4LCB
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![BU of 4lcb by Molmil](/molmil-images/mine/4lcb) | Structure of Vps4 homolog from Acidianus hospitalis | Descriptor: | CHLORIDE ION, Cell division protein CdvC, Vps4 | Authors: | Han, H, Hill, C.P, Whitby, F.G, Monroe, N. | Deposit date: | 2013-06-21 | Release date: | 2013-11-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | The Oligomeric State of the Active Vps4 AAA ATPase. J.Mol.Biol., 426, 2014
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3GVW
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![BU of 3gvw by Molmil](/molmil-images/mine/3gvw) | Single-chain UROD F217Y (YF) mutation | Descriptor: | Uroporphyrinogen decarboxylase | Authors: | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | Deposit date: | 2009-03-31 | Release date: | 2009-12-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen. J.Mol.Biol., 389, 2009
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3GVR
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![BU of 3gvr by Molmil](/molmil-images/mine/3gvr) | |
6E93
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![BU of 6e93 by Molmil](/molmil-images/mine/6e93) | Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 in complex with methylated DNA | Descriptor: | DNA (5'-D(*GP*CP*AP*CP*TP*CP*AP*TP*(DCM)P*GP*GP*(DCM)P*GP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*(DCM)P*GP*CP*(DCM)P*GP*AP*TP*GP*AP*GP*TP*GP*C)-3'), ZINC ION, ... | Authors: | Hudson, N.O, Whitby, F.G, Buck-Koehntop, B.A. | Deposit date: | 2018-07-31 | Release date: | 2018-11-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.747 Å) | Cite: | Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38. J. Biol. Chem., 293, 2018
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6E94
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![BU of 6e94 by Molmil](/molmil-images/mine/6e94) | Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 K1055R in complex with methylated DNA | Descriptor: | DNA (5'-D(*GP*CP*AP*CP*TP*CP*AP*TP*(DCM)P*GP*GP*(DCM)P*GP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*(DCM)P*GP*CP*(DCM)P*GP*AP*TP*GP*AP*GP*TP*GP*C)-3'), ZINC ION, ... | Authors: | Hudson, N.O, Whitby, F.G, Buck-Koehntop, B.A. | Deposit date: | 2018-07-31 | Release date: | 2018-11-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.594 Å) | Cite: | Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38. J. Biol. Chem., 293, 2018
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1JPK
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![BU of 1jpk by Molmil](/molmil-images/mine/1jpk) | Gly156Asp mutant of Human UroD, human uroporphyrinogen III decarboxylase | Descriptor: | UROPORPHYRINOGEN DECARBOXYLASE | Authors: | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | Deposit date: | 2001-08-02 | Release date: | 2001-12-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
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1JPH
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![BU of 1jph by Molmil](/molmil-images/mine/1jph) | Ile260Thr mutant of Human UroD, human uroporphyrinogen III decarboxylase | Descriptor: | UROPORPHYRINOGEN DECARBOXYLASE | Authors: | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | Deposit date: | 2001-08-02 | Release date: | 2001-12-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
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1JPI
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![BU of 1jpi by Molmil](/molmil-images/mine/1jpi) | Phe232Leu mutant of human UROD, human uroporphyrinogen III decarboxylase | Descriptor: | UROPORPHYRINOGEN DECARBOXYLASE | Authors: | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | Deposit date: | 2001-08-02 | Release date: | 2001-12-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
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1QC7
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![BU of 1qc7 by Molmil](/molmil-images/mine/1qc7) | T. MARITIMA FLIG C-TERMINAL DOMAIN | Descriptor: | PROTEIN (FLIG) | Authors: | Lloyd, S.A, Whitby, F.G, Blair, D, Hill, C.P. | Deposit date: | 1999-05-18 | Release date: | 1999-08-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the C-terminal domain of FliG, a component of the rotor in the bacterial flagellar motor Nature, 400, 1999
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7TXE
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![BU of 7txe by Molmil](/molmil-images/mine/7txe) | Plasmodium falciparum Cyt c2 DSD | Descriptor: | Cytochrome c2, HEME C | Authors: | Hill, C.P, Wienkers, H.J, Whitby, F.G. | Deposit date: | 2022-02-08 | Release date: | 2023-05-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Direct tests of cytochrome c and c1 functions in the electron transport chain of malaria parasites Proc Natl Acad Sci U S A, 120, 2023
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7U2V
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2Q71
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![BU of 2q71 by Molmil](/molmil-images/mine/2q71) | Uroporphyrinogen Decarboxylase G168R single mutant enzyme in complex with coproporphyrinogen-III | Descriptor: | COPROPORPHYRINOGEN III, Uroporphyrinogen decarboxylase | Authors: | Phillips, J.D, Whitby, F.G, Stadtmueller, B.M, Edwards, C.Q, Hill, C.P, Kushner, J.P. | Deposit date: | 2007-06-05 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Two Novel Uropophyrinogen Decarboxylase (URO-D) Mutations Causing Hepatoerythropoietic Porphyria (HEP) Transl.Res., 149, 2007
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2Q6Z
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![BU of 2q6z by Molmil](/molmil-images/mine/2q6z) | Uroporphyrinogen Decarboxylase G168R single mutant apo-enzyme | Descriptor: | Uroporphyrinogen decarboxylase | Authors: | Phillips, J.D, Whitby, F.G, Stadtmueller, B.M, Edwards, C.Q, Hill, C.P, Kushner, J.P. | Deposit date: | 2007-06-05 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP). Transl.Res., 149, 2007
