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4IFC
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BU of 4ifc by Molmil
Crystal Structure of ADP-bound Human PRPF4B kinase domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, Serine/threonine-protein kinase PRP4 homolog
Authors:Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L.
Deposit date:2012-12-14
Release date:2013-08-28
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
4IJP
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BU of 4ijp by Molmil
Crystal Structure of Human PRPF4B kinase domain in complex with 4-{5-[(2-Chloro-pyridin-4-ylmethyl)-carbamoyl]-thiophen-2-yl}-benzo[b]thiophene-2-carboxylic acid amine
Descriptor: 4-(5-{[(2-chloropyridin-4-yl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, SULFATE ION, Serine/threonine-protein kinase PRP4 homolog
Authors:Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L.
Deposit date:2012-12-22
Release date:2013-08-28
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
4IIR
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BU of 4iir by Molmil
Crystal Structure of AMPPNP-bound Human PRPF4B kinase domain
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ...
Authors:Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L.
Deposit date:2012-12-20
Release date:2013-08-28
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches.
J.Biol.Chem., 288, 2013
3T5S
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BU of 3t5s by Molmil
Structure of macrophage migration inhibitory factor from Giardia lamblia
Descriptor: CHLORIDE ION, Macrophage migration inhibitory factor, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-07-28
Release date:2011-08-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia.
J.Struct.Funct.Genom., 14, 2013
3TFN
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BU of 3tfn by Molmil
Crystal structure of dehydrosqualene synthase (crtm) from s. aureus complexed with bph-1183
Descriptor: (1-{2-[4-(diphenylmethyl)piperazin-1-yl]-2-oxoethyl}cyclopentyl)acetic acid, Dehydrosqualene synthase, MAGNESIUM ION
Authors:Lin, F.-Y, Liu, Y.-L, Oldfield, E.
Deposit date:2011-08-16
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics.
Chemmedchem, 7, 2012
4FVP
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BU of 4fvp by Molmil
Crystal structure of the Jak2 pseudokinase domain (apo form)
Descriptor: GLYCEROL, Tyrosine-protein kinase JAK2
Authors:Bandaranayake, R.M, Hubbard, S.R.
Deposit date:2012-06-29
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F.
Nat.Struct.Mol.Biol., 19, 2012
7EEB
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BU of 7eeb by Molmil
Structure of the CatSpermasome
Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wu, J.P, Ke, M.
Deposit date:2021-03-18
Release date:2021-07-28
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of a mammalian sperm cation channel complex.
Nature, 595, 2021
3VPI
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BU of 3vpi by Molmil
Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa
Descriptor: FORMIC ACID, type VI secretion exported 1
Authors:Ding, J, Wang, W, Wang, D.C.
Deposit date:2012-03-04
Release date:2012-06-27
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural insights into the Pseudomonas aeruginosa type VI virulence effector Tse1 bacteriolysis and self-protection mechanisms
J.Biol.Chem., 287, 2012
3V3L
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BU of 3v3l by Molmil
Crystal structure of human RNF146 WWE domain in complex with iso-ADPRibose
Descriptor: 2'-O-(5-O-phosphono-alpha-D-ribofuranosyl)adenosine 5'-(dihydrogen phosphate), E3 ubiquitin-protein ligase RNF146
Authors:Wang, Z, Cheng, Z, Xu, W.
Deposit date:2011-12-13
Release date:2012-02-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination.
Genes Dev., 26, 2012
7DD1
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BU of 7dd1 by Molmil
Crystal structure of SRPK1 in complex with a peptide inhibitor
Descriptor: ARG-GLU-ARG-ALA-ARG-THR-ARG, SRSF protein kinase 1,SRSF protein kinase 1
Authors:Li, Q.Y, Yung, K.W.Y, Ngo, J.C.K.
Deposit date:2020-10-27
Release date:2021-04-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Protein-Protein Interaction Inhibitor of SRPKs Alters the Splicing Isoforms of VEGF and Inhibits Angiogenesis.
Iscience, 24, 2021
3VPJ
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BU of 3vpj by Molmil
crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa in complex with immune protein Tsi1
Descriptor: Tse1-specific immunity protein, type VI secretion exported 1
Authors:Ding, J, Wang, W, Wang, D.C.
Deposit date:2012-03-04
Release date:2012-06-27
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the Pseudomonas aeruginosa type VI virulence effector Tse1 bacteriolysis and self-protection mechanisms
J.Biol.Chem., 287, 2012
4HE0
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BU of 4he0 by Molmil
Crystal structure of human muscle fructose-1,6-bisphosphatase
Descriptor: CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, MAGNESIUM ION, ...
