8YL9
 
 | | Crystal structures of terpene synthases complexed with a substrate mimic | | Descriptor: | MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, PYROPHOSPHATE, ... | | Authors: | Xu, M, Ma, M. | | Deposit date: | 2024-03-05 | | Release date: | 2024-04-24 | | Last modified: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural Insights Into the Terpene Cyclization Domains of Two Fungal Sesterterpene Synthases and Enzymatic Engineering for Sesterterpene Diversification.
Angew.Chem.Int.Ed.Engl., 63, 2024
|
|
8YLA
 | | Crystal structures of terpene synthases complexed with a substrate mimic | | Descriptor: | MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, PYROPHOSPHATE, ... | | Authors: | Xu, M, Ma, M. | | Deposit date: | 2024-03-05 | | Release date: | 2024-04-24 | | Last modified: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structural Insights Into the Terpene Cyclization Domains of Two Fungal Sesterterpene Synthases and Enzymatic Engineering for Sesterterpene Diversification.
Angew.Chem.Int.Ed.Engl., 63, 2024
|
|
5F8X
 | | The crystal structure of human plasma kallikrein in complex with its peptide inhibitor pkalin-3 | | Descriptor: | CYS-PRO-ALA-ARG-PHE-M70-ALA-LEU-TRP-CYS, Plasma kallikrein, SULFATE ION, ... | | Authors: | Xu, M, Jiang, L, Xu, P, Luo, Z, Andreasen, P, Huang, M. | | Deposit date: | 2015-12-09 | | Release date: | 2016-12-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | The Crystal Structure Of Human Plasma Kallikrein In Complex With Its Peptide Inhibitor Pkalin-3
To Be Published
|
|
5F8T
 | | The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2 | | Descriptor: | CYS-PRO-LYS-ARG-PHE-M70-ALA-LEU-PHE-CYS, Plasma kallikrein light chain, SULFATE ION, ... | | Authors: | Xu, M, Jiang, L, Xu, P, Luo, Z, Andreasen, P, Huang, M. | | Deposit date: | 2015-12-09 | | Release date: | 2016-12-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2
To Be Published
|
|
5F8Z
 | | The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-1 | | Descriptor: | CYS-PRO-ALA-ARG-PHE-M70-ALA-LEU-PHE-CYS, Plasma kallikrein LIGHT CHAIN, SULFATE ION, ... | | Authors: | Xu, M, Jiang, L, Xu, P, Luo, Z, Andreasen, P, Huang, M. | | Deposit date: | 2015-12-09 | | Release date: | 2016-12-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-1
To Be Published
|
|
8FPQ
 | | PCSK9 in complex with an inhibitor | | Descriptor: | CALCIUM ION, MCR-PHE-VAL-PRO-THR-THR-BIF-MAA-BIF-MAA-GLU-ALA-PRO-ALA-NEH inhibitor, Proprotein convertase subtilisin/kexin type 9 | | Authors: | Xu, M, Chopra, R. | | Deposit date: | 2023-01-05 | | Release date: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.503 Å) | | Cite: | pcsk9 in complex with cyclic peptide
To Be Published
|
|
8FVO
 | | PCSK9 in complex with an inhibitor | | Descriptor: | CALCIUM ION, MCR-ALA-7T2-GLY-004-7T2-SER-7T2-ALA-GLY-NH2 inhibitor, Proprotein convertase subtilisin/kexin type 9 | | Authors: | Xu, M, Chopra, R. | | Deposit date: | 2023-01-19 | | Release date: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.652 Å) | | Cite: | pcsk9 in complex with cyclic peptide
To Be Published
|
|
8FVP
 | | PCSK9 in complex with an inhibitor | | Descriptor: | CALCIUM ION, PPI-YD5-NLE-7T2-SER-7T2-DPP-GLY-NH2 inhibitor, Proprotein convertase subtilisin/kexin type 9 | | Authors: | Xu, M, Chopra, R. | | Deposit date: | 2023-01-19 | | Release date: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.602 Å) | | Cite: | pcsk9 in complex with cyclic peptide
To Be Published
|
|
8FVM
 | | PCSK9 in complex with an inhibitor | | Descriptor: | CALCIUM ION, DGN-DVA-YC3-GLU-PRO-THR-THR-PHE-MAA-A1BC0 inhibitor, Proprotein convertase subtilisin/kexin type 9 | | Authors: | Xu, M, Chopra, R. | | Deposit date: | 2023-01-19 | | Release date: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.852 Å) | | Cite: | pcsk9 in complex with cyclic peptide
To Be Published
|
|
8FVN
 | | PCSK9 in complex with an inhibitor | | Descriptor: | MCR-ALO-MAA-ALA-MAA-NLE-7T2-SER-7T2-ALA-NH2 inhibitor, Proprotein convertase subtilisin/kexin type 9 | | Authors: | Xu, M, Chopra, R. | | Deposit date: | 2023-01-19 | | Release date: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | pcsk9 in complex with cyclic peptide
To Be Published
|
|
8FVQ
 | | PCSK9 in complex with an inhibitor | | Descriptor: | ACE-PHE-VAL-DAB-THR-THR-PHE-MAA-BIF-YBR inhibitor, Proprotein convertase subtilisin/kexin type 9 | | Authors: | Xu, M, Chopra, R. | | Deposit date: | 2023-01-19 | | Release date: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | pcsk9 in complex with cyclic peptide
To Be Published
|
|
8FVL
 | | PCSK9 in complex with an inhibitor | | Descriptor: | Proprotein convertase subtilisin/kexin type 9, YBX-YC3-VAL-PRO-THR-THR-PHE-MAA-CYS-MN1 inhibitor | | Authors: | Xu, M, Chopra, R. | | Deposit date: | 2023-01-19 | | Release date: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.961 Å) | | Cite: | pcsk9 in complex with cyclic peptide