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3MGN
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![BU of 3mgn by Molmil](/molmil-images/mine/3mgn) | D-Peptide inhibitor PIE71 in complex with IQN17 | Descriptor: | D-PEPTIDE INHIBITOR PIE71, IQN17 | Authors: | Hill, C.P, Whitby, F.G, Kay, M, Francis, N. | Deposit date: | 2010-04-07 | Release date: | 2011-03-02 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance. J.Virol., 84, 2010
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3OYZ
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![BU of 3oyz by Molmil](/molmil-images/mine/3oyz) | Haloferax volcanii Malate Synthase Pyruvate/Acetyl-CoA Ternary Complex | Descriptor: | ACETYL COENZYME *A, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Howard, B.R, Bracken, C, Neighbor, A, Thomas, G, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | Deposit date: | 2010-09-24 | Release date: | 2011-06-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G. Bmc Struct.Biol., 11, 2011
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3OYX
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![BU of 3oyx by Molmil](/molmil-images/mine/3oyx) | Haloferax volcanii Malate Synthase Magnesium/Glyoxylate Complex | Descriptor: | CHLORIDE ION, GLYOXYLIC ACID, MAGNESIUM ION, ... | Authors: | Howard, B.R, Bracken, C, Neighbor, A, Thomas, G, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | Deposit date: | 2010-09-24 | Release date: | 2011-06-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G. Bmc Struct.Biol., 11, 2011
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3PUG
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![BU of 3pug by Molmil](/molmil-images/mine/3pug) | Haloferax volcanii Malate Synthase Native at 3mM Glyoxylate | Descriptor: | CHLORIDE ION, GLYOXYLIC ACID, MAGNESIUM ION, ... | Authors: | Howard, B.R, Bracken, C.D, Neighbor, A.M, Thomas, G.C, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | Deposit date: | 2010-12-04 | Release date: | 2011-06-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G. Bmc Struct.Biol., 11, 2011
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3RBQ
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![BU of 3rbq by Molmil](/molmil-images/mine/3rbq) | Co-crystal structure of human UNC119 (retina gene 4) and an N-terminal Transducin-alpha mimicking peptide | Descriptor: | Guanine nucleotide-binding protein G(t) subunit alpha-1, Protein unc-119 homolog A | Authors: | Constantine, R, Whitby, F.G, Hill, C.P, Baehr, W. | Deposit date: | 2011-03-29 | Release date: | 2011-06-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | UNC119 is required for G protein trafficking in sensory neurons. Nat.Neurosci., 14, 2011
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5KKE
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![BU of 5kke by Molmil](/molmil-images/mine/5kke) | |
5KLU
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![BU of 5klu by Molmil](/molmil-images/mine/5klu) | |
4WLR
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![BU of 4wlr by Molmil](/molmil-images/mine/4wlr) | Crystal Structure of mUCH37-hRPN13 CTD-hUb complex | Descriptor: | Polyubiquitin-B, Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | Authors: | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | Deposit date: | 2014-10-07 | Release date: | 2015-03-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
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4WLP
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![BU of 4wlp by Molmil](/molmil-images/mine/4wlp) | Crystal structure of UCH37-NFRKB Inhibited Deubiquitylating Complex | Descriptor: | Nuclear factor related to kappa-B-binding protein, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | Authors: | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | Deposit date: | 2014-10-07 | Release date: | 2015-03-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
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4WNN
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![BU of 4wnn by Molmil](/molmil-images/mine/4wnn) | SPT16-H2A-H2B FACT HISTONE Complex | Descriptor: | Histone H2A.1, Histone H2B.1, PHOSPHATE ION, ... | Authors: | Kemble, D.J, Hill, C.P, Whitby, F.G, Formosa, T, McCullough, L.L. | Deposit date: | 2014-10-13 | Release date: | 2015-10-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs. Mol.Cell, 60, 2015
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4WLQ
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![BU of 4wlq by Molmil](/molmil-images/mine/4wlq) | Crystal structure of mUCH37-hRPN13 CTD complex | Descriptor: | Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | Authors: | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | Deposit date: | 2014-10-07 | Release date: | 2015-03-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
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3B99
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![BU of 3b99 by Molmil](/molmil-images/mine/3b99) | Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1) in complex with substrate analog U51605 | Descriptor: | (5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-oct-1-en-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}hept-5-enoic acid, PROTOPORPHYRIN IX CONTAINING FE, Prostaglandin I2 synthase | Authors: | Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. | Deposit date: | 2007-11-03 | Release date: | 2007-11-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change J.Biol.Chem., 283, 2008
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