8GTN
| |
8GTK
| |
8GTJ
| |
6N7I
| Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (gp4(5)-DNA) | Descriptor: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | Authors: | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | Deposit date: | 2018-11-27 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6N7T
| Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form III) | Descriptor: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | Authors: | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | Deposit date: | 2018-11-28 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6N7S
| Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form II) | Descriptor: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | Authors: | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | Deposit date: | 2018-11-28 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6N7N
| Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I) | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ... | Authors: | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | Deposit date: | 2018-11-27 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6N9W
| Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2) | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | Authors: | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | Deposit date: | 2018-12-04 | Release date: | 2019-03-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6J56
| Crystal structure of Myosin VI CBD in complex with Tom1 MBM | Descriptor: | Peptide from Target of Myb protein 1, Unconventional myosin-VI | Authors: | Hu, S, Pan, L. | Deposit date: | 2019-01-10 | Release date: | 2019-08-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering. Nat Commun, 10, 2019
|
|
7EAA
| crystal structure of NDP52 SKICH domain in complex with RB1CC1 coiled-coil domain | Descriptor: | Calcium-binding and coiled-coil domain-containing protein 2, RB1-inducible coiled-coil protein 1 | Authors: | Fu, T, Pan, L. | Deposit date: | 2021-03-06 | Release date: | 2021-12-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52. Sci Adv, 7, 2021
|
|
7EA7
| crystal structure of NAP1 LIR in complex with GABARAP | Descriptor: | Gamma-aminobutyric acid receptor-associated protein, NAP1_LIR motif | Authors: | Fu, T, Pan, L. | Deposit date: | 2021-03-06 | Release date: | 2021-12-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52. Sci Adv, 7, 2021
|
|
7EA2
| crystal structure of NAP1 FIR in complex with RB1CC1 Claw domain | Descriptor: | 5-azacytidine-induced protein 2,RB1-inducible coiled-coil protein 1, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Fu, T, Pan, L. | Deposit date: | 2021-03-06 | Release date: | 2021-12-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52. Sci Adv, 7, 2021
|
|
5GIY
| HSA-Palmitic acid-[RuCl5(ind)]2- | Descriptor: | PALMITIC ACID, Serum albumin, pentakis(chloranyl)-(1~{H}-indazol-2-ium-2-yl)ruthenium(1-) | Authors: | Yang, F, Wang, T. | Deposit date: | 2016-06-25 | Release date: | 2017-07-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.543 Å) | Cite: | Structure of HSA-Palmitic acid-[RuCl5(ind)]2- To Be Published
|
|
7YFK
| The structure of human pregnane X receptor in complex with an SRC-1 coactivator peptide and a limonoid compound, nomilin | Descriptor: | Nomilin, Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1 | Authors: | Xia, Y, Yao, D, Huang, C, Cao, Y. | Deposit date: | 2022-07-08 | Release date: | 2023-06-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions. Nat Commun, 14, 2023
|
|
6JPE
| Crystal structure of FGFR4 kinase domain with irreversible inhibitor 1 | Descriptor: | Fibroblast growth factor receptor 4, N-[2-[[6-[2-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]amino]pyridin-3-yl]pyrimidin-4-yl]amino]-3-methyl-phenyl]prop-2-enamide, SULFATE ION | Authors: | Chen, X, Dai, S, Zhou, Z, Chen, Y. | Deposit date: | 2019-03-26 | Release date: | 2020-05-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma. J.Med.Chem., 63, 2020
|
|