | Deposit date: | 2015-06-25 | Release date: | 2015-10-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel Nature, 527, 2015
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5A6F
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![BU of 5a6f by Molmil](/molmil-images/mine/5a6f) | Cryo-EM structure of the Slo2.2 Na-activated K channel | Descriptor: | GATING RING OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, RCK2 ELABORATION OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 | Authors: | Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R. | Deposit date: | 2015-06-25 | Release date: | 2015-10-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel Nature, 527, 2015
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5IT3
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![BU of 5it3 by Molmil](/molmil-images/mine/5it3) | Swirm domain of human Lsd1 | Descriptor: | Lysine-specific histone demethylase 1A, MAGNESIUM ION | Authors: | Jeffrey, P.D, Yuan, P. | Deposit date: | 2016-03-16 | Release date: | 2016-05-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | A Tlx-interacting peptide of Lsd1 inhibits the proliferation of brain tumor stem cells To Be Published
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8TDM
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![BU of 8tdm by Molmil](/molmil-images/mine/8tdm) | Cryo-EM structure of AtMSL10-K539E | Descriptor: | Mechanosensitive ion channel protein 10 | Authors: | Zhang, J, Yuan, P. | Deposit date: | 2023-07-03 | Release date: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Open structure and gating of the Arabidopsis mechanosensitive ion channel MSL10. Nat Commun, 14, 2023
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8TDJ
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8TDL
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8TDK
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![BU of 8tdk by Molmil](/molmil-images/mine/8tdk) | Cryo-EM structure of AtMSL10-G556V | Descriptor: | Mechanosensitive ion channel protein 10 | Authors: | Zhang, J, Yuan, P. | Deposit date: | 2023-07-03 | Release date: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Open structure and gating of the Arabidopsis mechanosensitive ion channel MSL10. Nat Commun, 14, 2023
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8T4Y
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![BU of 8t4y by Molmil](/molmil-images/mine/8t4y) | Human HCN1 F186C S264C C309A bound to cAMP, reconstituted in LMNG + SPL | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | Authors: | Burtscher, V, Mount, J, Cowgill, J, Chang, Y, Bickel, K, Yuan, P, Chanda, B. | Deposit date: | 2023-06-12 | Release date: | 2024-06-19 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Structural basis for hyperpolarization-dependent opening of human HCN1 channel. Nat Commun, 15, 2024
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8T50
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![BU of 8t50 by Molmil](/molmil-images/mine/8t50) | Open human HCN1 F186C S264C bound to cAMP, reconstituted in LMNG + SPL | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | Authors: | Burtscher, V, Mount, J, Cowgill, J, Chang, Y, Bickel, K, Yuan, P, Chanda, B. | Deposit date: | 2023-06-12 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for hyperpolarization-dependent opening of human HCN1 channel. Nat Commun, 15, 2024
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8T4M
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![BU of 8t4m by Molmil](/molmil-images/mine/8t4m) | Closed human HCN1 F186C S264C bound to cAMP, reconstituted in LMNG + SPL | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | Authors: | Burtscher, V, Mount, J, Cowgill, J, Chang, Y, Bickel, K, Yuan, P, Chanda, B. | Deposit date: | 2023-06-09 | Release date: | 2024-06-12 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structural basis for hyperpolarization-dependent opening of human HCN1 channel. Nat Commun, 15, 2024
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8TS2
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![BU of 8ts2 by Molmil](/molmil-images/mine/8ts2) | Cryo-EM structure of human MRS2 with EDTA | Descriptor: | Magnesium transporter MRS2 homolog, mitochondrial, Soluble cytochrome b562 fusion protein | Authors: | He, Z, Mount, J.W, Zhang, J, Yuan, P. | Deposit date: | 2023-08-10 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Human mitochondrial MRS2 is a Ca2+-regulated nonselective cation channel To Be Published
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8TS3
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![BU of 8ts3 by Molmil](/molmil-images/mine/8ts3) | Cryo-EM structure of human MRS2 with Ca2+ | Descriptor: | CALCIUM ION, Magnesium transporter MRS2 homolog, mitochondrial, ... | Authors: | He, Z, Mount, J.W, Zhang, J, Yuan, P. | Deposit date: | 2023-08-10 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Human mitochondrial MRS2 is a Ca2+-regulated nonselective cation channel To Be Published
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8TS1
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![BU of 8ts1 by Molmil](/molmil-images/mine/8ts1) | Cryo-EM structure of human MRS2 with Mg2+ | Descriptor: | MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial, ... | Authors: | He, Z, Mount, J.W, Zhang, J, Yuan, P. | Deposit date: | 2023-08-10 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Human mitochondrial MRS2 is a Ca2+-regulated nonselective cation channel To Be Published
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4KIS
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![BU of 4kis by Molmil](/molmil-images/mine/4kis) | Crystal Structure of a LSR-DNA Complex | Descriptor: | CALCIUM ION, DNA (26-MER), Putative integrase [Bacteriophage A118], ... | Authors: | Rutherford, K, Yuan, P, Perry, K, Van Duyne, G.D. | Deposit date: | 2013-05-02 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Attachment site recognition and regulation of directionality by the serine integrases. Nucleic Acids Res., 41, 2013
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3TSI
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![BU of 3tsi by Molmil](/molmil-images/mine/3tsi) | Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) stalk domain | Descriptor: | Hemagglutinin-neuraminidase | Authors: | Bose, S, Welch, B.D, Kors, C.A, Yuan, P, Jardetzky, T.S, Lamb, R.A. | Deposit date: | 2011-09-13 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.651 Å) | Cite: | Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion. J.Virol., 85, 2011
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6M84
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![BU of 6m84 by Molmil](/molmil-images/mine/6m84) | Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2 | Descriptor: | ATP-sensitive inward rectifier potassium channel 12, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ... | Authors: | Lee, S.-J, Ren, F, Yuan, P, Nichols, C.G. | Deposit date: | 2018-08-21 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels. J.Gen.Physiol., 152, 2020
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6M97
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![BU of 6m97 by Molmil](/molmil-images/mine/6m97) | Crystal structure of the high-affinity copper transporter Ctr1 | Descriptor: | Chimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562, HEXATANTALUM DODECABROMIDE, ZINC ION | Authors: | Ren, F, Yuan, P. | Deposit date: | 2018-08-22 | Release date: | 2019-04-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | X-ray structures of the high-affinity copper transporter Ctr1. Nat Commun, 10, 2019
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6M98
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6BBJ
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![BU of 6bbj by Molmil](/molmil-images/mine/6bbj) | Xenopus Tropicalis TRPV4 | Descriptor: | Transient receptor potential cation channel, subfamily V, member 4 | Authors: | Deng, Z, Hite, R.K, Yuan, P. | Deposit date: | 2017-10-18 | Release date: | 2018-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms. Nat. Struct. Mol. Biol., 25, 2018
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