5YEI
 
 | | Mechanistic insight into the regulation of Pseudomonas aeruginosa aspartate kinase | | Descriptor: | Aspartokinase, GLYCEROL, LYSINE, ... | | Authors: | Li, C, Yang, M, Liu, L, Peng, C, Li, T, He, L, Song, Y, Zhu, Y, Bao, R. | | Deposit date: | 2017-09-17 | | Release date: | 2018-08-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.301 Å) | | Cite: | Mechanistic insights into the allosteric regulation of Pseudomonas aeruginosa aspartate kinase.
Biochem.J., 475, 2018
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7ZBT
 | | Subtomogram averaging of Rubisco from native Halothiobacillus carboxysomes | | Descriptor: | Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small subunit | | Authors: | Ni, T, Zhu, Y, Yu, X, Sun, Y, Liu, L, Zhang, P. | | Deposit date: | 2022-03-24 | | Release date: | 2022-07-20 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure and assembly of cargo Rubisco in two native alpha-carboxysomes.
Nat Commun, 13, 2022
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5Z9X
 | | Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 in complex with an RNA substrate | | Descriptor: | MAGNESIUM ION, RNA (5'-R(P*GP*CP*CP*CP*AP*UP*UP*AP*G)-3'), SULFATE ION, ... | | Authors: | Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Gan, J, Cao, C, Huang, Y, Chen, X, Ma, J. | | Deposit date: | 2018-02-05 | | Release date: | 2018-06-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
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5Z9Z
 | | The C-terminal RRM domain of Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 (E329A/E330A/E332A) | | Descriptor: | CITRATE ANION, Small RNA degrading nuclease 1 | | Authors: | Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Cao, C, Gan, J, Huang, Y, Chen, X, Ma, J. | | Deposit date: | 2018-02-05 | | Release date: | 2018-06-27 | | Last modified: | 2018-10-03 | | Method: | X-RAY DIFFRACTION (2.049 Å) | | Cite: | Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
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6ANF
 | | Design of a short thermo-stable alpha-helix embedded in a macrocycle | | Descriptor: | 3,3'-dimethyl-1,1'-biphenyl, Capped-strapped peptide | | Authors: | Wu, H, Acharyya, A, Wu, Y, Liu, L, Jo, H, Gai, F, DeGrado, W.F. | | Deposit date: | 2017-08-13 | | Release date: | 2018-02-21 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Design of a Short Thermally Stable alpha-Helix Embedded in a Macrocycle.
Chembiochem, 19, 2018
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4GHT
 | | Crystal structure of EV71 3C proteinase in complex with AG7088 | | Descriptor: | 3C proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | Authors: | Chen, C, Wu, C, Cai, Q, Li, N, Peng, X, Cai, Y, Yin, K, Chen, X, Wang, X, Zhang, R, Liu, L, Chen, S, Li, J, Lin, T. | | Deposit date: | 2012-08-08 | | Release date: | 2013-06-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
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4GM8
 | | Crystal structure of human WD repeat domain 5 with compound MM-102 | | Descriptor: | MM-102, WD repeat-containing protein 5 | | Authors: | Karatas, H, Townsend, E.C, Chen, Y, Bernard, D, Cao, F, Liu, L, Lei, M, Dou, Y, Wang, S. | | Deposit date: | 2012-08-15 | | Release date: | 2013-07-31 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction.
