Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4MB1
DownloadVisualize
BU of 4mb1 by Molmil
The Structure of MalL mutant enzyme G202P from Bacillus subtilus
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Oligo-1,6-glucosidase 1
Authors:Hobbs, J.K, Jiao, W, Easter, A.D, Parker, E.J, Schipper, L.A, Arcus, V.L.
Deposit date:2013-08-19
Release date:2013-09-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates.
Acs Chem.Biol., 8, 2013
4M8B
DownloadVisualize
BU of 4m8b by Molmil
Fungal Protein
Descriptor: 1,2-ETHANEDIOL, Chain A of dsDNA containing the cis-regulatory element, Chain B of dsDNA containing the cis-regulatory element, ...
Authors:Rosenberg, O.S, Lohse, M.L, Stroud, R.M, Johnson, A.D.
Deposit date:2013-08-13
Release date:2014-06-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MAZ
DownloadVisualize
BU of 4maz by Molmil
The Structure of MalL mutant enzyme V200S from Bacillus subtilus
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ...
Authors:Hobbs, J.K, Jiao, W, Easter, A.D, Parker, E.J, Schipper, L.A, Arcus, V.L.
Deposit date:2013-08-18
Release date:2013-09-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates.
Acs Chem.Biol., 8, 2013
4MIM
DownloadVisualize
BU of 4mim by Molmil
Structure of the carboxyl transferase domain from Rhizobium etli pyruvate carboxylase with 3-bromopyruvate
Descriptor: Bromopyruvate, CHLORIDE ION, GLYCEROL, ...
Authors:Lietzan, A.D, St.Maurice, M.
Deposit date:2013-09-01
Release date:2014-08-13
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs.
Biochem.Biophys.Res.Commun., 441, 2013
4MKJ
DownloadVisualize
BU of 4mkj by Molmil
Crystal structure of L-methionine gamma-lyase from Citrobacter freundii modified by allicine
Descriptor: Methionine gamma-lyase, PENTAETHYLENE GLYCOL, SODIUM ION, ...
Authors:Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Zakomirdina, L.N, Demidkina, T.V.
Deposit date:2013-09-05
Release date:2014-11-12
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Alliin is a suicide substrate of Citrobacter freundii methionine gamma-lyase: structural bases of inactivation of the enzyme.
Acta Crystallogr.,Sect.D, 70, 2014
4MLF
DownloadVisualize
BU of 4mlf by Molmil
Crystal structure for the complex of thrombin mutant D102N and hirudin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Hirudin variant-1, ...
Authors:Vogt, A.D, Pozzi, N, Chen, Z, Di Cera, E.
Deposit date:2013-09-06
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Essential role of conformational selection in ligand binding.
Biophys.Chem., 186C, 2014
3GAM
DownloadVisualize
BU of 3gam by Molmil
Synthesis of Casimiroin and Optimization of Its Quinone Reductase 2 and Aromatase Inhibitory activity
Descriptor: 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ...
Authors:Sturdy, M, Pegan, S.D, Maiti, A, Marler, L, Mesecar, A.D, Pezzuto, J.M, Cushman, M.
Deposit date:2009-02-17
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities.
J.Med.Chem., 52, 2009
4MML
DownloadVisualize
BU of 4mml by Molmil
D40A Hfq from Pseudomonas aeruginosa
Descriptor: MAGNESIUM ION, Protein hfq, SULFATE ION, ...
Authors:Murina, V.N, Filimonov, V.V, Melnik, B.S, Uhlein, M, Mueller, U, Weiss, M, Nikulin, A.D.
Deposit date:2013-09-09
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Effect of conserved intersubunit amino Acid substitutions on hfq protein structure and stability.
Biochemistry Mosc., 79, 2014
4M5X
DownloadVisualize
BU of 4m5x by Molmil
Crystal structure of the USP7/HAUSP catalytic domain
Descriptor: BROMIDE ION, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Mesecar, A.D, Molland, K.L, Zhou, Q.
Deposit date:2013-08-08
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:A 2.2 angstrom resolution structure of the USP7 catalytic domain in a new space group elaborates upon structural rearrangements resulting from ubiquitin binding.
Acta Crystallogr F Struct Biol Commun, 70, 2014
4MDS
DownloadVisualize
BU of 4mds by Molmil
Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: identification of ML300 and non-covalent nanomolar inhibitors with an induced-fit binding
Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, N-[4-(acetylamino)phenyl]-2-(1H-benzotriazol-1-yl)-N-[(1R)-2-[(2-methylbutan-2-yl)amino]-1-(1-methyl-1H-pyrrol-2-yl)-2-oxoethyl]acetamide
Authors:Mesecar, A.D, Grum-Tokars, V.
