7BUB
| Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 6.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dengue virus serotype 2 M protein, ... | Authors: | Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M. | Deposit date: | 2020-04-06 | Release date: | 2020-05-13 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep, 31, 2020
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7BUF
| Cryo-EM structure of Dengue virus serotype 2 complexed with SIgN-3C IgG | Descriptor: | Dengue virus serotype 2 E protein, Dengue virus serotype 2 M protein, SIgN-3C IgG heavy chain, ... | Authors: | Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M. | Deposit date: | 2020-04-06 | Release date: | 2020-05-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep, 31, 2020
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7CW3
| Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex) | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | Deposit date: | 2020-08-27 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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7CW0
| Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | Deposit date: | 2020-08-27 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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7C2S
| Helical reconstruction of Dengue virus serotype 3 complexed with Fab C10 | Descriptor: | Heavy chain of Fab C10, envelope protein, light chain of Fab C10 | Authors: | Morrone, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Zhang, S, Lok, S.M. | Deposit date: | 2020-05-09 | Release date: | 2020-07-08 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (10.4 Å) | Cite: | High flavivirus structural plasticity demonstrated by a non-spherical morphological variant. Nat Commun, 11, 2020
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7C2T
| Helical reconstruction of Zika virus complexed with Fab C10 | Descriptor: | Heavy chain from Fab C10, Light chain from Fab C10, M protein, ... | Authors: | Morrone, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Zhang, S, Lok, S.M. | Deposit date: | 2020-05-09 | Release date: | 2020-07-08 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | High flavivirus structural plasticity demonstrated by a non-spherical morphological variant. Nat Commun, 11, 2020
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3ZKO
| The structure of ''breathing'' dengue virus. | Descriptor: | ENVELOPE GLYCOPROTEIN | Authors: | Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Lee, S, Wang, J, Lok, S.M. | Deposit date: | 2013-01-24 | Release date: | 2013-05-15 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (13.7 Å) | Cite: | Structural Changes of Dengue Virus When Exposed to 37 Degrees C. J.Virol., 87, 2013
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7DWT
| Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 1 particle) | Descriptor: | Anti-dengue virus human monoclonal antibody 1C19 Fab heavy chain, Anti-dengue virus human monoclonal antibody 1C19 Fab light chain, envelope protein | Authors: | Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Shi, J, Lok, S.M. | Deposit date: | 2021-01-18 | Release date: | 2021-02-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (19 Å) | Cite: | Antibody affinity versus dengue morphology influences neutralization. Plos Pathog., 17, 2021
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7DWU
| Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 2 particle) | Descriptor: | Anti-dengue virus human monoclonal antibody 1C19 Fab heavy chain, Anti-dengue virus human monoclonal antibody 1C19 Fab light chain, envelope protein | Authors: | Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Shi, J, Lok, S.M. | Deposit date: | 2021-01-18 | Release date: | 2021-02-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (19 Å) | Cite: | Antibody affinity versus dengue morphology influences neutralization. Plos Pathog., 17, 2021
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3J31
| Life in the extremes: atomic structure of Sulfolobus Turreted Icosahedral Virus | Descriptor: | A223 penton base, A55 membrane protein, C381 turret protein, ... | Authors: | Veesler, D, Ng, T.S, Sendamarai, A.K, Eilers, B.J, Lawrence, C.M, Lok, S.M, Young, M.J, Johnson, J.E, Fu, C.-Y. | Deposit date: | 2013-02-18 | Release date: | 2013-05-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Atomic structure of the 75 MDa extremophile Sulfolobus turreted icosahedral virus determined by CryoEM and X-ray crystallography. Proc.Natl.Acad.Sci.USA, 110, 2013
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6LNU
| Cryo-EM structure of immature Zika virus | Descriptor: | Genome polyprotein | Authors: | Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M. | Deposit date: | 2020-01-02 | Release date: | 2020-02-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Capsid protein structure in Zika virus reveals the flavivirus assembly process. Nat Commun, 11, 2020
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6LNT
| Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab | Descriptor: | Envelope protein, Fab DV62.5 heavy-chain variable region, Fab DV62.5 light-chain variable region, ... | Authors: | Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M. | Deposit date: | 2020-01-02 | Release date: | 2020-02-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Capsid protein structure in Zika virus reveals the flavivirus assembly process. Nat Commun, 11, 2020
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4B03
| 6A Electron cryomicroscopy structure of immature Dengue virus serotype 1 | Descriptor: | DENGUE VIRUS 1 E PROTEIN, DENGUE VIRUS 1 PRM PROTEIN | Authors: | Kostyuchenko, V.A, Zhang, Q, Tan, L.C, Ng, T.S, Lok, S.M. | Deposit date: | 2012-06-28 | Release date: | 2013-06-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Immature and Mature Dengue Serotype 1 Virus Structures Provide Insight Into the Maturation Process. J.Virol., 87, 2013
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4CCT
| Dengue 1 cryo-EM reconstruction | Descriptor: | DENGUE VIRUS 1 E PROTEIN, DENGUE VIRUS 1 M PROTEIN | Authors: | Kostyuchenko, V.A, Zhang, Q, Tan, J.L, Ng, T.S, Lok, S.M. | Deposit date: | 2013-10-28 | Release date: | 2013-11-06 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Immature and Mature Dengue Serotype 1 Virus Structures Provide Insight Into the Maturation Process. J.Virol., 87, 2013
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4UIH
| Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation. | Descriptor: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN NEW GUINEA-C E PROTEIN ECTODOMAIN | Authors: | Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe, J.E, Lok, S.-M. | Deposit date: | 2015-03-30 | Release date: | 2015-07-15 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
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4UIF
| Cryo-EM structure of Dengue virus serotype 2 in complex with antigen-binding fragments of human antibody 2D22 | Descriptor: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN PVP94 07 - ENVELOPE PROTEIN, ... | Authors: | Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.-N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe Junior, J.E, Lok, S.-M. | Deposit date: | 2015-03-30 | Release date: | 2015-07-15 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
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7YAR
| ZIKV_Fab_G9E | Descriptor: | E protein, M protein, heavy chain, ... | Authors: | Shu, B, Thiam-Seng, N, Lok, S. | Deposit date: | 2022-06-28 | Release date: | 2023-01-04 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus. Plos Pathog., 19, 2023
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3J6T
| Cryo-EM structure of Dengue virus serotype 3 at 37 degrees C | Descriptor: | envelope protein, membrane protein | Authors: | Fibriansah, G, Tan, J.L, Smith, S.A, de Alwis, R, Ng, T.-S, Kostyuchenko, V.A, Kukkaro, P, de Silva, A.M, Crowe Jr, J.E, Lok, S.-M. | Deposit date: | 2014-03-25 | Release date: | 2015-03-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins. Nat Commun, 6, 2015
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3J6S
| Cryo-EM structure of Dengue virus serotype 3 at 28 degrees C | Descriptor: | envelope protein, membrane protein | Authors: | Fibriansah, G, Tan, J.L, Smith, S.A, de Alwis, R, Ng, T.-S, Kostyuchenko, V.A, Kukkaro, P, de Silva, A.M, Crowe Jr, J.E, Lok, S.-M. | Deposit date: | 2014-03-24 | Release date: | 2015-03-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins. Nat Commun, 6, 2015
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3J6U
| Cryo-EM structure of Dengue virus serotype 3 in complex with human antibody 5J7 Fab | Descriptor: | Fab 5J7 heavy chain, Fab 5J7 light chain, envelope protein, ... | Authors: | Fibriansah, G, Tan, J.L, Smith, S.A, de Alwis, R, Ng, T.-S, Kostyuchenko, V.A, Kukkaro, P, de Silva, A.M, Crowe Jr, J.E, Lok, S.-M. | Deposit date: | 2014-03-26 | Release date: | 2015-03-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins. Nat Commun, 6, 2015
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7WUV
| CryoEM structure of sNS1 hexamer | Descriptor: | Core protein | Authors: | Shu, B, Ooi, J.S.G, Lok, S.M. | Deposit date: | 2022-02-09 | Release date: | 2022-12-21 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever. Nat Commun, 13, 2022
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7WUS
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7WUR
| CryoEM structure of sNS1 complexed with Fab5E3 | Descriptor: | Core protein, Fab 5E3 Heavy Chain, Fab 5E3 Light Chain | Authors: | Shu, B, Lok, S.M. | Deposit date: | 2022-02-09 | Release date: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever. Nat Commun, 13, 2022
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7WUT
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7WUU
| CryoEM structure of loose sNS1 tetramer | Descriptor: | Core protein | Authors: | Shu, B, Lok, S.M. | Deposit date: | 2022-02-09 | Release date: | 2022-12-21 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (8.3 Å) | Cite: | CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever. Nat Commun, 13, 2022
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