To Be Published
|
|
8FPO
 | | PCSK9 in complex with an inhibitor | | Descriptor: | CALCIUM ION, MCR-ALA-7T2-GLY-004-7T2-SER-7T2-0NC inhibitor, Proprotein convertase subtilisin/kexin type 9 | | Authors: | Xu, M, Chopra, R. | | Deposit date: | 2023-01-05 | | Release date: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.997 Å) | | Cite: | pcsk9 in complex with cyclic peptide
To Be Published
|
|
5GVT
 | |
8TA5
 | | Title: Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with asymmetric C-terminal | | Descriptor: | Chloride channel protein 2 | | Authors: | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | | Deposit date: | 2023-06-26 | | Release date: | 2024-01-31 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
|
|
8TA4
 | | Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with symmetric C-terminal | | Descriptor: | CHLORIDE ION, Chloride channel protein 2 | | Authors: | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | | Deposit date: | 2023-06-26 | | Release date: | 2024-01-31 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
|
|
8TA2
 | | Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with bound inhibitor AK-42 | | Descriptor: | 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, CHLORIDE ION, Chloride channel protein 2 | | Authors: | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | | Deposit date: | 2023-06-26 | | Release date: | 2024-01-31 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.74 Å) | | Cite: | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
|
|
8TA3
 | | Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain Apo state with resolved N-terminal hairpin | | Descriptor: | CHLORIDE ION, Chloride channel protein 2 | | Authors: | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | | Deposit date: | 2023-06-26 | | Release date: | 2024-01-31 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.46 Å) | | Cite: | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
|
|
8TA6
 | | Cryo-EM structure of the human CLC-2 chloride channel C-terminal domain | | Descriptor: | Chloride channel protein 2 | | Authors: | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | | Deposit date: | 2023-06-26 | | Release date: | 2024-01-31 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (4.03 Å) | | Cite: | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
|
|
7V4Y
 | | TTHA1264/TTHA1265 complex | | Descriptor: | Putative zinc protease, ZINC ION, Zinc-dependent peptidase | | Authors: | Xu, M, Xu, Q, Ran, T, Wang, W, Sun, B, Wang, Q. | | Deposit date: | 2021-08-16 | | Release date: | 2022-06-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of TTHA1265 and TTHA1264/TTHA1265 complex reveal an intrinsic heterodimeric assembly.
Int.J.Biol.Macromol., 207, 2022
|
|
6A8O
 | | Crystal structures of the serine protease domain of murine plasma kallikrein with peptide inhibitor mupain-1-16 | | Descriptor: | Plasma kallikrein, alpha-D-mannopyranose, peptide inhibitor,, ... | | Authors: | Xu, M, Jiang, L, Huang, M. | | Deposit date: | 2018-07-09 | | Release date: | 2019-07-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Crystal structure of plasma kallikrein reveals the unusual flexibility of the S1 pocket triggered by Glu217.
Febs Lett., 592, 2018
|
|
8H0M
 | | Crystal structure of VioD | | Descriptor: | (2S)-2-ethylhexan-1-ol, FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, ... | | Authors: | Xu, M, Ran, T, Wang, W. | | Deposit date: | 2022-09-29 | | Release date: | 2023-04-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.702 Å) | | Cite: | Structural basis for substrate binding and catalytic mechanism of the key enzyme VioD in the violacein synthesis pathway.
Proteins, 91, 2023
|
|
5GZS
 | | Structure of VC protein | | Descriptor: | ARGININE, GGDEF family protein | | Authors: | Xu, M, Wang, Y.Z, Yang, X.A, Xie, W, Jiang, T. | | Deposit date: | 2016-10-01 | | Release date: | 2017-08-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | Structural studies of the periplasmic portion of the diguanylate cyclase CdgH from Vibrio cholerae.
Sci Rep, 7, 2017
|
|
3GGR
 | | Crystal Structure of the Human Rad9-Hus1-Rad1 complex | | Descriptor: | Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1 | | Authors: | Xu, M, Bai, L, Hang, H.Y, Jiang, T. | | Deposit date: | 2009-03-02 | | Release date: | 2009-06-16 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex
J.Biol.Chem., 284, 2009
|
|
5EB3
 | | VB6-bound protein | | Descriptor: | 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol, SULFATE ION, YfiR | | Authors: | Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T. | | Deposit date: | 2015-10-17 | | Release date: | 2016-05-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system
Protein Cell, 7, 2016
|
|
