1RHM
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3LZU
| Crystal Structure of a Nelfinavir Resistant HIV-1 CRF01_AE Protease variant (N88S) in Complex with the Protease Inhibitor Darunavir. | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, HIV-1 protease | Authors: | Schiffer, C.A, Bandaranayake, R.M. | Deposit date: | 2010-03-01 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways. J.Virol., 84, 2010
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3LZV
| Structure of Nelfinavir-resistant HIV-1 protease (D30N/N88D) in complex with Darunavir. | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, HIV-1 Protease, ... | Authors: | Schiffer, C.A, Kolli, M. | Deposit date: | 2010-03-01 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways. J.Virol., 84, 2010
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1RHJ
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6HQH
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3JTL
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1RHK
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3LZS
| Crystal Structure of HIV-1 CRF01_AE Protease in Complex with Darunavir | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, HIV-1 protease | Authors: | Schiffer, C.A, Bandaranayake, R.M. | Deposit date: | 2010-03-01 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways. J.Virol., 84, 2010
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1RHR
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2GCL
| Structure of the Pob3 Middle domain | Descriptor: | CHLORIDE ION, Hypothetical 63.0 kDa protein in DAK1-ORC1 intergenic region | Authors: | VanDemark, A.P. | Deposit date: | 2006-03-14 | Release date: | 2006-05-23 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition. Mol.Cell, 22, 2006
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1RHQ
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1RHU
| CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A 5,6,7 TRICYCLIC PEPTIDOMIMETIC INHIBITOR | Descriptor: | (3S)-3-[({(2S)-5-[(N-ACETYL-L-ALPHA-ASPARTYL)AMINO]-4-OXO-1,2,4,5,6,7-HEXAHYDROAZEPINO[3,2,1-HI]INDOL-2-YL}CARBONYL)AMINO]-5-(BENZYLSULFANYL)-4-OXOPENTANOIC ACID, Caspase-3 | Authors: | Becker, J.W, Rotonda, J, Soisson, S.M. | Deposit date: | 2003-11-14 | Release date: | 2004-05-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis. J.Med.Chem., 47, 2004
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2GCJ
| Crystal Structure of the Pob3 middle domain | Descriptor: | Hypothetical 63.0 kDa protein in DAK1-ORC1 intergenic region | Authors: | VanDemark, A.P. | Deposit date: | 2006-03-14 | Release date: | 2006-05-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition. Mol.Cell, 22, 2006
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1Z3Y
| Structure of Gun4-1 from Thermosynechococcus elongatus | Descriptor: | putative cytidylyltransferase | Authors: | Davison, P.A, Schubert, H.L, Reid, J.D, Iorg, C.D, Robinson, H, Hill, C.P, Hunter, C.N. | Deposit date: | 2005-03-14 | Release date: | 2005-06-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Biochemical Characterization of Gun4 Suggests a Mechanism for Its Role in Chlorophyll Biosynthesis(,). Biochemistry, 44, 2005
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1Z3X
| Structure of Gun4 from Thermosynechococcus elongatus | Descriptor: | putative cytidylyltransferase | Authors: | Davison, P.A, Schubert, H.L, Reid, J.D, Iorg, C.D, Robinson, H, Hill, C.P, Hunter, C.N. | Deposit date: | 2005-03-14 | Release date: | 2005-06-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and Biochemical Characterization of Gun4 Suggests a Mechanism for Its Role in Chlorophyll Biosynthesis(,). Biochemistry, 44, 2005
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5MZ5
| Crystal structure of aldehyde dehydrogenase 21 (ALDH21) from Physcomitrella patens in its apoform | Descriptor: | 1,2-ETHANEDIOL, ALDH21), DI(HYDROXYETHYL)ETHER, ... | Authors: | Kopecny, D, Koncitikova, R, Briozzo, P, Morera, S. | Deposit date: | 2017-01-30 | Release date: | 2017-08-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The ALDH21 gene found in lower plants and some vascular plants codes for a NADP(+) -dependent succinic semialdehyde dehydrogenase. Plant J., 92, 2017
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4I6M
| Structure of Arp7-Arp9-Snf2(HSA)-RTT102 subcomplex of SWI/SNF chromatin remodeler. | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, PHOSPHATE ION, ... | Authors: | Schubert, H.L, Cairns, B.R, Hill, C.P. | Deposit date: | 2012-11-29 | Release date: | 2013-02-13 | Last modified: | 2017-08-16 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Structure of an actin-related subcomplex of the SWI/SNF chromatin remodeler. Proc.Natl.Acad.Sci.USA, 110, 2013
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4EQ7
| Structure of Atu4243-GABA receptor | Descriptor: | ABC transporter, substrate binding protein (Polyamine), GLYCEROL, ... | Authors: | Morera, S, Planamente, S. | Deposit date: | 2012-04-18 | Release date: | 2012-11-21 | Last modified: | 2012-12-19 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structural basis for selective GABA binding in bacterial pathogens. Mol.Microbiol., 86, 2012
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3S1E
| Pro427Gln mutant of maize cytokinin oxidase/dehydrogenase complexed with N6-isopentenyladenine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokinin dehydrogenase 1, ... | Authors: | Kopecny, D, Briozzo, P, Morera, S. | Deposit date: | 2011-05-15 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Kinetic and structural investigation of the cytokinin oxidase/dehydrogenase active site. Febs J., 283, 2016
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3SZM
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4IQ2
| P21 crystal form of FKBP12.6 | Descriptor: | MALONIC ACID, Peptidyl-prolyl cis-trans isomerase FKBP1B | Authors: | Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G. | Deposit date: | 2013-01-10 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6. Acta Crystallogr.,Sect.D, 70, 2014
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4IQC
| P3121 crystal form of FKBP12.6 | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B | Authors: | Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G. | Deposit date: | 2013-01-11 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6. Acta Crystallogr.,Sect.D, 70, 2014
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3THF
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4L2W
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3V46
| Crystal Structure of Yeast Cdc73 C-Terminal Domain | Descriptor: | Cell division control protein 73 | Authors: | Amrich, C.G, VanDemark, A.P. | Deposit date: | 2011-12-14 | Release date: | 2012-02-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.549 Å) | Cite: | Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin. J.Biol.Chem., 287, 2012
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