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5UN7
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BU of 5un7 by Molmil
Structure of the human POT1-TPP1 telomeric complex
Descriptor: Adrenocortical dysplasia protein homolog, POTASSIUM ION, Protection of telomeres protein 1, ...
Authors:Rice, C, Doukov, T, Skordalakes, E.
Deposit date:2017-01-30
Release date:2017-04-12
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and functional analysis of the human POT1-TPP1 telomeric complex.
Nat Commun, 8, 2017
5W5O
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BU of 5w5o by Molmil
Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases.
Descriptor: 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine, Receptor-interacting serine/threonine-protein kinase 2
Authors:Kreusch, A, Spraggon, G.
Deposit date:2017-06-15
Release date:2017-10-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017
5W5J
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BU of 5w5j by Molmil
Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases
Descriptor: N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 2, SULFATE ION
Authors:Kreusch, A, Spraggon, G.
Deposit date:2017-06-15
Release date:2017-10-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017
6MEV
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BU of 6mev by Molmil
Structure of JMJD6 bound to Mono-Methyl Arginine.
Descriptor: (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, 2-OXOGLUTARIC ACID, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, ...
Authors:Lee, S, Zhang, G.
Deposit date:2018-09-07
Release date:2019-09-18
Last modified:2020-04-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes.
Elife, 9, 2020
6H8P
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BU of 6h8p by Molmil
JMJD2A/ KDM4A COMPLEXED WITH NI(II), NOG AND Histone H1.4(18-32)K26me3 peptide (15-mer)
Descriptor: CHLORIDE ION, GLYCEROL, Histone H1.4, ...
Authors:Chowdhury, R, Walport, L.J, Schofield, C.J.
Deposit date:2018-08-03
Release date:2018-08-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.983 Å)
Cite:Mechanistic and structural studies of KDM-catalysed demethylation of histone 1 isotype 4 at lysine 26.
FEBS Lett., 592, 2018
5FWE
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BU of 5fwe by Molmil
JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H4(1-15)R3me2s PEPTIDE
Descriptor: CHLORIDE ION, GLYCEROL, LYSINE-SPECIFIC DEMETHYLASE 4A, ...
Authors:Chowdhury, R, Walport, L.J, Schofield, C.J.
Deposit date:2016-02-15
Release date:2016-04-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Arginine Demethylation is Catalysed by a Subset of Jmjc Histone Lysine Demethylases.
Nat.Commun., 7, 2016
7LH6
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BU of 7lh6 by Molmil
The structure of Bacteroides plebeius L-galactose dehydrogenase
Descriptor: L-galactose dehydrogenase
Authors:Robb, C.S, Pluvinage, B, Vickers, C, Boraston, A.B.
Deposit date:2021-01-21
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022
7LHA
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BU of 7lha by Molmil
Structure of the Exo-L-galactose-6-sulfatase BuS1_11 from Bacteroides uniformis
Descriptor: CALCIUM ION, Exo-L-galactose-6-sulfatase, NICKEL (II) ION
Authors:Robb, C.S, Boraston, A.B.
Deposit date:2021-01-21
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022
7LK7
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BU of 7lk7 by Molmil
Structure of the Exo-alpha-L-galactosidase BpGH29 from Bacteroides plebeius in complex with L-galactose
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Exo-alpha-L-galactosidase, ...
Authors:Boraston, A.B, Robb, C.S.
Deposit date:2021-02-01
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022
7LJJ
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BU of 7ljj by Molmil
Structure of the Exo-alpha-L-galactosidase BpGH29 from Bacteroides plebeius
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Exo-alpha-L-galactosidase
Authors:Robb, C.S, Boraston, A.B.
Deposit date:2021-01-29
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022
7LNP
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BU of 7lnp by Molmil
Structure of the exo-alpha-L-galactosidase BpGH29 (D264N mutant) from Bacteroides plebeius in complex with paranitrophenyl-alpha-L-galactopyranoside
Descriptor: CALCIUM ION, CHLORIDE ION, Exo-alpha-L-galactosidase, ...
Authors:Boraston, A.B, Robb, C.S.
Deposit date:2021-02-08
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022
7LJ2
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BU of 7lj2 by Molmil
Structure of Exo-L-galactose-6-sulfatase BuS1_11 from Bacteroides uniformis in complex with neoporphyrabiose
Descriptor: 6-O-sulfo-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose, CALCIUM ION, Exo-L-galactose-6-sulfatase, ...
Authors:Robb, C.S, Boraston, A.B.
Deposit date:2021-01-28
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Nat.Chem.Biol., 18, 2022
1ROO
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BU of 1roo by Molmil
NMR SOLUTION STRUCTURE OF SHK TOXIN, NMR, 20 STRUCTURES
Descriptor: SHK TOXIN
Authors:Tudor, J.E, Pallaghy, P.K, Pennington, M.W, Norton, R.S.
Deposit date:1996-01-11
Release date:1997-01-27
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone.
Nat.Struct.Biol., 3, 1996
5T19
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BU of 5t19 by Molmil
Structure of PTP1B complexed with N-(3'-(1,1-dioxido-4-oxo-1,2,5-thiadiazolidin-2-yl)-4'-methyl-[1,1'-biphenyl]-4-yl)acetamide
Descriptor: 5-[4-methyl-4'-(methylamino)[1,1'-biphenyl]-3-yl]-1lambda~6~,2,5-thiadiazolidine-1,1,3-trione, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Laciak, A.R, Tanner, J.J.
Deposit date:2016-08-18
Release date:2017-04-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1001 Å)
Cite:Covalent Allosteric Inactivation of Protein Tyrosine Phosphatase 1B (PTP1B) by an Inhibitor-Electrophile Conjugate.
Biochemistry, 56, 2017
3US9
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BU of 3us9 by Molmil
Crystal Structure of the NCX1 Intracellular Tandem Calcium Binding Domains(CBD12)
Descriptor: CALCIUM ION, Sodium/calcium exchanger 1
Authors:Giladi, M, Sasson, Y, Hirsch, J.A, Khananshvili, D.
Deposit date:2011-11-23
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:A common Ca2+-driven interdomain module governs eukaryotic NCX regulation.
Plos One, 7, 2012
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數據於2024-07-03公開中

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