8XAX
 
 | |
8XAW
 | |
5XJR
 | |
8CXB
 | | Human PA28-20S (PA28-4a3b) | | Descriptor: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | | Authors: | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | | Deposit date: | 2022-05-20 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
5WQ4
 | | Crystal structure of OPTN and linear diubiquitin complex | | Descriptor: | Optineurin, ubiquitin | | Authors: | Li, F, Pan, L. | | Deposit date: | 2016-11-23 | | Release date: | 2017-12-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.
Autophagy, 14, 2018
|
|
6TXZ
 | | FAB PART OF M6903 IN COMPLEX WITH HUMAN TIM3 | | Descriptor: | Fab H, Fab L, Hepatitis A virus cellular receptor 2 | | Authors: | Musil, D, Sood, V. | | Deposit date: | 2020-01-15 | | Release date: | 2020-04-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.06 Å) | | Cite: | Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody.
Oncoimmunology, 9, 2020
|
|
5WP3
 | | Crystal Structure of EED in complex with EB22 | | Descriptor: | EB22, Polycomb protein EED, UNKNOWN ATOM OR ION | | Authors: | Dong, C, Tempel, W, Zhu, L, Moody, J.D, Baker, D, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2017-08-03 | | Release date: | 2017-09-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
7CYV
 | | Crystal structure of FD20, a neutralizing single-chain variable fragment (scFv) in complex with SARS-CoV-2 Spike receptor-binding domain (RBD) | | Descriptor: | Spike protein S1, The heavy chain variable region of the scFv FD20,The light chain variable region of the scFv FD20, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Li, Y, Li, T, Lai, Y, Cai, H, Yao, H, Li, D. | | Deposit date: | 2020-09-04 | | Release date: | 2021-09-15 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3.13 Å) | | Cite: | Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody.
Embo Mol Med, 13, 2021
|
|
7CPV
 | | Cryo-EM structure of 80S ribosome from mouse testis | | Descriptor: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | | Authors: | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | | Deposit date: | 2020-08-08 | | Release date: | 2022-02-02 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | A male germ-cell-specific ribosome controls male fertility.
Nature, 612, 2022
|
|
7CPU
 | | Cryo-EM structure of 80S ribosome from mouse kidney | | Descriptor: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | | Authors: | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | | Deposit date: | 2020-08-08 | | Release date: | 2022-02-02 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.82 Å) | | Cite: | A male germ-cell-specific ribosome controls male fertility.
Nature, 612, 2022
|
|
5X0W
 | | Molecular mechanism for the binding between Sharpin and HOIP | | Descriptor: | E3 ubiquitin-protein ligase RNF31, Sharpin | | Authors: | Liu, J, Li, F, Cheng, X, Pan, L. | | Deposit date: | 2017-01-23 | | Release date: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly
Cell Rep, 21, 2017
|
|
5XJQ
 | |
7C00
 | | Crystal structure of the SRCR domain of human SCARA5. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Scavenger receptor class A member 5 | | Authors: | Yu, B, He, Y. | | Deposit date: | 2020-04-29 | | Release date: | 2020-09-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Interactions of ferritin with scavenger receptor class A members.
J.Biol.Chem., 295, 2020
|
|
7BZZ
 | | Crystal structure of the SRCR domain of mouse SCARA5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Scavenger receptor class A member 5 | | Authors: | Yu, B, He, Y. | | Deposit date: | 2020-04-29 | | Release date: | 2020-09-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Interactions of ferritin with scavenger receptor class A members.
J.Biol.Chem., 295, 2020
|
|
9C80
 | | Co-structure of SARS-CoV-2 (COVID-19 with covalent inhibitor | | Descriptor: | (5R,7S,8R)-7-(2-fluorophenyl)-3-[(2-fluorophenyl)carbamoyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-5-carboxylic acid, 3C-like proteinase nsp5 | | Authors: | Ornelas, E, Knapp, M.S. | | Deposit date: | 2024-06-11 | | Release date: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Identification of Potent, Broad-Spectrum Coronavirus Main Protease Inhibitors for Pandemic Preparedness.
J.Med.Chem., 2024
|
|
9C8Q
 | |
8IEM
 | | Cryo-EM structure of ATP13A2 in the E2P state | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Polyamine-transporting ATPase 13A2, ... | | Authors: | Liu, Z.M, Mu, J.Q, Xue, C.Y. | | Deposit date: | 2023-02-15 | | Release date: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
|
|
8IEN
 | | Cryo-EM structure of ATP13A2 in the E2-Pi state | | Descriptor: | MAGNESIUM ION, Polyamine-transporting ATPase 13A2, SPERMINE, ... | | Authors: | Liu, Z.M, Mu, J.Q, Xue, C.Y. | | Deposit date: | 2023-02-15 | | Release date: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
|
|
8IES
 | | Cryo-EM structure of ATP13A2 in the E1P-ADP state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Polyamine-transporting ATPase 13A2, ... | | Authors: | Liu, Z.M, Mu, J.Q, Xue, C.Y. | | Deposit date: | 2023-02-15 | | Release date: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
|
|
8IER
 | |
8IEL
 | |
8IEK
 | |
8IEO
 | | Cryo-EM structure of ATP13A2 in the nominal E1P state | | Descriptor: | MAGNESIUM ION, Polyamine-transporting ATPase 13A2, SPERMINE, ... | | Authors: | Liu, Z.M, Mu, J.Q, Xue, C.Y. | | Deposit date: | 2023-02-15 | | Release date: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
|
|
8IND
 | | Crystal structure of UGT74AN3-UDP-RES | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-[(1R,2S,4R,6R,7R,10S,11S,14S,16R)-14-hydroxy-7,11-dimethyl-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-6-yl]pyran-2-one, Glycosyltransferase, ... | | Authors: | Huang, W. | | Deposit date: | 2023-03-09 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3
Acs Catalysis, 14, 2024
|
|
8INV
 | | Crystal structure of UGT74AN3-UDP-BUF | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, ... | | Authors: | Long, F, Huang, W. | | Deposit date: | 2023-03-10 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3
Acs Catalysis, 14, 2024
|
|
