5CCA
| Crystal structure of Mtb toxin | Descriptor: | Endoribonuclease MazF3 | Authors: | Cascio, D, Arbing, M, de Serrano, V, Eisenberg, D, Miallau, L, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2015-07-01 | Release date: | 2016-09-07 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of Mtb toxin To Be Published
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4Q0G
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1HX5
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1QPO
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1Q7T
| Rv1170 (MshB) from Mycobacterium tuberculosis | Descriptor: | SULFATE ION, hypothetical protein Rv1170, octyl beta-D-glucopyranoside | Authors: | McCarthy, A.A, Peterson, N.A, Knijff, R, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-08-20 | Release date: | 2004-01-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of MshB from Mycobacterium tuberculosis, a Deacetylase Involved in Mycothiol Biosynthesis. J.Mol.Biol., 335, 2004
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6UNC
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2A7Y
| Solution Structure of the Conserved Hypothetical Protein Rv2302 from the Bacterium Mycobacterium tuberculosis | Descriptor: | Hypothetical protein Rv2302/MT2359 | Authors: | Buchko, G.W, Kim, C.-Y, Terwilliger, T.C, Kennedy, M.A, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2005-07-06 | Release date: | 2005-08-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the conserved hypothetical protein Rv2302 from Mycobacterium tuberculosis. J.Bacteriol., 188, 2006
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2A15
| X-ray Crystal Structure of RV0760 from Mycobacterium Tuberculosis at 1.68 Angstrom Resolution | Descriptor: | HYPOTHETICAL PROTEIN Rv0760c, NICOTINAMIDE | Authors: | Garen, C.R, Cherney, M.M, James, M.N.G, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2005-06-17 | Release date: | 2005-10-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase Biochim.Biophys.Acta, 1784, 2008
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2QKX
| N-acetyl glucosamine 1-phosphate uridyltransferase from Mycobacterium tuberculosis complex with N-acetyl glucosamine 1-phosphate | Descriptor: | 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, Bifunctional protein glmU | Authors: | Zhang, Z, Squire, C.J, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2007-07-11 | Release date: | 2008-07-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure and function of GlmU from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 65, 2009
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2AQ6
| X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 1.7 a resolution | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, PYRIDOXINE 5'-PHOSPHATE OXIDASE | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Garen, C, James, M.N, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2005-08-17 | Release date: | 2005-08-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate. Acta Crystallogr.,Sect.D, 61, 2005
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6TZV
| Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis | Descriptor: | 4'-[(6-chloro-1,3-benzothiazol-2-yl)oxy]-6-hydroxy-4,4-dimethyl-4,5-dihydro[1,1'-biphenyl]-2(3H)-one, Probable propionyl-CoA carboxylase beta chain 6 | Authors: | Reddy, M.C.M, Zhou, N, Sacchettini, J, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2019-08-13 | Release date: | 2020-08-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.388 Å) | Cite: | Novel herbicidal derivatives that inhibit carboxyltransferase subunit of the acetyl-CoA carboxylase in Mycobacterium tuberculosis To Be Published
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2A87
| Crystal Structure of M. tuberculosis Thioredoxin reductase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Akif, M, Suhre, K, Verma, C, Mande, S.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2005-07-07 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Conformational flexibility of Mycobacterium tuberculosis thioredoxin reductase: crystal structure and normal-mode analysis. Acta Crystallogr.,Sect.D, 61, 2005
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7SFR
| Unmethylated Mtb Ribosome 50S with SEQ-9 | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Xing, Z, Cui, Z, Zhang, J, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2021-10-04 | Release date: | 2022-10-12 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents. Cell, 186, 2023
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3BZQ
| High resolution crystal structure of Nitrogen Regulatory Protein (Rv2919c) of Mycobacterium tuberculosis | Descriptor: | Nitrogen regulatory protein P-II | Authors: | Reddy, M.C, Palaninathan, S.K, Shetty, N.D, Owen, J.L, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2008-01-18 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein. Protein Sci., 19, 2010
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8GKF
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3C90
| The 1.25 A Resolution Structure of Phosphoribosyl-ATP Pyrophosphohydrolase from Mycobacterium tuberculosis, crystal form II | Descriptor: | Phosphoribosyl-ATP pyrophosphatase | Authors: | Javid-Majd, F, Yang, D, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2008-02-14 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 64, 2008
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7SVT
| Mycobacterium tuberculosis 3-hydroxyl-ACP dehydratase HadAB in complex with 1,3-diarylpyrazolyl-acylsulfonamide inhibitor | Descriptor: | (3R)-hydroxyacyl-ACP dehydratase subunit HadB, 1,2-ETHANEDIOL, 3-[1-(4-bromophenyl)-3-(4-chlorophenyl)-1H-pyrazol-4-yl]-N-(methanesulfonyl)propanamide, ... | Authors: | Krieger, I.V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2021-11-19 | Release date: | 2022-11-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | 1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis . Acs Infect Dis., 8, 2022
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6AU9
| Crystal structure of Mycobacterium tuberculosis malate synthase in complex with dioxine-phenyldiketoacid | Descriptor: | (2Z)-4-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-4-oxobut-2-enoic acid, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Krieger, I.V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2017-08-31 | Release date: | 2018-09-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Anion-pi Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids. J Chem Inf Model, 58, 2018
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6APZ
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6ASU
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6AS6
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7N8L
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7N8E
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7N8M
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5KVU
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