Deposit date:2013-08-23
Release date:2013-10-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.598 Å)
Cite:Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding.
Bioorg.Med.Chem.Lett., 23, 2013
4IRA
DownloadVisualize
BU of 4ira by Molmil
CobR in complex with FAD
Descriptor: 4-hydroxyphenylacetate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Lawrence, A.D, Scott, A.F, Warren, M.J, Pickersgill, R.W.
Deposit date:2013-01-14
Release date:2014-01-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Biophysical characterisation and structure-function analysis of Brucella melitensis CobR: Protein-flavin interactions determine function and stability
To be Published
4MKK
DownloadVisualize
BU of 4mkk by Molmil
Crystal structure of C115A mutant L-methionine gamma-lyase from Citrobacter freundii modified by allicine
Descriptor: CHLORIDE ION, Methionine gamma-lyase, POTASSIUM ION, ...
Authors:Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Zakomirdina, L.N, Demidkina, T.V.
Deposit date:2013-09-05
Release date:2014-11-12
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Alliin is a suicide substrate of Citrobacter freundii methionine gamma-lyase: structural bases of inactivation of the enzyme.
Acta Crystallogr.,Sect.D, 70, 2014
4MMK
DownloadVisualize
BU of 4mmk by Molmil
Q8A Hfq from Pseudomonas aeruginosa
Descriptor: POTASSIUM ION, Protein hfq, SODIUM ION, ...
Authors:Murina, V.N, Filimonov, V.V, Melnik, B.S, Uhlein, M, Mueller, U, Weiss, M, Nikulin, A.D.
Deposit date:2013-09-09
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.156 Å)
Cite:Effect of conserved intersubunit amino Acid substitutions on hfq protein structure and stability.
Biochemistry Mosc., 79, 2014
2J4I
DownloadVisualize
BU of 2j4i by Molmil
CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX
Descriptor: 1-PYRROLIDINEACETAMIDE, 3-[[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]AMINO]-ALPHA-METHYL-N-(1-METHYLETHYL)-N-[2-[(METHYLSULFONYL)AMINO]ETHYL]-2-OXO-, (ALPHAS,3S)-, ...
Authors:Young, R.J, Campbell, M, Borthwick, A.D, Brown, D, Chan, C, Convery, M.A, Crowe, M.C, Dayal, S, Diallo, H, Kelly, H.A, Paul King, N, Kleanthous, S, Kurtis, C.L, Mason, A.M, Mordaunt, J.E, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Smith, P.W, Watson, N.S, Weston, H.E, Zhou, P.
Deposit date:2006-08-31
Release date:2006-09-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure- and Property-Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Acyclic Alanyl Amides as P4 Motifs.
Bioorg.Med.Chem.Lett., 16, 2006
2J95
DownloadVisualize
BU of 2j95 by Molmil
CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX
Descriptor: 5'-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-2,2'-BITHIOPHENE-5-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, ACTIVATED FACTOR XA LIGHT CHAIN, ...
Authors:Chan, C, Borthwick, A.D, Brown, D, Campbell, M, Chaudry, L, Chung, C.W, Convery, M.A, Hamblin, J.N, Johnstone, L, Kelly, H.A, Kleanthous, S, Burns-Kurtis, C.L, Patikis, A, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Toomey, J.R, Watson, N.S, Weston, H.E, Whitworth, C, Young, R.J, Zhou, P.
Deposit date:2006-11-02
Release date:2007-03-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Factor Xa Inhibitors: S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-Morpholin-4-Yl-2-Oxoethyl]-2-Oxopyrrolidin-3-Yl}Sulfonamides.
J.Med.Chem., 50, 2007
2J94
DownloadVisualize
BU of 2j94 by Molmil
CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX
Descriptor: 5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE, CALCIUM ION, COAGULATION FACTOR X
Authors:Chan, C, Borthwick, A.D, Brown, D, Campbell, M, Chaudry, L, Chung, C.W, Convery, M.A, Hamblin, J.N, Johnstone, L, Kelly, H.A, Kleanthous, S, Burns-Kurtis, C.L, Patikis, A, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Toomey, J.R, Watson, N.S, Weston, H.E, Whitworth, C, Young, R.J, Zhou, P.
Deposit date:2006-11-02
Release date:2007-03-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Factor Xa Inhibitors: S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-Morpholin-4-Yl-2-Oxoethyl]-2-Oxopyrrolidin-3-Yl}Sulfonamides.
J.Med.Chem., 50, 2007
3M20
DownloadVisualize
BU of 3m20 by Molmil
Crystal structure of DmpI from Archaeoglobus fulgidus determined to 2.37 Angstroms resolution
Descriptor: 4-oxalocrotonate tautomerase, putative
Authors:Hackert, M.L, Whitman, C.P, Almrud, J.J, Dasgupta, R, Kern, A.D.