J.Am.Chem.Soc., 135, 2013
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4GM9
 | | Crystal structure of human WD repeat domain 5 with compound MM-401 | | Descriptor: | MM-401, WD repeat-containing protein 5 | | Authors: | Karatas, H, Townsend, E.C, Chen, Y, Bernard, D, Liu, L, Dou, Y, Lei, M, Wang, S. | | Deposit date: | 2012-08-15 | | Release date: | 2014-02-19 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of human WD repeat domain 5 with compound MM-401
To be Published
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8HR1
 | | Cryo-EM structure of SSX1 bound to the unmodified nucleosome at a resolution of 3.02 angstrom | | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | Authors: | Zebin, T, Ai, H.S, Ziyu, X, Man, P, Liu, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-09-13 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024
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8HQY
 | | Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom | | Descriptor: | DNA (136-MER), DNA (137-MER), Histone H2A type 1-B/E, ... | | Authors: | Zebin, T, Ai, H.S, Ziyu, X, GuoChao, C, Man, P, Liu, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-09-27 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024
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8IEJ
 | | RNF20-RNF40/hRad6A-Ub/nucleosome complex | | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ... | | Authors: | Ai, H, Deng, Z, Sun, M, Du, Y, Pan, M, Liu, L. | | Deposit date: | 2023-02-15 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.
Mol.Cell, 83, 2023
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8IEG
 | | Bre1(mRBD-RING)/Rad6-Ub/nucleosome complex | | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase BRE1, Histone H2A type 1-B/E, ... | | Authors: | Ai, H, Deng, Z, Pan, M, Liu, L. | | Deposit date: | 2023-02-15 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (3.44 Å) | | Cite: | Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.
Mol.Cell, 83, 2023
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6BTA
 | | CypA Mutant - S99T C115S | | Descriptor: | Peptidyl-prolyl cis-trans isomerase A | | Authors: | Fraser, J.S, Kenner, L.R, Liu, L. | | Deposit date: | 2017-12-06 | | Release date: | 2018-04-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Rescue of conformational dynamics in enzyme catalysis by directed evolution.
Nat Commun, 9, 2018
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4GM3
 | | Crystal structure of human WD repeat domain 5 with compound MM-101 | | Descriptor: | MM-101, WD repeat-containing protein 5 | | Authors: | Karatas, H, Townsend, E.C, Chen, Y, Bernard, D, Cao, F, Liu, L, Lei, M, Dou, Y, Wang, S. | | Deposit date: | 2012-08-15 | | Release date: | 2013-07-31 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.393 Å) | | Cite: | High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction.
J.Am.Chem.Soc., 135, 2013
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4IC6
 | | Crystal structure of Deg8 | | Descriptor: | Protease Do-like 8, chloroplastic | | Authors: | Gong, W, Sun, W, Fan, H, Gao, F, Liu, L. | | Deposit date: | 2012-12-10 | | Release date: | 2013-05-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structures of Arabidopsis Deg5 and Deg8 reveal new insights into HtrA proteases
Acta Crystallogr.,Sect.D, 69, 2013
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6B17
 | | Design of a short thermally stable alpha-helix embedded in a macrocycle | | Descriptor: | 3,3'-dimethyl-1,1'-biphenyl, Capped-strapped peptide | | Authors: | Wu, H, Acharyya, A, Wu, Y, Liu, L, Jo, H, Gai, F, DeGrado, W.F. | | Deposit date: | 2017-09-17 | | Release date: | 2018-02-21 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Design of a Short Thermally Stable alpha-Helix Embedded in a Macrocycle.
Chembiochem, 19, 2018
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4GHQ
 | | Crystal structure of EV71 3C proteinase | | Descriptor: | 3C proteinase | | Authors: | Chen, C, Wu, C, Cai, Q, Li, N, Peng, X, Cai, Y, Yin, K, Chen, X, Wang, X, Zhang, R, Liu, L, Chen, S, Li, J, Lin, T. | | Deposit date: | 2012-08-08 | | Release date: | 2013-06-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
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4IC5
 | | Crystal structure of Deg5 | | Descriptor: | CALCIUM ION, Protease Do-like 5, chloroplastic | | Authors: | Gong, W, Sun, W, Fan, H, Gao, F, Liu, L. | | Deposit date: | 2012-12-10 | | Release date: | 2013-05-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.607 Å) | | Cite: | The structures of Arabidopsis Deg5 and Deg8 reveal new insights into HtrA proteases
Acta Crystallogr.,Sect.D, 69, 2013
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4J4G
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4J4F
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4J4E
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4J4C
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4J4D
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4QDJ
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4QDK
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