Authors:Shi, R, Zhu, D.W, Lin, S.X.
Deposit date:2012-10-03
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
3UAF
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BU of 3uaf by Molmil
Crystal Structure of a TTR-52 mutant of C. elegans
Descriptor: TTR-52
Authors:Kang, Y.Y, Zhao, D.F, Liang, H.H, Liu, B, Liu, Q.W, Wang, X.C, Liu, Y.F.
Deposit date:2011-10-21
Release date:2012-10-24
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural study of TTR-52 reveals the mechanism by which a bridging molecule mediates apoptotic cell engulfment
Genes Dev., 26, 2012
5ET5
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BU of 5et5 by Molmil
Human muscle fructose-1,6-bisphosphatase in active R-state
Descriptor: Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2015-11-17
Release date:2016-04-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure.
Acta Crystallogr D Struct Biol, 72, 2016
5ET8
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BU of 5et8 by Molmil
Human muscle fructose-1,6-bisphosphatase in active R-state in complex with fructose-6-phosphate
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2015-11-17
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:T-to-R switch of muscle FBPase involves extreme changes of secondary and quaternary structure
To Be Published
5ET6
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BU of 5et6 by Molmil
Human muscle fructose-1,6-bisphosphatase in inactive T-state in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2015-11-17
Release date:2016-04-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.845 Å)
Cite:T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure.
Acta Crystallogr D Struct Biol, 72, 2016
5ET7
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BU of 5et7 by Molmil
Human muscle fructose-1,6-bisphosphatase in inactive T-state
Descriptor: Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2015-11-17
Release date:2016-04-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.989 Å)
Cite:T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure.
Acta Crystallogr D Struct Biol, 72, 2016
3W8I
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BU of 3w8i by Molmil
Crystal structure of CCM3 in complex with the C-terminal regulatory domain of MST4
Descriptor: Programmed cell death protein 10, Serine/threonine-protein kinase MST4
Authors:Xu, X, Wang, D.C, Ding, J.
Deposit date:2013-03-13
Release date:2013-07-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
Structure, 21, 2013
4HE2
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BU of 4he2 by Molmil
Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, ...
Authors:Shi, R, Zhu, D.W, Lin, S.X.
Deposit date:2012-10-03
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
4HE1
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BU of 4he1 by Molmil
Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with fructose-6-phosphate and phosphate
Descriptor: 6-O-phosphono-beta-D-fructofuranose, CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, ...
Authors:Shi, R, Zhu, D.W, Lin, S.X.
Deposit date:2012-10-03
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
7F26
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BU of 7f26 by Molmil
Crystal structure of lysozyme
Descriptor: Lysozyme C
Authors:Liang, M.
Deposit date:2021-06-10
Release date:2021-09-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Novel combined crystallization plate for high-throughput crystal screening and in situ data collection at a crystallography beamline.
Acta Crystallogr.,Sect.F, 77, 2021
7D8M
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BU of 7d8m by Molmil
Crystal structure of DyP
Descriptor: Dye-decolorizing peroxidase, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE
Authors:He, C, Jia, R, Wang, T, Li, L.Q.
Deposit date:2020-10-08
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Revealing two important tryptophan residues with completely different roles in a dye-decolorizing peroxidase from Irpex lacteus F17.
Biotechnol Biofuels, 14, 2021
4FVR
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BU of 4fvr by Molmil
Crystal structure of the Jak2 pseudokinase domain mutant V617F (Mg-ATP-bound form)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Tyrosine-protein kinase JAK2
Authors:Bandaranayake, R.M, Hubbard, S.R.
Deposit date:2012-06-29
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F.
Nat.Struct.Mol.Biol., 19, 2012
3W8H
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BU of 3w8h by Molmil
Crystal structure of CCM3 in complex with the C-terminal regulatory domain of STK25
Descriptor: Programmed cell death protein 10, SULFATE ION, Serine/threonine-protein kinase 25
Authors:Xu, X, Wang, D.C, Ding, J.
Deposit date:2013-03-13
Release date:2013-07-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.426 Å)
Cite:Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
Structure, 21, 2013
4FVQ
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BU of 4fvq by Molmil
Crystal structure of the Jak2 pseudokinase domain (Mg-ATP-bound form)
Descriptor: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Bandaranayake, R.M, Hubbard, S.R.
Deposit date:2012-06-29
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F.
Nat.Struct.Mol.Biol., 19, 2012

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數據於2024-06-26公開中

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