Deposit date:2010-03-06
Release date:2010-09-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Kinetic and structural characterization of DmpI from Helicobacter pylori and Archaeoglobus fulgidus, two 4-oxalocrotonate tautomerase family members.
Bioorg.Chem., 38, 2010
3M21
DownloadVisualize
BU of 3m21 by Molmil
Crystal structure of DmpI from Helicobacter pylori Determined to 1.9 Angstroms resolution
Descriptor: Probable tautomerase HP_0924
Authors:Hackert, M.L, Whitman, C.P, Almrud, J.J, Dasgupta, R, Kern, A.D, Czerwinski, R.M.
Deposit date:2010-03-06
Release date:2010-09-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Kinetic and structural characterization of DmpI from Helicobacter pylori and Archaeoglobus fulgidus, two 4-oxalocrotonate tautomerase family members.
Bioorg.Chem., 38, 2010
2JLN
DownloadVisualize
BU of 2jln by Molmil
Structure of Mhp1, a nucleobase-cation-symport-1 family transporter
Descriptor: MERCURY (II) ION, MHP1, SODIUM ION
Authors:Weyand, S, Shimamura, T, Yajima, S, Suzuki, S, Mirza, O, Krusong, K, Carpenter, E.P, Rutherford, N.G, Hadden, J.M, O'Reilly, J, Ma, P, Saidijam, M, Patching, S.G, Hope, R.J, Norbertczak, H.T, Roach, P.C.J, Iwata, S, Henderson, P.J.F, Cameron, A.D.
Deposit date:2008-09-11
Release date:2008-10-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter.
Science, 322, 2008
2JSB
DownloadVisualize
BU of 2jsb by Molmil
Solution structure of arenicin-1
Descriptor: Arenicin-1
Authors:Jakovkin, I.B, Hecht, O, Gelhaus, C, Krasnosdembskaya, A.D, Fedders, H, Leippe, M, Groetzinger, J.
Deposit date:2007-07-02
Release date:2008-02-05
Last modified:2020-02-19
Method:SOLUTION NMR
Cite:Structure and mode of action of the antimicrobial peptide arenicin
Biochem.J., 410, 2008
2IQ7
DownloadVisualize
BU of 2iq7 by Molmil
Crystal structure of the polygalacturonase from Colletotrichum lupini and its implications for the interaction with polygalacturonase-inhibiting proteins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Bonivento, D, Federici, L, Matteo, A.D.
Deposit date:2006-10-13
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal structure of the endopolygalacturonase from the phytopathogenic fungus Colletotrichum lupini and its interaction with polygalacturonase-inhibiting proteins
Proteins, 70, 2008
2J50
DownloadVisualize
BU of 2j50 by Molmil
Structure of Aurora-2 in complex with PHA-739358
Descriptor: N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE, SERINE/THREONINE-PROTEIN KINASE 6, SULFATE ION
Authors:Cameron, A.D, Izzo, G, Storici, P, Rusconi, L, Fancelli, D, Varasi, M, Berta, D, Bindi, S, Forte, B, Severino, D, Tonani, R, Vianello, P.
Deposit date:2006-09-08
Release date:2006-11-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile.
J.Med.Chem., 49, 2006
3MJ5
DownloadVisualize
BU of 3mj5 by Molmil
Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Protease Inhibitors: Design, Synthesis, Protein-Ligand X-ray Structure and Biological Evaluation
Descriptor: N-(1,3-benzodioxol-5-ylmethyl)-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Replicase polyprotein 1a, ZINC ION
Authors:Mesecar, A.D, Ratia, K.M, Pegan, S.D.
Deposit date:2010-04-12
Release date:2010-06-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein-ligand X-ray structure and biological evaluation
J.Med.Chem., 53, 2010
2JGC
DownloadVisualize
BU of 2jgc by Molmil
Structure of the human eIF4E homologous protein, 4EHP without ligand bound
Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1
Authors:Cameron, A.D, Rosettani, P, Knapp, S, Vismara, M.G, Rusconi, L.
Deposit date:2007-02-12
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
J. Mol. Biol., 368, 2007
2JGB
DownloadVisualize
BU of 2jgb by Molmil
Structure of human eIF4E homologous protein 4EHP with m7GTP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1
Authors:Cameron, A.D, Rosettani, P, Knapp, S, Vismara, M.G, Rusconi, L.
Deposit date:2007-02-12
Release date:2007-02-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
J. Mol. Biol., 368, 2007

221051

數據於2024-06-12公開中

PDB statisticsPDBj update infoContact PDBjnumon