1CX5
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![BU of 1cx5 by Molmil](/molmil-images/mine/1cx5) | ANTISENSE DNA/RNA HYBRID CONTAINING MODIFIED BACKBONE | Descriptor: | 5'-D(*CP*GP*CP*GP*TP*T*(MMT)P*TP*GP*CP*GP*C), 5'-R(*GP*CP*GP*CP*AP*AP*AP*AP*CP*GP*CP*G) | Authors: | Yang, X, Han, X, Cross, C, Sanghvi, Y, Gao, X. | Deposit date: | 1999-08-28 | Release date: | 1999-09-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of an antisense DNA.RNA hybrid duplex containing a 3'-CH(2)N(CH(3))-O-5' or an MMI backbone linker. Biochemistry, 38, 1999
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6NT5
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![BU of 6nt5 by Molmil](/molmil-images/mine/6nt5) | Cryo-EM structure of full-length human STING in the apo state | Descriptor: | Stimulator of interferon protein | Authors: | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | Deposit date: | 2019-01-28 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP. Nature, 567, 2019
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6NT6
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![BU of 6nt6 by Molmil](/molmil-images/mine/6nt6) | Cryo-EM structure of full-length chicken STING in the apo state | Descriptor: | Stimulator of interferon genes protein | Authors: | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | Deposit date: | 2019-01-28 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP. Nature, 567, 2019
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6NT7
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![BU of 6nt7 by Molmil](/molmil-images/mine/6nt7) | Cryo-EM structure of full-length chicken STING in the cGAMP-bound dimeric state | Descriptor: | Stimulator of interferon genes protein, cGAMP | Authors: | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | Deposit date: | 2019-01-28 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP. Nature, 567, 2019
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7CUV
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![BU of 7cuv by Molmil](/molmil-images/mine/7cuv) | |
6NT8
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![BU of 6nt8 by Molmil](/molmil-images/mine/6nt8) | Cryo-EM structure of full-length chicken STING in the cGAMP-bound tetrameric state | Descriptor: | Stimulator of interferon genes protein, cGAMP | Authors: | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | Deposit date: | 2019-01-28 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP. Nature, 567, 2019
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7E30
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![BU of 7e30 by Molmil](/molmil-images/mine/7e30) | Crystal structure of a novel alpha/beta hydrolase in apo form in complex with citrate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CITRIC ACID, SULFATE ION, ... | Authors: | Gao, J, Han, X, Zheng, Y.Y, Liu, W.D. | Deposit date: | 2021-02-07 | Release date: | 2022-02-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase. Acs Catalysis, 12, 2022
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7E31
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![BU of 7e31 by Molmil](/molmil-images/mine/7e31) | Crystal structure of a novel alpha/beta hydrolase mutant in apo form | Descriptor: | TRIETHYLENE GLYCOL, alpha/beta hydrolase | Authors: | Gao, J, Han, X, Zheng, Y.Y, Liu, W.D. | Deposit date: | 2021-02-07 | Release date: | 2022-02-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase. Acs Catalysis, 12, 2022
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7E9C
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![BU of 7e9c by Molmil](/molmil-images/mine/7e9c) | Cryo-EM structure of the 1:1 Orc1 BAH domain in complex with nucleosome | Descriptor: | DNA (147-mer), Histone H2A.2, Histone H2B.2, ... | Authors: | Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M. | Deposit date: | 2021-03-04 | Release date: | 2022-09-07 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1 To Be Published
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7E9F
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![BU of 7e9f by Molmil](/molmil-images/mine/7e9f) | Cryo-EM structure of the 2:1 Orc1 BAH domain in complex with nucleosome | Descriptor: | DNA (147-mer), Histone H2A.2, Histone H2B.2, ... | Authors: | Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M. | Deposit date: | 2021-03-04 | Release date: | 2022-09-07 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1 To Be Published
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6VXK
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![BU of 6vxk by Molmil](/molmil-images/mine/6vxk) | Cryo-EM Structure of the full-length A39R/PlexinC1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-C1, Semaphorin-like protein 139 | Authors: | Kuo, Y.-C, Chen, H, Shang, G, Uchikawa, E, Tian, H, Bai, X, Zhang, X. | Deposit date: | 2020-02-22 | Release date: | 2020-04-29 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structure of the PlexinC1/A39R complex reveals inter-domain interactions critical for ligand-induced activation. Nat Commun, 11, 2020
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1XOO
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![BU of 1xoo by Molmil](/molmil-images/mine/1xoo) | NMR structure of G1S mutant of influenza hemagglutinin fusion peptide in DPC micelles at pH 5 | Descriptor: | Hemagglutinin | Authors: | Li, Y, Han, X, Lai, A.L, Bushweller, J.H, Cafiso, D.S, Tamm, L.K. | Deposit date: | 2004-10-06 | Release date: | 2005-09-27 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Membrane structures of the hemifusion-inducing fusion peptide mutant G1S and the fusion-blocking mutant G1V of influenza virus hemagglutinin suggest a mechanism for pore opening in membrane fusion. J.Virol., 79, 2005
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1XOP
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![BU of 1xop by Molmil](/molmil-images/mine/1xop) | NMR structure of G1V mutant of influenza hemagglutinin fusion peptide in DPC micelles at pH 5 | Descriptor: | Hemagglutinin | Authors: | Li, Y, Han, X, Lai, A.L, Bushweller, J.H, Cafiso, D.S, Tamm, L.K. | Deposit date: | 2004-10-06 | Release date: | 2005-09-27 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Membrane structures of the hemifusion-inducing fusion peptide mutant G1S and the fusion-blocking mutant G1V of influenza virus hemagglutinin suggest a mechanism for pore opening in membrane fusion. J.Virol., 79, 2005
