1FRO

HUMAN GLYOXALASE I WITH BENZYL-GLUTATHIONE INHIBITOR

Summary for 1FRO

DescriptorLACTOYLGLUTATHIONE LYASE, ZINC ION, S-BENZYL-GLUTATHIONE, ... (4 entities in total)
Functional Keywordslactoylglutathione lyase, glyoxalase i
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total molecular weight84541.5
Authors
Cameron, A.D.,Jones, T.A. (deposition date: 1997-02-25, release date: 1997-06-16, Last modification date: 2011-07-13)
Primary citation
Cameron, A.D.,Olin, B.,Ridderstrom, M.,Mannervik, B.,Jones, T.A.
Crystal structure of human glyoxalase I--evidence for gene duplication and 3D domain swapping.
EMBO J., 16:3386-3395, 1997
PubMed: 9218781 (PDB entries with the same primary citation)
DOI: 10.1093/emboj/16.12.3386
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers502.0%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1fro
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Molmil generated image of 1fro
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Molmil generated image of 1fro
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 1fro
no rotation
Molmil generated image of 1fro
rotated about x axis by 90°
Molmil generated image of 1fro
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1fro.pdb1.gz [64.01 KB])
Coordinate files for Biological unit (1fro.pdb2.gz [63.74 KB])