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6KY5
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![BU of 6ky5 by Molmil](/molmil-images/mine/6ky5) | Crystal structure of a hydrolase mutant | Descriptor: | PET hydrolase, SULFATE ION | Authors: | Cui, Y.L, Chen, Y.C, Liu, X.Y, Dong, S.J, Han, J, Xiang, H, Chen, Q, Liu, H.Y, Han, X, Liu, W.D, Tang, S.Y, Wu, B. | Deposit date: | 2019-09-16 | Release date: | 2020-09-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.631 Å) | Cite: | Computational redesign of PETase for plasticbiodegradation by GRAPE strategy. Biorxiv, 2020
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1AWP
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![BU of 1awp by Molmil](/molmil-images/mine/1awp) | RAT OUTER MITOCHONDRIAL MEMBRANE CYTOCHROME B5 | Descriptor: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Wang, X, Zhang, X. | Deposit date: | 1997-10-03 | Release date: | 1998-10-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The reduction potential of cytochrome b5 is modulated by its exposed heme edge. Biochemistry, 37, 1998
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7SII
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![BU of 7sii by Molmil](/molmil-images/mine/7sii) | Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53) | Descriptor: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, Stimulator of interferon genes protein, cGAMP | Authors: | Lu, D, Shang, G, Jie, L, Lu, Y, Bai, X.C, Zhang, X. | Deposit date: | 2021-10-14 | Release date: | 2022-02-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Activation of STING by targeting a pocket in the transmembrane domain. Nature, 604, 2022
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5YWW
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![BU of 5yww by Molmil](/molmil-images/mine/5yww) | Archael RuvB-like Holiday junction helicase | Descriptor: | GLYCEROL, Nucleotide binding protein PINc | Authors: | Zhai, B, Yuan, Z, Han, X, DuPrez, K, Shen, Y, Fan, L. | Deposit date: | 2017-11-30 | Release date: | 2018-06-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | The archaeal ATPase PINA interacts with the helicase Hjm via its carboxyl terminal KH domain remodeling and processing replication fork and Holliday junction. Nucleic Acids Res., 46, 2018
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4TOR
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![BU of 4tor by Molmil](/molmil-images/mine/4tor) | Crystal structure of Tankyrase 1 with IWR-8 | Descriptor: | 1-[(1-acetyl-5-bromo-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(3-methylphenyl)piperidine-4-carboxamide, CHLORIDE ION, Tankyrase-1, ... | Authors: | Chen, H, Zhang, X, Lum, L, Chen, C. | Deposit date: | 2014-06-06 | Release date: | 2015-05-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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4TOS
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![BU of 4tos by Molmil](/molmil-images/mine/4tos) | Crystal structure of Tankyrase 1 with 355 | Descriptor: | Tankyrase-1, ZINC ION, trans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamide | Authors: | Chen, H, Zhang, X, Lum, l, Chen, C. | Deposit date: | 2014-06-06 | Release date: | 2015-05-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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190D
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![BU of 190d by Molmil](/molmil-images/mine/190d) | |
1B5M
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![BU of 1b5m by Molmil](/molmil-images/mine/1b5m) | RAT OUTER MITOCHONDRIAL MEMBRANE CYTOCHROME B5 | Descriptor: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Rivera, M, White, S.P, Zhang, X. | Deposit date: | 1996-11-07 | Release date: | 1997-03-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | 13C NMR spectroscopic and X-ray crystallographic study of the role played by mitochondrial cytochrome b5 heme propionates in the electrostatic binding to cytochrome c. Biochemistry, 35, 1996
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2M9M
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![BU of 2m9m by Molmil](/molmil-images/mine/2m9m) | Solution Structure of ERCC4 domain of human FAAP24 | Descriptor: | Fanconi anemia-associated protein of 24 kDa | Authors: | Wu, F, Han, X, Shi, C, Gong, W, Tian, C. | Deposit date: | 2013-06-18 | Release date: | 2013-09-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response. Cell Res., 23, 2013
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2M9N
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![BU of 2m9n by Molmil](/molmil-images/mine/2m9n) | Solution Structure of (HhH)2 domain of human FAAP24 | Descriptor: | Fanconi anemia-associated protein of 24 kDa | Authors: | Wu, F, Han, X, Shi, C, Gong, W, Tian, C. | Deposit date: | 2013-06-18 | Release date: | 2013-09-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response. Cell Res., 23, 2013
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6IRG
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![BU of 6irg by Molmil](/molmil-images/mine/6irg) | Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class II | Descriptor: | Glutamate receptor ionotropic, NMDA 1, NMDA 2A | Authors: | Zhang, J, Chang, S, Zhang, X, Zhu, S. | Deposit date: | 2018-11-12 | Release date: | 2019-01-16 | Last modified: | 2019-06-05 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors Cell Rep, 25, 2018
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6IJJ
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![BU of 6ijj by Molmil](/molmil-images/mine/6ijj) | Photosystem I of Chlamydomonas reinhardtii | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Pan, X, Ma, J, Su, X, Liu, Z, Zhang, X, Li, M. | Deposit date: | 2018-10-10 | Release date: | 2019-03-20 | Last modified: | 2019-05-01 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Antenna arrangement and energy transfer pathways of a green algal photosystem-I-LHCI supercomplex. Nat Plants, 5, 2019
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